World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
28398
World Ranking
5467
National Ranking
2595

Overview

Obi L. Griffith is affiliated with Washington University in St. Louis in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a strong emphasis on cancer-related studies and genomic research.

The scientist has contributed extensively to various fields of study, including:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader domains, their specialized subfields comprise:

  • Molecular Biology
  • Cancer Research
  • Genetics
  • Immunology
  • Oncology

The main topics covered in their work involve:

  • Cancer Genomics and Diagnostics
  • Genomics and Rare Diseases
  • Immunotherapy and Immune Responses
  • Biomedical Text Mining and Ontologies
  • Genetic factors in colorectal cancer
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research

Obi L. Griffith's recent publications highlight contributions to cancer research, genomic databases, and immunotherapy. Selected papers include:

  • Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts, 2020, Nucleic Acids Research
  • Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial, 2020, Clinical Cancer Research
  • DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms, 2023, Nucleic Acids Research
  • GA4GH: International policies and standards for data sharing across genomic research and healthcare, 2021, Cell Genomics
  • pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens, 2020, Cancer Immunology Research

The scientist frequently collaborates with several coauthors, including:

  • Malachi Griffith
  • Arpad Danos
  • Alex H. Wagner
  • Jason Saliba
  • Zachary L. Skidmore

The publication venues where Obi L. Griffith has a strong presence include:

  • Cancer Genetics
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Clinical Cancer Research

Best Publications

  • The Genome Sequence of the SARS-associated Coronavirus

    Marco A. Marra;Steven J. M. Jones;Caroline R. Astell;Robert A. Holt

  • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

    Morin Rd;Johnson Na;Severson Tm;Mungall Aj

  • Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

    Gordon Robertson;Martin Hirst;Matthew Bainbridge;Misha Bilenky

  • DGIdb 3.0: a redesign and expansion of the drug-gene interaction database.

    Kelsy C Cotto;Alex H Wagner;Yang-Yang Feng;Susanna Kiwala

  • Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

    Shunqiang Li;Dong Shen;Jieya Shao;Robert Crowder

  • The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC)

    Daniela S. Gerhard;Lukas Wagner;Elise A. Feingold;Carolyn M. Shenmen

  • Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts.

    Sharon L Freshour;Susanna Kiwala;Kelsy C Cotto;Adam C Coffman

  • Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

    Dejan Juric;Pau Castel;Malachi Griffith;Obi L. Griffith

  • CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

    Malachi Griffith;Nicholas C. Spies;Kilannin Krysiak;Joshua F. McMichael

  • DGIdb: mining the druggable genome

    Malachi Griffith;Obi L Griffith;Adam C Coffman;James V Weible

  • SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

    Christopher A. Miller;Brian S. White;Nathan D. Dees;Malachi Griffith

  • DGIdb 2.0: mining clinically relevant drug-gene interactions.

    Alex H. Wagner;Adam C. Coffman;Benjamin J. Ainscough;Nicholas C. Spies

  • Alternative expression analysis by RNA sequencing.

    Malachi Griffith;Malachi Griffith;Obi L Griffith;Obi L Griffith;Jill Mwenifumbo;Rodrigo Goya

  • pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens.

    Jasreet Hundal;Beatriz M. Carreno;Allegra A. Petti;Gerald P. Linette

  • Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

    Jeffery M. Klco;Christopher A. Miller;Malachi Griffith;Allegra Petti

  • Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers.

    Obi L. Griffith;Adrienne Melck;Steven J.M. Jones;Sam M. Wiseman

  • Modeling precision treatment of breast cancer

    Anneleen Daemen;Anneleen Daemen;Anneleen Daemen;Obi L Griffith;Obi L Griffith;Obi L Griffith;Laura M Heiser;Laura M Heiser;Nicholas J Wang;Nicholas J Wang

  • ORegAnno: an open-access community-driven resource for regulatory annotation.

    Obi L. Griffith;Stephen B. Montgomery;Bridget Bernier;Bryan Chu

  • Mitelman Database (Chromosome Aberrations and Gene Fusions in Cancer)

    Malachi Griffith;Obi L. Griffith

  • Integration of the Drug-Gene Interaction Database (DGIdb) with open crowdsource efforts

    Sharon Freshour;Susanna Kiwala;Kelsy C. Cotto;Adam C. Coffman

Frequent Co-Authors

Malachi Griffith
Malachi Griffith Washington University in St. Louis
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Steven J.M. Jones
Steven J.M. Jones University of British Columbia
Joe W. Gray
Joe W. Gray Oregon Health & Science University
Robert S. Fulton
Robert S. Fulton Washington University in St. Louis
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital
David E. Larson
David E. Larson Washington University in St. Louis
Vincent Magrini
Vincent Magrini The Ohio State University
Todd A. Fehniger
Todd A. Fehniger Washington University in St. Louis
Catrina Fronick
Catrina Fronick Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Obi L. Griffith

Trending Scientists

Recently Published Articles