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Nobuhiko Kayagaki

Nobuhiko Kayagaki

Genentech
United States

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Biology and Biochemistry 70 6852 6319 3160 2837 113 30473

Nobuhiko Kayagaki publications per year

The chart shows the history of publications by Nobuhiko Kayagaki between 1994 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Nobuhiko Kayagaki published across 32 years, from 1994 to 2025, averaging 3.9 papers a year. Output peaked at 17 publications in 1997. 9 of the 124 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1994 to 2025. Vertical axis: number of publications, 0 to 17. Peak 17 publications in 1997. 1994: 2 publications 1995: 1 publication 1996: 7 publications 1997: 17 publications 1998: 7 publications 1999: 14 publications 2000: 6 publications 2001: 9 publications 2002: 8 publications 2003: 2 publications 2004: 1 publication 2005: 2 publications 2006: 0 publications 2007: 3 publications 2008: 0 publications 2009: 0 publications 2010: 2 publications 2011: 2 publications 2012: 3 publications 2013: 2 publications 2014: 1 publication 2015: 4 publications 2016: 3 publications 2017: 2 publications 2018: 3 publications 2019: 3 publications 2020: 0 publications 2021: 7 publications 2022: 0 publications 2023: 4 publications 2024: 3 publications 2025: 6 publications
1994 2025

124 publications in total across all disciplines

View publications per year as a table
Nobuhiko Kayagaki: publications per year, 1994 to 2025
Year Publications
1994 2
1995 1
1996 7
1997 17
1998 7
1999 14
2000 6
2001 9
2002 8
2003 2
2004 1
2005 2
2006 0
2007 3
2008 0
2009 0
2010 2
2011 2
2012 3
2013 2
2014 1
2015 4
2016 3
2017 2
2018 3
2019 3
2020 0
2021 7
2022 0
2023 4
2024 3
2025 6
Total 124
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Nobuhiko Kayagaki publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Nobuhiko Kayagaki sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 107–116 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 113 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704 113
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315
317–326 296
327–336 261
337–346 240
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
Download as CSV

Nobuhiko Kayagaki D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Nobuhiko Kayagaki sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 70–71 D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 70 D-Index — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714 70
72–73 709
74–75 596
76–77 512
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98
Download as CSV

Overview

Nobuhiko Kayagaki is a researcher affiliated with Genentech in the United States. Their academic work primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions in Medicine. Within these domains, their subfields of study include Molecular Biology, Immunology, Epidemiology, Biophysics, and Hematology.

The scientist's publications cover several key topics, including Inflammasome and immune disorders, Cell death mechanisms and regulation, Heme Oxygenase-1 and Carbon Monoxide, Immune Response and Inflammation, Autophagy in Disease and Therapy, Autoimmune and Inflammatory Disorders Research, and Gout, Hyperuricemia, Uric Acid.

Notable recent papers authored or co-authored by Kayagaki include:

  • "NINJ1 mediates plasma membrane rupture during lytic cell death" (2021, Nature)
  • "Cell death" (2024, Cell)
  • "Dying cells fan the flames of inflammation" (2021, Science)
  • "Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection" (2021, Cell Host & Microbe)
  • "Selective activation of PFKL suppresses the phagocytic oxidative burst" (2021, Cell)

Frequent co-authors in their research include Vishva M. Dixit, Kim Newton, Opher S. Kornfeld, Irma B. Stowe, and Joshua D. Webster. Kayagaki has collaborated extensively with these researchers, indicating a networked approach to their work.

The main publication venues for Kayagaki's research are:

  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Nature Biotechnology
  • Science

Overall, Kayagaki's research contributions center on molecular mechanisms governing inflammation and immune response, with a significant focus on understanding cell death pathways and their implications for immune disorders.

Best Publications

  • Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

    Nobuhiko Kayagaki;Irma B. Stowe;Bettina L. Lee;Karen O’Rourke

  • Non-canonical inflammasome activation targets caspase-11

    Nobuhiko Kayagaki;Søren Warming;Mohamed Lamkanfi;Lieselotte Vande Walle

  • Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

    Nobuhiko Kayagaki;Michael T. Wong;Irma B. Stowe;Sree Ranjani Ramani

  • IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

    Eugene Varfolomeev;John W. Blankenship;Sarah M. Wayson;Anna V. Fedorova

  • Metalloproteinase-mediated release of human Fas ligand.

    N Kayagaki;A Kawasaki;T Ebata;H Ohmoto

  • Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.

    Pontus Orning;Pontus Orning;Dan Weng;Dan Weng;Kristian Starheim;Kristian Starheim;Dmitry Ratner

  • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth;Nobuhiko Kayagaki

  • GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

    Robin A. Aglietti;Alberto Estevez;Aaron Gupta;Monica Gonzalez Ramirez

  • NINJ1 mediates plasma membrane rupture during lytic cell death

    Nobuhiko Kayagaki;Opher S. Kornfeld;Bettina L. Lee;Irma B. Stowe

  • Type I Interferons (IFNs) Regulate Tumor Necrosis Factor–related Apoptosis-inducing Ligand (TRAIL) Expression on Human T Cells: A Novel Mechanism for the Antitumor Effects of Type I IFNs

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Hiroshi Eto

  • Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Contributes to Interferon γ–Dependent Natural Killer Cell Protection from Tumor Metastasis

    Mark J. Smyth;Erika Cretney;Kazuyoshi Takeda;Robert H. Wiltrout

  • Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

    Kazuyoshi Takeda;Mark J. Smyth;Erika Cretney;Yoshihiro Hayakawa

  • BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

    Nobuhiko Kayagaki;Minhong Yan;Dhaya Seshasayee;Hua Wang

  • Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

    Petr Broz;Thomas Ruby;Kamila Belhocine;Donna M. Bouley

  • Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

    Jonathan W. Jones;Nobuhiko Kayagaki;Petr Broz;Thomas Henry

  • Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

    Etienne Meunier;Mathias S. Dick;Roland F. Dreier;Nura Schürmann

  • DUBA: a deubiquitinase that regulates type I interferon production.

    Nobuhiko Kayagaki;Qui Phung;Salina Chan;Ruchir Chaudhari

  • Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda

  • Antitumor effect of locally produced CD95 ligand

    Ken-Ichiro Seino;Nobuhiko Kayagaki;Ko Okumura;Hideo Yagita

  • Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL.

    K Ando;K Hiroishi;T Kaneko;T Moriyama

Frequent Co-Authors

Hideo Yagita
Hideo Yagita Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Kazuyoshi Takeda
Kazuyoshi Takeda Juntendo University
Haruki Okamura
Haruki Okamura Hyogo College of Medicine
Hiroko Tsutsui
Hiroko Tsutsui Hyogo College of Medicine
Kenji Nakanishi
Kenji Nakanishi Hyogo College of Medicine
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Hisaya Akiba
Hisaya Akiba Juntendo University
Tetsuji Kobata
Tetsuji Kobata Tokyo Medical and Dental University
Toshikazu Shirai
Toshikazu Shirai Juntendo University

External Links

Personal website of Nobuhiko Kayagaki

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Best Scientists Citing Nobuhiko Kayagaki

Hideo Yagita

Hideo Yagita

Juntendo University

Publications: 151

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 103

Ko Okumura

Ko Okumura

Juntendo University

Publications: 71

Kenji Nakanishi

Kenji Nakanishi

Hyogo College of Medicine

Publications: 56

Hiroko Tsutsui

Hiroko Tsutsui

Hyogo College of Medicine

Publications: 50

Kazuyoshi Takeda

Kazuyoshi Takeda

Juntendo University

Publications: 47

Thomas S. Griffith

Thomas S. Griffith

University of Minnesota

Publications: 46

Haruki Okamura

Haruki Okamura

Hyogo College of Medicine

Publications: 39

Linda C. Burkly

Linda C. Burkly

Biogen (United States)

Publications: 35

Henning Walczak

Henning Walczak

University College London

Publications: 33

Myung-Shik Lee

Myung-Shik Lee

Yonsei University

Publications: 33

James L.M. Ferrara

James L.M. Ferrara

Icahn School of Medicine at Mount Sinai

Publications: 31

Jerry Y. Niederkorn

Jerry Y. Niederkorn

The University of Texas Southwestern Medical Center

Publications: 31

Thirumala-Devi Kanneganti

Thirumala-Devi Kanneganti

St. Jude Children's Research Hospital

Publications: 30

Yoshihiro Hayakawa

Yoshihiro Hayakawa

Aichi Institute of Technology

Publications: 29

Andrew D. Badley

Andrew D. Badley

Mayo Clinic

Publications: 28

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