World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
78
Citations
19663
World Ranking
1774
National Ranking
875

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors
  • 1988 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Carl R. Alving is affiliated with the Walter Reed Army Institute of Research in the United States. The core focus of their research lies in immunology, molecular biology, and medicine, with specific attention to immunotherapy and immune responses. Their work spans several related fields, including epidemiology, virology, infectious diseases, biochemistry, genetics, and molecular biology.

Their scientific contributions include published research in multiple well-known venues. Frequent publication sites include:

  • Vaccines
  • Pharmaceutics
  • Open Forum Infectious Diseases
  • Expert Review of Vaccines
  • PLoS Pathogens

Among recent papers authored or co-authored by Carl R. Alving are:

  • "Army Liposome Formulation (ALF) family of vaccine adjuvants," 2020, Expert Review of Vaccines
  • "Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge," 2020, PLoS Pathogens
  • "Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques," 2021, npj Vaccines
  • "Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria," 2021, Vaccines
  • "Similarities and differences of chemical compositions and physical and functional properties of adjuvant system 01 and army liposome formulation with QS21," 2023, Frontiers in Immunology

Their research topics cover several areas including:

  • Immunotherapy and Immune Responses
  • Influenza Virus Research Studies
  • HIV Research and Treatment
  • RNA Interference and Gene Delivery
  • Vaccines and Immunoinformatics Approaches
  • Viral Gastroenteritis Research and Epidemiology
  • Malaria Research and Control

Carl R. Alving often collaborates with a range of co-authors. Some frequent collaborators include:

  • Gary R. Matyas
  • Mangala Rao
  • Zoltán Beck
  • Kristina K. Peachman
  • Clara J. Sei

The scientist has been recognized by professional organizations with awards such as:

  • Fellow, National Academy of Inventors, 2016
  • Fellow of the American Association for the Advancement of Science (AAAS), 1988

Best Publications

  • Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil®): possible role in hypersensitivity reactions

    Asher Chanan-Khan;J. Szebeni;S. Savay;L. Liebes

  • Liposomes as carriers of antigens and adjuvants.

    Carl R. Alving

  • Transcutaneous immunization: a human vaccine delivery strategy using a patch.

    Gregory M. Glenn;David N. Taylor;Xiuru Li;Sarah Frankel

  • Skin immunization made possible by cholera toxin

    Gregory M. Glenn;Mangala Rao;Gary R. Matyas;Carl R. Alving

  • Complement Activation by Cremophor EL as a Possible Contributor to Hypersensitivity to Paclitaxel: an In Vitro Study

    Janos Szebeni;Franco M. Muggia;Franco M. Muggia;Carl R. Alving

  • Therapy of leishmaniasis: Superior efficacies of liposome-encapsulated drugs

    Carl R. Alving;Edgar A. Steck;Willie L. Chapman;Virginia B. Waits

  • Liposome carriers in chemotherapy of leishmaniasis

    Edgar A. Steck;Carl R. Alving

  • Liposomal malaria vaccine in humans: a safe and potent adjuvant strategy

    Louis F. Fries;Daniel M. Gordon;Roberta L. Richards;James E. Egan

  • Adjuvants for human vaccines

    Carl R Alving;Kristina K Peachman;Mangala Rao;Steven G Reed

  • F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins.

    Milan Basta;Fredric Van Goor;Stefano Luccioli;Eric M. Billings

  • Complement-dependent damage to liposomes prepared from pure lipids and Forssman hapten.

    Stephen C. Kinsky;James A. Haxby;David A. Zopf;Carl R. Alving

  • Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies.

    J. Szebeni;L. Baranyi;S. Savay;J. Milosevits

  • Lipopolysaccharide, lipid A, and liposomes containing lipid A as immunologic adjuvants

    Carl R. Alving

  • Hemodynamic Changes Induced by Liposomes and Liposome-Encapsulated Hemoglobin in Pigs A Model for Pseudoallergic Cardiopulmonary Reactions to Liposomes: Role of Complement and Inhibition by Soluble CR1 and Anti-C5a Antibody

    Janos Szebeni;John L. Fontana;Nabila M. Wassef;Paul D. Mongan

  • Transcutaneous Immunization with Bacterial ADP-Ribosylating Exotoxins, Subunits, and Unrelated Adjuvants

    Tanya Scharton-Kersten;Jian-mei Yu;Russell Vassell;Derek O'Hagan

  • Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge.

    Gregory M. Glenn;Tanya Scharton-Kersten;Russell Vassell;Corey P. Mallett

  • Animal Models of Complement-Mediated Hypersensitivity Reactions to Liposomes and Other Lipid-Based Nanoparticles

    János Szebeni;Carl R. Alving;László Rosivall;Rolf Bünger

  • Safety and Immunogenicity of a Prototype Enterotoxigenic Escherichia coli Vaccine Administered Transcutaneously

    Fernando Güereña-Burgueño;Eric R. Hall;David N. Taylor;Frederick J. Cassels

  • Liposome-induced pulmonary hypertension: properties and mechanism of a complement-mediated pseudoallergic reaction

    Janos Szebeni;Lajos Baranyi;Sandor Savay;Mihaly Bodo

  • Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants.

    Gregory M. Glenn;Tanya Scharton-Kersten;Russell Vassell;Gary R. Matyas

  • Liposomes as carriers of peptide antigens: induction of antibodies and cytotoxic T lymphocytes to conjugated and unconjugated peptides.

    C. R. Alving;V. Koulchin;G. M. Glenn;Mangala Rao

Frequent Co-Authors

Janos Szebeni
Janos Szebeni Semmelweis University
Andrew S. Janoff
Andrew S. Janoff Princeton University
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Arthur E. Jacobson
Arthur E. Jacobson National Institutes of Health
Victoria R. Polonis
Victoria R. Polonis Walter Reed Army Institute of Research
Nelson L. Michael
Nelson L. Michael Walter Reed Army Institute of Research
Venigalla B. Rao
Venigalla B. Rao Catholic University of America
Jerome H. Kim
Jerome H. Kim Walter Reed Army Institute of Research
Joel Moss
Joel Moss National Institutes of Health
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health

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