His main research concerns Transcription factor, NF-κB, Signal transduction, IκB kinase and Cell biology. His Transcription factor research includes elements of Proinflammatory cytokine, Inflammation and Regulation of gene expression. His studies in NF-κB integrate themes in fields like Transcription and Immune system.
His study in Signal transduction is interdisciplinary in nature, drawing from both Tumor necrosis factor alpha, Immunology and Cancer research. Michael J. May has included themes like Fibrosis, Endocrinology and Kinase in his IκB kinase study. His is involved in several facets of Cell biology study, as is seen by his studies on I-Kappa-B Kinase and CHUK.
Michael J. May spends much of his time researching Cell biology, IκB kinase, Signal transduction, Transcription factor and NF-κB. His work on I-Kappa-B Kinase and Phosphorylation as part of general Cell biology research is frequently linked to Binding domain, bridging the gap between disciplines. His IκB kinase study integrates concerns from other disciplines, such as IκBα, Molecular biology, Protein subunit and Kinase.
His Signal transduction study also includes
Cell biology, Transcription factor, NFAT, breakpoint cluster region and Cell are his primary areas of study. His Cell biology study focuses mostly on IκB kinase and Signal transduction. He interconnects Embryonic stem cell, Retrovirus, Transduction, Chimeric antigen receptor and Kinase in the investigation of issues within Signal transduction.
His Transcription factor study combines topics from a wide range of disciplines, such as Gene expression and Immune system. Within one scientific family, Michael J. May focuses on topics pertaining to T-cell receptor under NFAT, and may sometimes address concerns connected to NF-κB, Receptor, Jurkat cells and IκBα. In his study, Protein kinase B is strongly linked to Cell cycle, which falls under the umbrella field of breakpoint cluster region.
Michael J. May mainly investigates IκB kinase, Cell biology, Immunology, ORAI1 and T-cell receptor. His IκB kinase research is multidisciplinary, incorporating perspectives in Innate immune system, Innate lymphoid cell, Immunity, Interleukin 22 and Thymic stromal lymphopoietin. His research in Cell biology intersects with topics in Citrobacter rodentium and RAR-related orphan receptor gamma.
The concepts of his Immunology study are interwoven with issues in Carcinogenesis and CD11c. His ORAI1 research encompasses a variety of disciplines, including NFAT, IκBα, Transcription factor, T cell and Jurkat cells.
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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
Sankar Ghosh;Michael J. May;Elizabeth B. Kopp.
Annual Review of Immunology (1998)
Signal transduction through NF-κB
Michael J May;Sankar Ghosh.
Immunology Today (1998)
The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1
Haihong Zhong;Michael J May;Eijiro Jimi;Sankar Ghosh.
Molecular Cell (2002)
Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex
Michael J. May;Fulvio D'Acquisto;Lisa A. Madge;Judith Glöckner.
Science (2000)
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
Colby Zaph;Amy E. Troy;Betsy C. Taylor;Lisa D. Berman-Booty.
Nature (2007)
Selective inhibition of NF-|[kappa]|B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo
Eijiro Jimi;Eijiro Jimi;Kazuhiro Aoki;Hiroaki Saito;Fulvio D'Acquisto.
Nature Medicine (2004)
Rel/NF-κB and IκB proteins: an overview
Michael J. May;Sankar Ghosh.
Seminars in Cancer Biology (1997)
Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies.
Fulvio D'Acquisto;Michael J. May;Sankar Ghosh.
Molecular Interventions (2002)
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
Fiona Oakley;Muriel Meso;John P. Iredale;Karen Green.
Gastroenterology (2005)
The IκB kinase complex: master regulator of NF-κB signaling
Laura A. Solt;Michael J. May.
Immunologic Research (2008)
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