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Alain Israël

Alain Israël

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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Molecular Biology

D-Index
83
Citations
30671
World Ranking
892
National Ranking
25

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2000 - Member of Academia Europaea
  • 1989 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Alain Israël is affiliated with the Institut Pasteur in France and has contributed to research primarily in the fields of infectious diseases, parasitology, and ecology, evolution, behavior, and systematics. Their research work frequently covers topics related to viral infections and vectors as well as vector-borne infectious and animal diseases.

Their recent papers include the following:

  • Molecular screening for blood pathogens in synanthropic Pipistrellus bats in Spain reveals novel and human-related hemoplasmas, 2025, Comparative Immunology Microbiology and Infectious Diseases
  • Author Correction: TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2, 2025, Nature

Frequent co-authors in their publications include Javier Millán, Paula Santibáñez, Luís V. Monteagudo, Susana P Veloso Soares, and Ruth Rodríguez-Pastor.

Publication venues where their work appears regularly include:

  • Comparative Immunology Microbiology and Infectious Diseases
  • Nature

Alain Israël's research emphasizes the study of diseases transmitted by vectors, particularly focusing on viral infections and their impact on animals and human populations. The combination of subfields in parasitology and infectious diseases highlights their interdisciplinary approach to understanding complex biological interactions.

Throughout their career, they have been recognized with awards such as the Member of Academia Europaea in 2000 and the Fellowship from the John Simon Guggenheim Memorial Foundation in 1989.

Best Publications

  • Signalling downstream of activated mammalian Notch.

    Sophie Jarriault;Christel Brou;Frédérique Logeat;Eric H. Schroeter

  • A Novel Proteolytic Cleavage Involved in Notch Signaling: The Role of the Disintegrin-Metalloprotease TACE

    Christel Brou;Frédérique Logeat;Neetu Gupta;Christine Bessia

  • The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.

    Andrew Kovalenko;Christine Chable-Bessia;Giuseppina Cantarella;Giuseppina Cantarella;Alain Israël

  • Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

    Shoji Yamaoka;Gilles Courtois;Christine Bessia;Simon T Whiteside

  • The Notch1 receptor is cleaved constitutively by a furin-like convertase

    Frédérique Logeat;Christine Bessia;Christel Brou;Odile LeBail

  • The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

    Mark Kieran;Volker Blank;Frédérique Logeat;Joël Vandekerckhove

  • The IKK Complex, a Central Regulator of NF-κB Activation

    Alain Israël

  • Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium.

    Asmae Smahi;G. Courtois;P. Vabres;S. Yamaoka

  • X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.

    Rainer Döffinger;Asma Smahi;Christine Bessia;Frédéric Geissmann

  • The IKK complex: an integrator of all signals that activate NF-κB?

    Alain Israël

  • I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF‐κB activity

    Simon T. Whiteside;Jean‐Charles Epinat;Nancy R. Rice;Alain Israël

  • The precursor of NF-κB p50 has IκB-like functions

    N.R. Rice;M.L. MacKichan;M.L. MacKichan;A. Israël

  • NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

    Marc Schmidt-Supprian;Wilhelm Bloch;Gilles Courtois;Klaus Addicks

  • TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

    Manolis Pasparakis;Gilles Courtois;Martin Hafner;Martin Hafner;Marc Schmidt-Supprian;Marc Schmidt-Supprian

  • Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.

    Neetu Gupta-Rossi;Odile Le Bail;Hedva Gonen;Christel Brou

  • NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

    Volker Blank;Philippe Kourilsky;Alain Israël

  • IκB proteins: structure, function and regulation

    Simon T. Whiteside;Alain Israël

  • Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family.

    O Le Bail;R Schmidt-Ullrich;A Israël

  • Detailed analysis of the mouse H-2Kb promoter: enhancer-like sequences and their role in the regulation of class I gene expression

    Akinori Kimura;Alain Israël;Odile Le Bail;Philippe Kourilsky

  • Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

    Sophie Jarriault;Odile Le Bail;Estelle Hirsinger;Olivier Pourquié

Frequent Co-Authors

Philippe Kourilsky
Philippe Kourilsky Collège de France
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Laurent Abel
Laurent Abel Université Paris Cité
Michel Véron
Michel Véron Institut Pasteur
Shoji Yamaoka
Shoji Yamaoka Tokyo Medical and Dental University
Guido Kroemer
Guido Kroemer Université Paris Cité
Aaron Ciechanover
Aaron Ciechanover Technion – Israel Institute of Technology
Eugenia Morselli
Eugenia Morselli San Sebastián University
Alan L. Schwartz
Alan L. Schwartz Washington University in St. Louis

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