World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
52
Citations
13157
World Ranking
2417
National Ranking
56

Overview

Serena Zacchigna is affiliated with the International Centre for Genetic Engineering and Biotechnology in Italy and has a significant body of work in the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans a variety of subfields including cardiology and cardiovascular medicine, molecular biology, surgery, infectious diseases, and pulmonary and respiratory medicine.

Their published work frequently appears in notable journals, with substantial contributions to Cardiovascular Research, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, International Journal of Molecular Sciences, and European Journal of Heart Failure.

Serena Zacchigna has authored or co-authored numerous papers addressing a diverse range of topics. Some of their recent publications include:

  • Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology, 2020, EBioMedicine
  • Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function, 2020, Cardiovascular Research
  • SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence, 2023, Nature Cell Biology
  • Prognostic Prediction of Genotype vs Phenotype in Genetic Cardiomyopathies, 2022, Journal of the American College of Cardiology
  • Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart, 2020, Cardiovascular Research

Their research covers a broad set of specialized topics, including:

  • Cardiomyopathy and Myosin Studies
  • Cardiac Fibrosis and Remodeling
  • Tissue Engineering and Regenerative Medicine
  • COVID-19 Clinical Research Studies
  • Congenital Heart Defects Research
  • SARS-CoV-2 and COVID-19 Research
  • RNA Research and Splicing

They have collaborated frequently with other researchers such as Mauro Giacca, Simone Vodret, Andrea Colliva, Roman Vuerich, and Lorena Zentilin, collectively contributing to numerous publications.

Best Publications

  • Functional screening identifies miRNAs inducing cardiac regeneration

    Ana Eulalio;Miguel Mano;Matteo Dal Ferro;Matteo Dal Ferro;Lorena Zentilin

  • Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels

    Christian Fischer;Bart Jonckx;Massimiliano Mazzone;Serena Zacchigna

  • The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.

    Bao N. Puente;Wataru Kimura;Shalini A. Muralidhar;Jesung Moon

  • Modification of kidney barrier function by the urokinase receptor

    Changli Wei;Clemens C. Möller;Mehmet M. Altintas;Jing Li

  • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

    Julián Aragonés;Martin Schneider;Martin Schneider;Martin Schneider;Katie Van Geyte;Katie Van Geyte;Peter Fraisl;Peter Fraisl

  • Neurovascular signalling defects in neurodegeneration.

    Serena Zacchigna;Diether Lambrechts;Peter Carmeliet

  • MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

    Khatia Gabisonia;Giulia Prosdocimo;Giovanni Donato Aquaro;Lucia Carlucci

  • Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo

    Nikola Arsic;Serena Zacchigna;Lorena Zentilin;Genaro Ramirez-Correa

  • Virus-mediated gene delivery for human gene therapy.

    Mauro Giacca;Serena Zacchigna

  • Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

    Rossana Bussani;Edoardo Schneider;Lorena Zentilin;Chiara Collesi

  • Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.

    Sara Van de Veire;Ingeborg Stalmans;Femke Heindryckx;Hajimu Oura

  • VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond.

    M Giacca;S Zacchigna

  • Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

    Stephane Heymans;Maarten F. Corsten;Wouter Verhesen;Paolo Carai

  • Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

    Lorena Zentilin;Sabrina Tafuro;Sabrina Tafuro;Serena Zacchigna;Serena Zacchigna;Nikola Arsic;Nikola Arsic

  • Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction

    Pierluigi Lesizza;Giulia Prosdocimo;Valentina Martinelli;Gianfranco Sinagra

  • Systemic Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Delivery Shows Antiatherosclerotic Activity in Apolipoprotein E–Null Diabetic Mice

    Paola Secchiero;Riccardo Candido;Federica Corallini;Serena Zacchigna

  • Loss of the Cholesterol-Binding Protein Prominin-1/CD133 Causes Disk Dysmorphogenesis and Photoreceptor Degeneration

    Serena Zacchigna;Hideyasu Oh;Michaela Wilsch-Bräuninger;Ewa Missol-Kolka

  • In Vivo Activation of a Conserved MicroRNA Program Induces Mammalian Heart Regeneration

    Aitor Aguirre;Nuria Montserrat;Serena Zacchigna;Emmanuel Nivet

  • Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

    Lorena Zentilin;Uday Puligadda;Vincenzo Lionetti;Serena Zacchigna

  • Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743))

    Bao N. Puente;Wataru Kimura;Shalini A. Muralidhar;Jesung Moon

Frequent Co-Authors

Mauro Giacca
Mauro Giacca King's College London
Lorena Zentilin
Lorena Zentilin International Centre for Genetic Engineering and Biotechnology
Gianfranco Sinagra
Gianfranco Sinagra University of Trieste
Stephane Heymans
Stephane Heymans Maastricht University
Sergio Crovella
Sergio Crovella Qatar University
Thomas Thum
Thomas Thum Hannover Medical School

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