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Gabriela Constantin

Gabriela Constantin

D-Index & Metrics

Immunology

D-Index
45
Citations
13241
World Ranking
4668
National Ranking
204

Overview

Gabriela Constantin is affiliated with the University of Verona in Italy. Their research spans several interconnected areas within biochemistry, genetics, molecular biology, medicine, and neuroscience. Their scholarly work notably emphasizes the investigation of neuroinflammation and neurodegeneration mechanisms, with a particular focus on Alzheimer's disease and multiple sclerosis.

The scientist's publication record includes studies on a variety of topics related to immune and neurological functions. Their main research themes cover:

  • Neuroinflammation and neurodegeneration mechanisms
  • Alzheimer's disease research and treatments
  • Multiple sclerosis research studies
  • Barrier structure and function studies
  • Cell adhesion molecules research
  • Immune cells in cancer
  • T-cell and B-cell immunology

Gabriela Constantin's research contributions frequently appear in the following venues:

  • Frontiers in Immunology
  • Frontiers in Cell and Developmental Biology
  • Nature Reviews Immunology
  • Frontiers in Aging Neuroscience
  • Frontiers in Cellular Neuroscience

Selected recent papers illustrate the breadth of their focus in neuroimmune interactions and central nervous system disorders:

  • In vitro Models of Neurodegenerative Diseases, 2020, Frontiers in Cell and Developmental Biology
  • Neuroinflammation in Alzheimer Disease, 2024, Nature Reviews Immunology
  • Common Peripheral Immunity Mechanisms in Multiple Sclerosis and Alzheimer's Disease, 2021, Frontiers in Immunology
  • The Role of Neutrophils in the Dysfunction of Central Nervous System Barriers, 2022, Frontiers in Aging Neuroscience
  • The Interplay Between T Helper Cells and Brain Barriers in the Pathogenesis of Multiple Sclerosis, 2023, Frontiers in Cellular Neuroscience

The scientist's work integrates aspects of immunology and neurology with molecular biology methods to better understand the pathophysiology of neurodegenerative and neuroinflammatory disorders.

Collaborations form a significant part of their research activities. Frequent co-authors include:

  • Gabriele Angelini
  • Elena Zenaro
  • Barbara Rossi
  • Eleonora Terrabuio
  • Enrica Pietronigro

Within subfields, their research emphasis extends over:

  • Molecular biology
  • Immunology
  • Neurology
  • Physiology
  • Pathology and forensic medicine

This multidisciplinary approach situates Gabriela Constantin's work at the interface of immune system dynamics and neurological disease mechanisms, contributing to the understanding of cellular and molecular processes underlying disorders such as Alzheimer's disease and multiple sclerosis.

Best Publications

  • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism.

    Stefano Pluchino;Lucia Zanotti;Barbara Rossi;Elena Brambilla

  • Functional morphology of the blood-brain barrier in health and disease.

    Stefan Liebner;Rick M. Dijkhuizen;Yvonne Reiss;Karl H. Plate

  • Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin

    Elena Zenaro;Enrica Caterina Pietronigro;Vittorina Della Bianca;Gennj Piacentino

  • The blood-brain barrier in Alzheimer's disease.

    Elena Zenaro;Gennj Piacentino;Gabriela Constantin

  • Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide.

    Marco Antonio Cassatella;L. Meda;S. Bonora;M. Ceska

  • Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow.

    Gabriela Constantin;Meytham Majeed;Cinzia Giagulli;Laura Piccio

  • A role for leukocyte-endothelial adhesion mechanisms in epilepsy

    Paolo F Fabene;Graciela Navarro Mora;Marianna Martinello;Barbara Rossi

  • Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis†‡§

    Gabriela Constantin;Silvia Marconi;Barbara Rossi;Stefano Angiari

  • Regulation of leukocyte recruitment by the long pentraxin PTX3

    Livija Deban;Remo Castro Russo;Marina Sironi;Federica Moalli

  • Rapid leukocyte integrin activation by chemokines.

    Carlo Laudanna;Ji Yun Kim;Gabriela Constantin;Eugene C. Butcher

  • Intraarterial Injection of Muscle-Derived Cd34+Sca-1+ Stem Cells Restores Dystrophin in mdx Mice

    Yuan Torrente;Jacques P. Tremblay;Federica Pisati;Marzia Belicchi

  • Molecular Mechanisms Involved in Lymphocyte Recruitment in Inflamed Brain Microvessels: Critical Roles for P-Selectin Glycoprotein Ligand-1 and Heterotrimeric Gi-Linked Receptors

    Laura Piccio;Barbara Rossi;Elio Scarpini;Carlo Laudanna

  • Neuroinflammation in Alzheimer disease

    Unknown

  • RhoA and ζ PKC Control Distinct Modalities of LFA-1 Activation by Chemokines: Critical Role of LFA-1 Affinity Triggering in Lymphocyte In Vivo Homing

    Cinzia Giagulli;Elio Scarpini;Linda Ottoboni;Shuh Narumiya

  • In vitro Models of Neurodegenerative Diseases.

    Anna Slanzi;Giulia Iannoto;Barbara Rossi;Elena Zenaro

  • Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule.

    Carlo Laudanna;Gabriela Constantin;P Baron;E Scarpini

  • Human adipose-derived mesenchymal stem cells systemically injected promote peripheral nerve regeneration in the mouse model of sciatic crush.

    Silvia Marconi;Giusy Castiglione;Ermanna Turano;Guido Bissolotti

  • Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability

    Beatriz G. Galvez;Maurilio Sampaolesi;Maurilio Sampaolesi;Silvia Brunelli;Silvia Brunelli;Diego Covarello

  • Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte–endothelial interactions

    Barbara Rossi;Stefano Angiari;Elena Zenaro;Simona Luciana Budui

  • Macrophage/microglial Ezh2 facilitates autoimmune inflammation through inhibition of Socs3

    Xingli Zhang;Yan Wang;Jia Yuan;Ni Li

  • CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules: a critical role for P-selectin glycoprotein ligand-1

    Luca Battistini;Laura Piccio;Barbara Rossi;Simona Bach

  • Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module.

    Matteo Bolomini-Vittori;Alessio Montresor;Cinzia Giagulli;Donald Staunton

Frequent Co-Authors

Eugene C. Butcher
Eugene C. Butcher Stanford University
Elio Scarpini
Elio Scarpini University of Milan
Corrado Priami
Corrado Priami University of Pisa
Marco A. Cassatella
Marco A. Cassatella University of Verona
Giorgio Berton
Giorgio Berton University of Verona
Filippo Rossi
Filippo Rossi University of Verona
Georges Bismuth
Georges Bismuth Université Paris Cité
Giovanni Delogu
Giovanni Delogu Catholic University of the Sacred Heart
Nereo Bresolin
Nereo Bresolin University of Milan

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