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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
18111
World Ranking
12948
National Ranking
5515

Research.com Recognitions

  • 2002 - Hellman Fellow

Overview

Walther Mothes is affiliated with Yale University in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a significant emphasis on Infectious Diseases, Virology, Molecular Biology, Immunology, and Radiology, Nuclear Medicine and Imaging.

Their work covers various main topics including:

  • SARS-CoV-2 and COVID-19 Research
  • HIV Research and Treatment
  • COVID-19 Clinical Research Studies
  • Monoclonal and Polyclonal Antibodies Research
  • HIV/AIDS drug development and treatment
  • Viral gastroenteritis research and epidemiology
  • Bacteriophages and microbial interactions

Mothes has contributed to multiple recent papers, including:

  • Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles, 2020, Cell Host & Microbe
  • Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy, 2021, Immunity
  • A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses, 2021, Cell Host & Microbe
  • Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern, 2021, Cell Reports
  • A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection, 2022, Cell Reports

They frequently publish in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Nature
  • SSRN Electronic Journal
  • Biophysical Journal

Mothes collaborates regularly with several other researchers, including:

  • Pradeep D. Uchil
  • Andrés Finzi
  • Priti Kumar
  • Shilei Ding
  • Irfan Ullah

In 2002, Walther Mothes was awarded the Hellman Fellow recognition.

Best Publications

  • Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.

    Emmanuel J. H. J. Wiertz;Domenico Tortorella;Matthew Bogyo;Joyce Yu

  • Structure and immune recognition of trimeric pre-fusion HIV-1 Env

    Marie Pancera;Tongqing Zhou;Aliaksandr Druz;Ivelin S. Georgiev

  • TRIM5 is an innate immune sensor for the retrovirus capsid lattice

    Thomas Pertel;Stéphane Hausmann;Damien Morger;Sara Züger

  • Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection

    Jan Münch;Elke Rücker;Ludger Ständker;Knut Adermann

  • Secreted cathepsin L generates endostatin from collagen XVIII

    Ute Felbor;Lars Dreier;Rebecca A.R. Bryant;Hidde L. Ploegh

  • Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithms

    Fang Huang;Tobias M P Hartwich;Tobias M P Hartwich;Tobias M P Hartwich;Felix E Rivera-Molina;Yu Lin

  • Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

    James B. Munro;Jason Gorman;Xiaochu Ma;Zhou Zhou

  • Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission.

    Nathan M. Sherer;Maik J. Lehmann;Maik J. Lehmann;Luisa F. Jimenez-Soto;Luisa F. Jimenez-Soto;Christina Horensavitz

  • Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells.

    Maik J. Lehmann;Nathan M. Sherer;Carolyn B. Marks;Marc Pypaert

  • Visualization of retroviral replication in living cells reveals budding into multivesicular bodies.

    Nathan M. Sherer;Maik J. Lehmann;Luisa F. Jimenez-Soto;Alyssa Ingmundson

  • Signal Sequence Recognition in Posttranslational Protein Transport across the Yeast ER Membrane

    Kathrin Plath;Walther Mothes;Barrie M Wilkinson;Colin J Stirling

  • Protein translocation: tunnel vision.

    Kent E.S Matlack;Walther Mothes;Tom A Rapoport

  • Neuronal loss and brain atrophy in mice lacking cathepsins B and L.

    Ute Felbor;Benedikt Kessler;Walther Mothes;Hans H. Goebel

  • Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

    Young Do Kwon;Marie Pancera;Priyamvada Acharya;Ivelin S. Georgiev

  • Virus Cell-to-Cell Transmission

    Walther Mothes;Nathan M. Sherer;Jing Jin;Peng Zhong

  • Retroviral Entry Mediated by Receptor Priming and Low pH Triggering of an Envelope Glycoprotein

    Walther Mothes;Adrienne L. Boerger;Shakti Narayan;James M. Cunningham;James M. Cunningham

  • Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

    Rui Kong;Kai Xu;Tongqing Zhou;Priyamvada Acharya

  • Human TRIM Gene Expression in Response to Interferons

    Laetitia Carthagena;Anna Bergamaschi;Joseph M. Luna;Annie David

  • Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides.

    Robin Chan;Pradeep D. Uchil;Jing Jin;Guanghou Shui

  • The Sec61p Complex Mediates the Integration of a Membrane Protein by Allowing Lipid Partitioning of the Transmembrane Domain

    Sven U Heinrich;Walther Mothes;Josef Brunner;Tom A Rapoport

Frequent Co-Authors

Scott C. Blanchard
Scott C. Blanchard St. Jude Children's Research Hospital
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Andrés Finzi
Andrés Finzi University of Montreal
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Amos B. Smith
Amos B. Smith University of Pennsylvania
Jeremy Luban
Jeremy Luban University of Massachusetts Chan Medical School
Tongqing Zhou
Tongqing Zhou National Institutes of Health
Tom A. Rapoport
Tom A. Rapoport Harvard University
James Arthos
James Arthos National Institute of Allergy and Infectious Diseases
Pamela J. Bjorkman
Pamela J. Bjorkman California Institute of Technology

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