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Déborah Bourc'his

Déborah Bourc'his

D-Index & Metrics

Genetics

D-Index
47
Citations
16984
World Ranking
4085
National Ranking
212

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Déborah Bourc'his is affiliated with the Institute Curie in France. Their research spans across biochemistry, genetics, and molecular biology, with a significant focus on medicine. The main fields of study include molecular biology and genetics alongside pediatrics, perinatology, child health, and public health.

The scientist's work primarily addresses topics such as epigenetics and DNA methylation, CRISPR and genetic engineering, prenatal screening and diagnostics, RNA modifications and cancer, genetic syndromes and imprinting, genetics and neurodevelopmental disorders, and reproductive biology and fertility.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Nature Structural & Molecular Biology, Nature, and Human Reproduction.

Coauthors regularly collaborating with Déborah Bourc'his are Aurélie Teissandier, Patricia Fauque, Julie Barberet, Magali Guilleman, and Nicolas Servant.

Recent papers reflect a focus on epigenetic regulation and reproductive biology:

  • "m6A RNA methylation regulates the fate of endogenous retroviruses," 2021, Nature
  • "DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis," 2022, Nature Genetics
  • "Do assisted reproductive technologies and in vitro embryo culture influence the epigenetic control of imprinted genes and transposable elements in children?", 2020, Human Reproduction
  • "Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes," 2020, Molecular Biology and Evolution
  • "The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates," 2022, eLife

Bourc'his has been recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Dnmt3L and the establishment of maternal genomic imprints.

    Déborah Bourc'his;Guo-Liang Xu;Chyuan-Sheng Lin;Brooke Bollman

  • The diverse roles of DNA methylation in mammalian development and disease

    Maxim V. C. Greenberg;Deborah Bourc’his

  • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene.

    Guo-Liang Xu;Timothy H. Bestor;Déborah Bourc'his;Chih-Lin Hsieh

  • Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L.

    Déborah Bourc'his;Timothy H. Bestor

  • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.

    Alexei A. Aravin;Alexei A. Aravin;Ravi Sachidanandam;Ravi Sachidanandam;Deborah Bourc'his;Christopher Schaefer;Christopher Schaefer

  • MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline.

    Michelle A. Carmell;Angélique Girard;Angélique Girard;Henk J.G. van de Kant;Deborah Bourc'his

  • Chromosome methylation patterns during mammalian preimplantation development

    Nathalie Rougier;Déborah Bourc’his;Denise Molina Gomes;Alain Niveleau

  • Genomic Imprinting and Physiological Processes in Mammals.

    Valter Tucci;Anthony R. Isles;Gavin Kelsey;Gavin Kelsey;Anne C. Ferguson-Smith

  • Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos

    D Bourc'his;D Le Bourhis;D Patin;A Niveleau

  • The DNA methyltransferase DNMT3C protects male germ cells from transposon activity.

    Joan Barau;Aurélie Teissandier;Aurélie Teissandier;Natasha Zamudio;Stéphanie Roy

  • An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

    Marius Walter;Aurélie Teissandier;Raquel Pérez-Palacios;Déborah Bourc'his

  • Epigenetic decisions in mammalian germ cells

    Christopher B. Schaefer;Steen K. T. Ooi;Timothy H. Bestor;Déborah Bourc'his

  • A small-RNA perspective on gametogenesis, fertilization, and early zygotic development.

    Déborah Bourc’his;Olivier Voinnet;Olivier Voinnet

  • Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

    Shantha K. Mahadevaiah;Déborah Bourc'his;Dirk G. de Rooij;Dirk G. de Rooij;Timothy H. Bestor

  • Small RNA guides for de novo DNA methylation in mammalian germ cells

    Alexei A. Aravin;Déborah Bourc’his

  • Transposable elements in the mammalian germline: a comfortable niche or a deadly trap?

    N Zamudio;D Bourc'his

  • m6A RNA methylation regulates the fate of endogenous retroviruses

    Tomasz Chelmicki;Emeline Roger;Aurélie Teissandier;Mathilde Dura

  • Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2

    Tadashi Kondo;Miroslav P. Bobek;Rork Kuick;Barbara Lamb

  • Regulation of alternative polyadenylation by genomic imprinting

    Andrew J. Wood;Reiner Schulz;Kathryn Woodfine;Katarzyna Koltowska

  • DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

    Natasha Zamudio;Natasha Zamudio;Joan Barau;Joan Barau;Aurélie Teissandier;Marius Walter;Marius Walter

Frequent Co-Authors

Timothy H. Bestor
Timothy H. Bestor Columbia University
Rebecca J. Oakey
Rebecca J. Oakey King's College London
Gavin Kelsey
Gavin Kelsey Babraham Institute
Alexei A. Aravin
Alexei A. Aravin California Institute of Technology
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Steven E. Jacobsen
Steven E. Jacobsen University of California, Los Angeles
Yann Herault
Yann Herault Institute of Genetics and Molecular and Cellular Biology
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Jacquetta M. Trasler
Jacquetta M. Trasler McGill University Health Centre
Anne C. Ferguson-Smith
Anne C. Ferguson-Smith University of Cambridge

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