Giorgio Berton

Overview

Best Publications

• Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin

  Elena Zenaro;Enrica Caterina Pietronigro;Vittorina Della Bianca;Gennj Piacentino

  848
  Citations

• Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions.

  Clifford Lowell;L Fumagalli;G Berton

  425
  Citations

• Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases.

  Attila Mócsai;Zoltán Jakus;Tibor Vántus;Giorgio Berton

  352
  Citations

• Integrin signalling in neutrophils and macrophages.

  Giorgio Berton;Clifford A Lowell

  320
  Citations

• CXCL1/Macrophage Inflammatory Protein-2-Induced Angiogenesis In Vivo Is Mediated by Neutrophil-Derived Vascular Endothelial Growth Factor-A

  Patrizia Scapini;Monica Morini;Cristina Tecchio;Simona Minghelli

  319
  Citations

• Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule.

  Carlo Laudanna;Gabriela Constantin;P Baron;E Scarpini

  274
  Citations

• Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck

  Attila Mócsai;Attila Mócsai;Erzsébet Ligeti;Clifford A. Lowell;Giorgio Berton

  266
  Citations

• Src and Syk kinases: key regulators of phagocytic cell activation

  Giorgio Berton;Attila Mócsai;Clifford A. Lowell

  254
  Citations

• Generation of signals activating neutrophil functions by leukocyte integrins: LFA-1 and gp150/95, but not CR3, are able to stimulate the respiratory burst of human neutrophils.

  G. Berton;Carlo Laudanna;Claudio Sorio;F. Rossi

  250
  Citations

• Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

  Clifford A. Lowell;Giorgio Berton

  235
  Citations

• IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucyl-phenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway.

  M A Cassatella;F Bazzoni;M Ceska;I Ferro

  224
  Citations

• Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils.

  Giorgio Berton;Laura Fumagalli;Carlo Laudanna;Claudio Sorio

  216
  Citations

• Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages.

  Patrick W. Suen;Dusko Ilic;Elena Caveggion;Giorgio Berton

  211
  Citations

• Signaling by adhesion in human neutrophils: activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophils spreading over fibrinogen.

  S. R. Yan;M. Huang;Giorgio Berton

  189
  Citations

• Integrin signal transduction in myeloid leukocytes.

  Clifford A. Lowell;Giorgio Berton

  188
  Citations

• Gamma interferon is able to enhance the oxidative metabolism of human neutrophils.

  Giorgio Berton;Lucia Zeni;Marco A. Cassatella;Filippo Rossi

  181
  Citations

• Soluble interleukin-2 receptors in the sera of patients with hairy cell leukemia: relationship with the effect of recombinant alpha-interferon therapy on clinical parameters and natural killer in vitro activity.

  M Chilosi;G Semenzato;G Cetto;A Ambrosetti

  160
  Citations

• The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating β2 integrin affinity and valency in neutrophils, but are required for β2 integrin-mediated outside-in signaling involved in sustained adhesion

  Cinzia Giagulli;Linda Ottoboni;Elena Caveggion;Barbara Rossi

  160
  Citations

• Deficiency of Src family kinases Fgr and Hck results in activation of erythrocyte K/Cl cotransport.

  L De Franceschi;L Fumagalli;O Olivieri;R Corrocher

  159
  Citations

• Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

  Ilaria Iacobucci;Annalisa Lonetti;Francesca Messa;Daniela Cilloni

  150
  Citations