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Immunology

D-Index
61
Citations
19850
World Ranking
3195
National Ranking
1497

Overview

James Arthos is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research primarily spans immunology and microbiology, with a significant focus on medicine. Arthos's work encompasses several subfields including immunology, virology, infectious diseases, epidemiology, and molecular biology.

The scientist's research topics include:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology
  • HIV/AIDS Drug Development and Treatment
  • COVID-19 Clinical Research Studies
  • Monoclonal and Polyclonal Antibodies Research

Recent scientific papers by James Arthos include the following publications:

  • "SARS-CoV-2 genomic analyses in cancer patients reveal elevated intrahost genetic diversity," 2021, Virus Evolution
  • "Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands," 2020, Journal of Virology
  • "Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes," 2020, PLoS Pathogens
  • "Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates," 2021, iScience
  • "HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions," 2020, JCI Insight

James Arthos frequently collaborates with other researchers in the field. Notable co-authors with repeated collaborations include Claudia Cicala, Lívia R. Góes, Marcelo A. Soares, Danlan Wei, and Elena Martinelli.

The most common venues for Arthos's publications reflect their focus on virology and immunology and include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • PLoS Pathogens
  • JCI Insight
  • Nature Communications

Best Publications

  • CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

    Alexandra Trkola;Tatjana Dragic;James Arthos;James M. Binley

  • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

    Susan Moir;Jason Ho;Angela Malaspina;Wei-wei Wang

  • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

    Peter D. Kwong;Peter D. Kwong;Michael L. Doyle;Michael L. Doyle;David J. Casper;Claudia Cicala

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Structural definition of a conserved neutralization epitope on HIV-1 gp120.

    Tongqing Zhou;Ling Xu;Barna Dey;Ann J. Hessell

  • HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

    James Arthos;Claudia Cicala;Elena Martinelli;Elena Martinelli;Katilyn Macleod

  • Crystal structure of an HIV-binding recombinant fragment of human CD4.

    Seong Eon Ryu;Peter D. Kwong;Alemseged Truneh;Terence G. Porter

  • A soluble form of CD4 (T4) protein inhibits AIDS virus infection.

    K C Deen;J S McDougal;R Inacker;G Folena-Wasserman

  • Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

    James B. Munro;Jason Gorman;Xiaochu Ma;Zhou Zhou

  • Identification of the Residues in Human CD4 Critical for the Binding of HIV

    J Arthos;K C Deen;M A Chaikin;J A Fornwald

  • Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

    Drew Weissman;Ronald L. Rabin;James Arthos;Andrea Rubbert

  • Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

    Craig B. Davis;Ivan Dikic;Derya Unutmaz;C. Mark Hill

  • Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

    Young Do Kwon;Marie Pancera;Priyamvada Acharya;Ivelin S. Georgiev

  • Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.

    Lei Chen;Young Do Kwon;Tongqing Zhou;Xueling Wu

  • The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

    Claudia Cicala;Elena Martinelli;Jonathan P. McNally;Diana J. Goode

  • Simian immunodeficiency virus DNA vaccine trial in macaques.

    Shan Lu;James Arthos;David C. Montefiori;Yasuhiro Yasutomi

  • HIV gp120 receptors on human dendritic cells.

    Stuart G. Turville;Stuart G. Turville;Jim Arthos;Jim Arthos;Kelli Mac Donald;Kelli Mac Donald;Garry Lynch;Garry Lynch

  • HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in plasmacytoid dendritic cells

    Elena Martinelli;Claudia Cicala;Donald Van Ryk;Diana J. Goode

  • Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy

    Siddappa N. Byrareddy;James Arthos;Claudia Cicala;Francois Villinger

  • CC-chemokines enhance the replication of T-tropic strains of HIV-1 in CD4(+) T cells: role of signal transduction.

    Audrey Kinter;Andrew Catanzaro;JoAn Monaco;Margaret Ruiz

  • Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime–protein boost HIV-1 vaccine in healthy human volunteers

    Shixia Wang;Jeffrey S. Kennedy;Kim West;David C. Montefiori

Frequent Co-Authors

Anthony S. Fauci
Anthony S. Fauci Georgetown University
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Richard Axel
Richard Axel Columbia University
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Paul J. Maddon
Paul J. Maddon Columbia University
Tongqing Zhou
Tongqing Zhou National Institutes of Health
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Dimiter S. Dimitrov
Dimiter S. Dimitrov University of Pittsburgh
Gary J. Nabel
Gary J. Nabel ModeX Therapeutics

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