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Genetics

D-Index
48
Citations
24907
World Ranking
4019
National Ranking
460

Overview

Mark M. Iles is affiliated with the University of Leeds in the United Kingdom. Their research contributions span several fields including Medicine and Biochemistry, Genetics, and Molecular Biology, with significant work in Genetics, Molecular Biology, Oncology, Cell Biology, and Obstetrics and Gynecology.

The scientist's work focuses on key topics such as Genetic Associations and Epidemiology, melanin and skin pigmentation, Cutaneous Melanoma Detection and Management, Epigenetics and DNA Methylation, Gestational Diabetes Research and Management, Genomics and Chromatin Dynamics, and Skin Protection and Aging.

Mark M. Iles has published in multiple scientific venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • The American Journal of Human Genetics
  • British Journal of Dermatology
  • Human Molecular Genetics

Recent papers authored or co-authored by Mark M. Iles include:

  • Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility, 2020, Nature Genetics
  • Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma, 2020, Nature Communications
  • Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers, 2020, Nature Communications
  • A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization, 2021, Nature Communications
  • Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis, 2023, Journal of the American College of Cardiology

Frequent co-authors working alongside Mark M. Iles include:

  • Matthew H. Law
  • D. Timothy Bishop
  • Stuart MacGregor
  • Kevin M. Brown
  • Maria Teresa Landi

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Genomewide association analysis of coronary artery disease.

    Nilesh J. Samani;Jeanette Erdmann;Alistair S. Hall;Christian Hengstenberg

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Genome-wide association analysis identifies 20 loci that influence adult height

    M N Weedon;H Lango;C M Lindgren;C M Lindgren;C Wallace

  • Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

    G. Eiriksdottir;T. B. Harris;L. J. Launer;V. Gudnason

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

    Muredach P Reilly;Mingyao Li;Jing He;Jane F Ferguson

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Genome-wide association study identifies three loci associated with melanoma risk.

    D Timothy Bishop;Florence Demenais;Mark M Iles;Mark Harland

  • A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

    Matthias Heinig;Enrico Petretto;Chris Wallace;Leonardo Bottolo

  • Genome-wide association study identifies three new melanoma susceptibility loci

    Jennifer H. Barrett;Mark M. Iles;Mark Harland;John C. Taylor

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Yingchang Lu;Felix R Day;Stefan Gustafsson;Stefan Gustafsson;Martin L Buchkovich

  • Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

    Matthew H. Law;D. Timothy Bishop;Jeffrey E. Lee;Myriam Brossard

  • Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.

    Jiyeon Choi;Tongwu Zhang;Andrew Vu;Julien Ablain

  • What Can Genome-Wide Association Studies Tell Us about the Genetics of Common Disease?

    Mark M Iles

  • Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

    Stuart MacGregor;Grant W Montgomery;Jimmy Z Liu;Zhen Zhen Zhao

  • Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

    Maria Teresa Landi;D. Timothy Bishop;Stuart MacGregor

  • Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

    Paul Nioi;Asgeir Sigurdsson;Gudmar Thorleifsson;Hannes Helgason

  • Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis

    Daniel Freitag;Adam S. Butterworth;Peter Willeit;Joanna M M Howson

Frequent Co-Authors

Matthew Law
Matthew Law University of New South Wales
Stuart MacGregor
Stuart MacGregor QIMR Berghofer Medical Research Institute
Jennifer H. Barrett
Jennifer H. Barrett University of Leeds
Kevin M. Brown
Kevin M. Brown National Institutes of Health
D. Timothy Bishop
D. Timothy Bishop University of Leeds
Florence Demenais
Florence Demenais Université Paris Cité
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Maria Teresa Landi
Maria Teresa Landi National Institutes of Health
David L. Duffy
David L. Duffy QIMR Berghofer Medical Research Institute

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