Alejandro V. Villarino

Best Publications

• Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

  Chih-Hao Chang;Jonathan D. Curtis;Leonard B. Maggi;Brandon Faubert

  2323
  Citations

• The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention*

  John J. O'Shea;Daniella M. Schwartz;Alejandro V. Villarino;Massimo Gadina

  1618
  Citations

• JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.

  Daniella M Schwartz;Yuka Kanno;Alejandro Villarino;Michael Ward

  1219
  Citations

• Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.

  Jason S Stumhofer;Arian Laurence;Emma H Wilson;Elaine Huang

  1201
  Citations

• Mechanisms and consequences of Jak–STAT signaling in the immune system

  Alejandro V Villarino;Yuka Kanno;John J O'Shea

  1168
  Citations

• Role of T-bet in Commitment of TH1 Cells Before IL-12-Dependent Selection

  Alan C. Mullen;Frances A. High;Anne S. Hutchins;Hubert W. Lee

  1167
  Citations

• An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

  Scott W. Canna;Adriana Almeida de Jesus;Sushanth Gouni;Stephen R. Brooks

  779
  Citations

• Mechanisms of Jak/STAT Signaling in Immunity and Disease

  Alejandro V. Villarino;Yuka Kanno;John R. Ferdinand;John J. O’Shea

  622
  Citations

• The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection

  Alejandro Villarino;Linda Hibbert;Linda Lieberman;Emma Wilson

  610
  Citations

• Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.

  Jonathan L. Linehan;Oliver J. Harrison;Seong Ji Han;Allyson L. Byrd;Allyson L. Byrd

  443
  Citations

• JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

  Unknown

  434
  Citations

• The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

  David Artis;Alejandro Villarino;Michael Silverman;Weimian He

  327
  Citations

• Understanding the Pro- and Anti-Inflammatory Properties of IL-27

  Alejandro V. Villarino;Elaine Huang;Christopher A. Hunter

  305
  Citations

• Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

  Jens Lohr;Birgit Knoechel;Jing Jing Wang;Alejandro V. Villarino

  299
  Citations

• IL-27 Limits IL-2 Production during Th1 Differentiation

  Alejandro V. Villarino;Jason S. Stumhofer;Christiaan J. M. Saris;Robert A. Kastelein

  286
  Citations

• T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

  Yelena Bronevetsky;Alejandro V. Villarino;Christopher J. Eisley;Rebecca Barbeau

  228
  Citations

• Positive and Negative Regulation of the IL-27 Receptor during Lymphoid Cell Activation

  Alejandro V. Villarino;Joseph Larkin;Christiaan J. M. Saris;Andrew J. Caton

  203
  Citations

• Distinct requirements for T-bet in gut innate lymphoid cells.

  Giuseppe Sciumé;Kiyoshi Hirahara;Hayato Takahashi;Arian Laurence

  185
  Citations

• Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.

  Kiyoshi Hirahara;Kiyoshi Hirahara;Atsushi Onodera;Alejandro V. Villarino;Michael Bonelli

  165
  Citations

• Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

  Alejandro V. Villarino;Cristina M. Tato;Jason S. Stumhofer;Zhengju Yao

  160
  Citations