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Biology and Biochemistry

D-Index
73
Citations
16023
World Ranking
6050
National Ranking
2848

Overview

Mingjiang Xu is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with a significant focus on subfields such as molecular biology, hematology, and cancer research.

Their work concentrates on specific topics including acute myeloid leukemia research, epigenetics and DNA methylation, RNA modifications and cancer, cancer-related molecular mechanisms, RNA research and splicing, cancer-related gene regulation, and histone deacetylase inhibitors research.

Key recent publications by Mingjiang Xu include the following:

  • RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis, 2024, Nature
  • TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal, 2023, Cell stem cell
  • HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia, 2022, Molecular Cell
  • HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia, 2021, Nature Communications
  • Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies, 2020, Journal of Hematology & Oncology

Mingjiang Xu frequently publishes in several scientific venues, including:

  • Blood
  • Molecular Cell
  • Nature Communications
  • Cell stem cell
  • Leukemia

Their collaborative network includes several frequent co-authors, notably:

  • Feng-Chun Yang
  • Ganqian Zhu
  • Huacheng Luo
  • Shi Chen

Best Publications

  • Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.

    Zhe Li;Xiaoqiang Cai;Chen Leng Cai;Jiapeng Wang

  • Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

    Luisa Cimmino;Igor Dolgalev;Yubao Wang;Akihide Yoshimi

  • Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

    Meelad M. Dawlaty;Achim Breiling;Thuc Le;Günter Raddatz

  • NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

    Yael Costa;Junjun Ding;Thorold W. Theunissen;Francesco Faiola

  • Hepatocytes: a key cell type for innate immunity

    Zhou Zhou;Ming-Jiang Xu;Bin Gao

  • Resident c-kit(+) cells in the heart are not cardiac stem cells.

    Nishat Sultana;Lu Zhang;Jianyun Yan;Jiqiu Chen

  • Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.

    Shu Xing;Tina Ho Wanting;Wanming Zhao;Junfeng Ma

  • TET1 plays an essential oncogenic role in MLL-rearranged leukemia

    Hao Huang;Xi Jiang;Zejuan Li;Yuanyuan Li

  • Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis

    Stefan O. Ciurea;Delwin Merchant;Nadim Mahmud;Takefumi Ishii

  • Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo.

    Ming-Ming Zhao;Ming-Jiang Xu;Yan Cai;Gexin Zhao

  • MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils

    Man Li;Man Li;Yong He;Zhou Zhou;Teresa Ramirez

  • Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells.

    Sahoko Matsuoka;Sahoko Matsuoka;Sahoko Matsuoka;Kohichiro Tsuji;Kohichiro Tsuji;Kohichiro Tsuji;Hiroaki Hisakawa;Hiroaki Hisakawa;Hiroaki Hisakawa;Ming Jiang Xu;Ming Jiang Xu;Ming Jiang Xu

  • Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis

    Taisei Kinoshita;Takashi Sekiguchi;Ming Jiang Xu;Yoshiaki Ito

  • Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release

    Xiao-Yan Dai;Ming-Ming Zhao;Yan Cai;Qing-Cong Guan

  • Stimulation of Mouse and Human Primitive Hematopoiesis by Murine Embryonic Aorta-Gonad-Mesonephros–Derived Stromal Cell Lines

    Ming Jiang Xu;Kohichiro Tsuji;Kohichiro Tsuji;Takahiro Ueda;Takahiro Ueda;Yoh Suke Mukouyama;Yoh Suke Mukouyama

  • The presence of JAK2V617F mutation in the liver endothelial cells of patients with Budd-Chiari syndrome.

    Selcuk Sozer;Maria Isabel Fiel;Thomas Schiano;Mingjiang Xu

  • Short- or long-term high fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: an important role for CXCL1

    Binxia Chang;Ming-Jiang Xu;Zhou Zhou;Yan Cai

  • Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein

    Yasunori Tanaka;Ichiro Naruse;Takuya Hongo;Ming Jiang Xu

  • Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice.

    Jiapeng Wang;Zhaomin Li;Yongzheng He;Feng Pan;Feng Pan

  • Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy.

    Ding Ai;Wei Pang;Nan Li;Ming Xu

Frequent Co-Authors

Feng Chun Yang
Feng Chun Yang The University of Texas Health Science Center at San Antonio
Bin Gao
Bin Gao National Institutes of Health
Ronald Hoffman
Ronald Hoffman Mount Sinai Hospital
Stephen D. Nimer
Stephen D. Nimer University of Miami
Tatsutoshi Nakahata
Tatsutoshi Nakahata Kyoto University
Kohichiro Tsuji
Kohichiro Tsuji University of Tokyo
Zhizhuang Joe Zhao
Zhizhuang Joe Zhao University of Oklahoma Health Sciences Center
Peng Jin
Peng Jin Emory University
Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Helmut Hanenberg
Helmut Hanenberg University of Duisburg-Essen

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