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Molecular Biology

D-Index
44
Citations
8344
World Ranking
2920
National Ranking
1392

Overview

Elizabeth J. Taparowsky is affiliated with Purdue University West Lafayette in the United States. Their research primarily spans the fields of immunology and microbiology, with additional work in medicine. Within these areas, their subfields of study include immunology, surgery, and epidemiology.

Their research focuses on several key topics related to immune system function and regulation. These include immune cell function and interaction, immunotherapy and immune responses, IL-33, ST2, and innate lymphoid cell pathways, eosinophilic esophagitis, cytomegalovirus and herpesvirus research, and T-cell and B-cell immunology.

Taparowsky has contributed to scientific literature with a number of recent publications. Among these are:

  • "BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection," 2021, published in Nature Immunology
  • "BATF promotes group 2 innate lymphoid cell-mediated lung tissue protection during acute respiratory virus infection," 2022, published in Science Immunology
  • "Group 3 innate lymphoid cells require BATF to regulate gut homeostasis in mice," 2022, published in The Journal of Experimental Medicine
  • "BATF is Required for Treg Homeostasis and Stability to Prevent Autoimmune Pathology," 2023, published in Advanced Science

Their frequent co-authors include Xiaopeng Wu, Moujtaba Y. Kasmani, Robert Burns, Weiguo Cui, and Shikan Zheng. Taparowsky's work is distributed across several scientific venues, notably:

  • Nature Immunology
  • Science Immunology
  • The Journal of Experimental Medicine
  • Advanced Science

Taparowsky's publications highlight a focus on the regulation of immune cells such as T cells and innate lymphoid cells, as well as mechanisms underlying immune stability, autoimmune pathology, and viral infection responses. Their interdisciplinary approach integrates molecular immunology with insights relevant to clinical immunotherapy and disease mechanisms.

Best Publications

  • Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

    Elizabeth Taparowsky;Yolande Suard;Ottavio Fasano;Kenji Shimizu

  • Structure and activation of the human N-ras gene

    Elizabeth Taparowsky;Kenji Shimizu;Mitchell Goldfarb;Michael Wigler

  • Structure of the Ki- ras gene of the human lung carcinoma cell line Calu-1

    Kenji Shimizu;Kenji Shimizu;Daniel Birnbaum;Mary Ann Ruley;Ottavio Fasano

  • Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

    Ottavio Fasano;Thomas Aldrich;Fuyuhiko Tamanoi;Elizabeth Taparowsky

  • A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis

    Michelle Olive;Dmitry Krylov;Deborah R. Echlin;Kevin Gardner

  • Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1.

    T. B. Vaidya;Simon Rhodes;E. J. Taparowsky;S. F. Konieczny

  • OX40 signaling favors the induction of TH9 cells and airway inflammation

    Xiang Xiao;Savithri Balasubramanian;Wentao Liu;Xiufeng Chu

  • Batf coordinates multiple aspects of B and T cell function required for normal antibody responses

    Briana C. Betz;Kimberly L. Jordan-Williams;Chuanwu Wang;Seung Goo Kang

  • Th9 cell development requires a BATF-regulated transcriptional network

    Rukhsana Jabeen;Ritobrata Goswami;Olufolakemi Awe;Aishwarya Kulkarni

  • Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation

    Shuyu Yao;Bruno Fernando d. Buzo;Duy Pham;Li Jiang

  • Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut.

    Myung H. Kim;Elizabeth J. Taparowsky;Chang H. Kim

  • Deciphering B-ZIP transcription factor interactions in vitro and in vivo.

    Charles Vinson;Asha Acharya;Elizabeth J. Taparowsky

  • Mist1-KrasG12D Knock-In Mice Develop Mixed Differentiation Metastatic Exocrine Pancreatic Carcinoma and Hepatocellular Carcinoma

    David A. Tuveson;Liqin Zhu;Aarthi Gopinathan;Nicholas A. Willis

  • B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family.

    M. J. Dorsey;Hyi-Jeong Tae;K. G. Sollenberger;N. T. Mascarenhas

  • Altered phosphatidylcholine metabolism in C3H10T1/2 cells transfected with the Harvey-ras oncogene.

    D Teegarden;E J Taparowsky;C Kent

  • Cross-Species Annotation of Basic Leucine Zipper Factor Interactions: Insight into the Evolution of Closed Interaction Networks

    Christopher D. Deppmann;Rebecca S. Alvania;Elizabeth J. Taparowsky

  • Inhibition of myogenic differentiation by the H-ras oncogene is associated with the down regulation of the MyoD1 gene.

    S F Konieczny;B L Drobes;S L Menke;E J Taparowsky

  • B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos.

    Deborah R. Echlin;Hyi Jeong Tae;Natalia Mitin;Elizabeth J. Taparowsky

  • Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana : a comparison to Homo sapiens B-ZIP motifs

    Christopher D. Deppmann;Asha Acharya;Vikas Rishi;Barry Wobbes

  • Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization

    Han Liu;Xuehong Deng;Y John Shyu;Jian Jian Li

Frequent Co-Authors

Stephen F. Konieczny
Stephen F. Konieczny Purdue University West Lafayette
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
Mitchell Goldfarb
Mitchell Goldfarb Hunter College
Mark H. Kaplan
Mark H. Kaplan Indiana University
Chang H. Kim
Chang H. Kim University of Michigan–Ann Arbor
Charles Vinson
Charles Vinson National Institutes of Health
Xian Chang Li
Xian Chang Li Cornell University
Michael S. Kinch
Michael S. Kinch Washington University in St. Louis
Jian Jian Li
Jian Jian Li University of California, Davis
Indrajit Nanda
Indrajit Nanda University of Würzburg

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