Margarita López-Trascasa

Overview

Best Publications

• Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond.

  Angelo Agostoni;Emel Aygören-Pürsün;Karen E. Binkley;Alvaro Blanch

  876
  Citations

• The human complement factor H: functional roles, genetic variations and disease associations.

  Santiago Rodrı́guez de Córdoba;Jorge Esparza-Gordillo;Elena Goicoechea de Jorge;Margarita Lopez-Trascasa

  747
  Citations

• Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

  Elena Goicoechea de Jorge;Claire L. Harris;Jorge Esparza-Gordillo;Luis Carreras

  534
  Citations

• Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32

  Jorge Esparza-Gordillo;Elena Goicoechea de Jorge;Alfonso Buil;Luis Carreras Berges

  341
  Citations

• Hereditary angioedema due to C1 inhibitor deficiency: patient registry and approach to the prevalence in Spain.

  Olga Roche;Alvaro Blanch;Teresa Caballero;Noelia Sastre

  279
  Citations

• Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome

  Pilar Sánchez-Corral;Pilar Sánchez-Corral;David Pérez-Caballero;Olatz Huarte;Ari M. Simckes

  275
  Citations

• Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome.

  Cynthia Abarrategui-Garrido;Rubén Martínez-Barricarte;Margarita López-Trascasa;Santiago Rodríguez de Córdoba

  260
  Citations

• The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models.

  Rebecca E. Saunders;Cynthia Abarrategui-Garrido;Véronique Frémeaux-Bacchi;Elena Goicoechea de Jorge

  252
  Citations

• High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis

  Marten Trendelenburg;Margarita Lopez-Trascasa;Eliska Potlukova;Solange Moll

  238
  Citations

• Functional analysis in serum from atypical Hemolytic Uremic Syndrome patients reveals impaired protection of host cells associated with mutations in factor H

  P Sánchez-Corral;C González-Rubio;S Rodríguez de Córdoba;M López-Trascasa

  214
  Citations

• IgA glomerulonephritis (Berger's disease): evidence of high serum levels of polymeric IgA.

  M L Trascasa;J Egido;J Sancho;L Hernando

  157
  Citations

• Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree.

  Jorge Esparza-Gordillo;Elena Goicoechea de Jorge;Cynthia Abarrategui Garrido;Luis Carreras

  155
  Citations

• Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, genetics, clinical symptoms, and diagnosis.

  T Caballero;M L Baeza;R Cabañas;A Campos

  151
  Citations

• Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part II. Treatment, follow-up, and special situations.

  T Caballero;M L Baeza;R Cabañas;A Campos

  137
  Citations

• Metallopeptidase activities in hereditary angioedema: Effect of androgen prophylaxis on plasma aminopeptidase P

  Christian Drouet;Anik Désormeaux;Josée Robillard;Denise Ponard

  129
  Citations

• Elevated factor H-related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy.

  Agustín Tortajada;Eduardo Gutiérrez;Elena Goicoechea de Jorge;Jaouad Anter

  127
  Citations

• Functional C1-inhibitor diagnostics in hereditary angioedema: Assay evaluation and recommendations

  Ineke G A Wagenaar-Bos;Christian Drouet;Emel Aygören-Pursun;Konrad Bork

  121
  Citations

• Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation

  Danielle Paixao-Cavalcante;Margarita Lopez-Trascasa;Lillemor Melander Skattum;Patricia C. Giclas

  113
  Citations

• First case of homozygous C1 inhibitor deficiency.

  Alvaro Blanch;Olga Roche;Ignacio Urrutia;Pedro Gamboa

  94
  Citations

• Complement Mutations in Diacylglycerol Kinase-ε–Associated Atypical Hemolytic Uremic Syndrome

  Daniel Sánchez Chinchilla;Sheila Pinto;Bernd Hoppe;Marta Adragna

  92
  Citations

• A possible common pathogenesis of the mesangial IgA glomerulonephritis in patients with Berger's disease and Schönlein-Henoch syndrome.

  J Egido;J Sancho;F Mampaso;M Lopez Trascasa

  87
  Citations

• Anti-IgA antibodies in selective IgA deficiency and in primary immunodeficient patients treated with γ-globulin

  Antonio Ferreira;Maria Cruz Garcia Rodriguez;Margarita Lopez-Trascasa;Dora Pascual Salcedo

  84
  Citations

• Complement factor I deficiency: a not so rare immune defect: characterization of new mutations and the first large gene deletion

  María Alba-Domínguez;Alberto López-Lera;Sofía Garrido;Pilar Nozal

  48
  Citations