2026 Jeffrey S. Flier: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Medicine	152	1062	976	610	547	348	112606

Research.com Recognitions

2003 - Member of the National Academy of Medicine (NAM)
2001 - Fellow of the American Academy of Arts and Sciences
1999 - Fellow of the American Association for the Advancement of Science (AAAS)
Member of the Association of American Physicians
Member of the Association of American Physicians

Overview

Jeffrey S. Flier is affiliated with Harvard University in the United States. Their primary field of study is Medicine, with a focus on several subfields including Molecular Biology, Physiology, Endocrinology, Diabetes and Metabolism, Endocrine and Autonomic Systems, and Reproductive Medicine.

The scientist's research topics cover a range of areas related to metabolism and disease, including:

Regulation of Appetite and Obesity
Adipose Tissue and Metabolism
Metabolism, Diabetes, and Cancer
Diet and Metabolism Studies
Diabetes Treatment and Management
Science, Research, and Medicine
Cell Image Analysis Techniques

Their recent notable publications include:

"Insulin: A pacesetter for the shape of modern biomedical science and the Nobel Prize" (2021), published in Molecular Metabolism
"Moderating "the great debate": The carbohydrate-insulin vs. the energy balance models of obesity" (2023), published in Cell Metabolism
"Might β3-adrenergic receptor agonists be useful in disorders of glucose homeostasis?" (2020), published in Journal of Clinical Investigation
"Leptin physiology and pathophysiology: knowns and unknowns 30 years after its discovery" (2024), published in Journal of Clinical Investigation

Jeffrey S. Flier has collaborated frequently with several co-authors, including Igor R. Efimov, Anna I. Krylov, Luana S. Maroja, Julia Schaletzky, and Jay Tanzman, each contributing to multiple publications.

The main venues for the scientist's work include:

Perspectives in Biology and Medicine
Journal of Clinical Investigation
Molecular Metabolism
Cell Metabolism
Frontiers in Research Metrics and Analytics

Their career has been recognized with several professional memberships and fellowships:

Member of the National Academy of Medicine (NAM), since 2003
Fellow of the American Academy of Arts and Sciences, since 2001
Fellow of the American Association for the Advancement of Science (AAAS), since 1999
Member of the Association of American Physicians

Best Publications

Adipose Tissue as an Endocrine Organ

Erin E. Kershaw;Jeffrey S. Flier

6955
Citations
Obesity and insulin resistance

Barbara B. Kahn;Jeffrey S. Flier

4383
Citations
TLR4 links innate immunity and fatty acid–induced insulin resistance

Hang Shi;Maia V. Kokoeva;Karen Inouye;Iphigenia Tzameli

4207
Citations
Role of leptin in the neuroendocrine response to fasting

Rexford S. Ahima;Daniel Prabakaran;Christos Mantzoros;Daqing Qu

4129
Citations
Obesity and the Regulation of Energy Balance

Bruce M. Spiegelman;Jeffrey S. Flier

3162
Citations
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome

Hiroaki Masuzaki;Janice Paterson;Hiroshi Shinyama;Nicholas M. Morton

2300
Citations
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

Robert C. Frederich;Andreas Hamann;Stephen Anderson;Bettina Löllmann

2130
Citations
Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

Michael K. Badman;Pavlos Pissios;Adam R. Kennedy;George Koukos

1685
Citations
Adipogenesis and obesity: rounding out the big picture.

Bruce M Spiegelman;Jeffrey S Flier

1664
Citations
Obesity Wars: Molecular Progress Confronts an Expanding Epidemic

Jeffrey S Flier

1637
Citations
The organization, promoter analysis, and expression of the human PPARgamma gene.

Lluis Fajas;Didier Auboeuf;Eric Raspé;Kristina Schoonjans

1624
Citations
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

ffolliott M. Fisher;Sandra Kleiner;Nicholas Douris;Elliott C. Fox

1593
Citations
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

Bradford B. Lowell;Vedrana S-Susulic;Andreas Hamann;Joel A. Lawitts

1590
Citations
Mice lacking melanin-concentrating hormone are hypophagic and lean

Masako Shimada;Nicholas A. Tritos;Bradford B. Lowell;Jeffrey S. Flier

1418
Citations
The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man.

C R Kahn;J S Flier;R S Bar;J A Archer

1387
Citations
Distributions of leptin receptor mRNA isoforms in the rat brain.

Joel K. Elmquist;Christian Bjørbæk;Rexford S. Ahima;Jeffrey S. Flier

1342
Citations
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Karim El-Haschimi;Dominique D. Pierroz;Stanley M. Hileman;Christian Bjørbæk

1278
Citations
Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor

Christian Bjørbæk;Shigeo Uotani;Barbara da Silva;Jeffrey S. Flier

1260
Citations
Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

Christian Bjørbæk;Joel K Elmquist;J.Daniel Frantz;Steven E Shoelson

1256
Citations
Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes

Jeffrey S. Flier;Jeffrey S. Flier;Michael M. Mueckler;Michael M. Mueckler;Patricia Usher;Harvey F. Lodish

1134
Citations

Frequent Co-Authors

Eleftheria Maratos-Flier Beth Israel Deaconess Medical Center

David E. Moller Eli Lilly (United States)

Bradford B. Lowell Beth Israel Deaconess Medical Center

Bruce M. Spiegelman Harvard University

Christos S. Mantzoros Beth Israel Deaconess Medical Center

Joel K. Elmquist The University of Texas Southwestern Medical Center

Rexford S. Ahima Johns Hopkins University

Barbara B. Kahn Beth Israel Deaconess Medical Center

Martin C. Carey Brigham and Women's Hospital

External Links

Personal website of Jeffrey S. Flier

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