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Immunology

D-Index
53
Citations
29706
World Ranking
3922
National Ranking
1796

Overview

Jianda Yuan is affiliated with MSD in the United States and primarily works in the field of Medicine with a focus on Oncology. Their research spans several subfields including Epidemiology, Radiology, Nuclear Medicine and Imaging, Pulmonary and Respiratory Medicine, and Immunology.

The main topics of Yuan's work include:

  • Cancer Immunotherapy and Biomarkers
  • Nonmelanoma Skin Cancer Studies
  • Cutaneous Melanoma Detection and Management
  • CAR-T cell therapy research
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Treatments and Mutations
  • Immunotherapy and Immune Responses

Yuan has published extensively, with notable recent papers including:

  • "Hallmarks of Resistance to Immune-Checkpoint Inhibitors," 2022, Cancer Immunology Research
  • "Pembrolizumab monotherapy versus chemotherapy in platinum-pretreated, recurrent or metastatic nasopharyngeal cancer (KEYNOTE-122): an open-label, randomized, phase III trial," 2022, Annals of Oncology
  • "Current strategies for intratumoural immunotherapy - Beyond immune checkpoint inhibition," 2021, European Journal of Cancer
  • "Biomarker-directed, pembrolizumab-based combination therapy in non-small cell lung cancer: phase 2 KEYNOTE-495/KeyImPaCT trial interim results," 2023, Nature Medicine
  • "Translational Biomarkers and Rationale Strategies to Overcome Resistance to Immune Checkpoint Inhibitors in Solid Tumors," 2020, Cancer treatment and research

Frequent publication venues for Yuan include:

  • Regular and Young Investigator Award Abstracts
  • arXiv (Cornell University)
  • Annals of Oncology
  • Journal of Clinical Oncology
  • Clinical Cancer Research

Yuan has collaborated with several coauthors on multiple occasions, with frequent collaborators being:

  • Burak Gümüşçü
  • Laurent Mortier
  • Åse Bratland
  • Mikhail Klochikhin
  • Michael Schenker

Best Publications

  • Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

    Naiyer A. Rizvi;Naiyer A. Rizvi;Matthew D. Hellmann;Matthew D. Hellmann;Alexandra Snyder;Alexandra Snyder;Pia Kvistborg

  • Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

    Alexandra Snyder;Vladimir Makarov;Taha Merghoub;Jianda Yuan

  • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

    Héctor Peinado;Maša Alečković;Simon Lavotshkin;Irina Matei

  • Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

    Michael A. Postow;Margaret K. Callahan;Margaret K. Callahan;Christopher A. Barker;Christopher A. Barker;Yoshiya Yamada;Yoshiya Yamada

  • Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

    Vinod P Balachandran;Michael J Cavnar;Shan Zeng;Zubin M Bamboat

  • Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab.

    Alexander Martens;Kilian Wistuba-Hamprecht;Marnix H Geukes Foppen;Jianda Yuan

  • Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial.

    Bradley C. Carthon;Jedd D. Wolchok;Jianda Yuan;Ashish Kamat

  • Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting lymphocyte count after 2 doses correlates with survival

    Geoffrey Y. Ku;Jianda Yuan;David B. Page;Sebastian E. A. Schroeder

  • CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

    Jianda Yuan;Sacha Gnjatic;Hao Li;Sarah Powel

  • Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab

    Jianda Yuan;Matthew Adamow;Brian A. Ginsberg;Teresa S. Rasalan

  • Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy.

    Weijie Ma;Weijie Ma;Barbara M. Gilligan;Jianda Yuan;Jianda Yuan;Tianhong Li

  • Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.

    David J. Chung;Marco Rossi;Emanuela Romano;Jennifer Ghith

  • Peripheral T cell receptor diversity is associated with clinical outcomes following ipilimumab treatment in metastatic melanoma.

    Michael A. Postow;Michael A. Postow;Manuarii Manuel;Phillip Wong;Jianda Yuan

  • Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

    Jianda Yuan;Priti S. Hegde;Raphael Clynes;Periklis G. Foukas;Periklis G. Foukas

  • A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.

    Heather L. McArthur;Adi Diab;David B. Page;Jianda Yuan

  • Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermal-interstitial or monocyte-derived dendritic cells.

    Gundrun Ratzinger;Jan Baggers;Maria A. de Cos;Jianda Yuan

  • Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

    Sylvia Janetzki;Katherine S. Panageas;Leah Ben-Porat;Jean Boyer

  • Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy

    Derek Ng Tang;Yu Shen;Jingjing Sun;Sijin Wen

  • Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

    Miguel-Angel Perales;Miguel-Angel Perales;Jenna D. Goldberg;Jenna D. Goldberg;Jianda Yuan;Guenther Koehne;Guenther Koehne

  • Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype

    Daniel Hirschhorn-Cymerman;Sadna Budhu;Shigehisa Kitano;Cailian Liu

  • Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia.

    Peter G. Maslak;Tao Dao;Lee M. Krug;Suzanne Chanel

Frequent Co-Authors

Jedd D. Wolchok
Jedd D. Wolchok Cornell University
James P. Allison
James P. Allison The University of Texas MD Anderson Cancer Center
Michael A. Postow
Michael A. Postow Memorial Sloan Kettering Cancer Center
Katherine S. Panageas
Katherine S. Panageas Memorial Sloan Kettering Cancer Center
Larry Norton
Larry Norton Memorial Sloan Kettering Cancer Center
Clifford A. Hudis
Clifford A. Hudis Memorial Sloan Kettering Cancer Center
Paul B. Chapman
Paul B. Chapman Memorial Sloan Kettering Cancer Center
Alan N. Houghton
Alan N. Houghton Memorial Sloan Kettering Cancer Center
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Adi Diab
Adi Diab The University of Texas MD Anderson Cancer Center

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