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Biology and Biochemistry

D-Index
58
Citations
19933
World Ranking
12927
National Ranking
266

Overview

Miguel A. Peinado is affiliated with the Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol in Spain. Their research primarily spans the domain of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology and Genetics.

Their work covers several specialized subfields including Cancer Research, Pulmonary and Respiratory Medicine, and Pathology and Forensic Medicine. The main topics investigated are Epigenetics and DNA Methylation, Histone Deacetylase Inhibitors Research, and Cancer Genomics and Diagnostics. Additionally, they have contributed to studies on Ferroptosis and cancer prognosis, Genetic factors in colorectal cancer, Adipose Tissue and Metabolism, and Muscle Physiology and Disorders.

Recent papers authored or co-authored by Miguel A. Peinado include:

  • DNA Methylation Events in Transcription Factors and Gene Expression Changes in Colon Cancer, 2020, published in Epigenomics
  • HDAC11 is a novel regulator of fatty acid oxidative metabolism in skeletal muscle, 2020, published in FEBS Journal
  • Loss of HDAC11 accelerates skeletal muscle regeneration in mice, 2020, published in FEBS Journal
  • Mycobacterium manresensis induces trained immunity in vitro, 2023, published in iScience
  • CpG methylation frequency of TET2, GRIA2, and CDKN2A genes in the North Atlantic fin whale varies with age and between populations, 2021, published in Marine Mammal Science

Frequent co-authors in their publications include:

  • Berta Martín
  • Anna Díez-Villanueva
  • Víctor Moreno
  • Ferran Moratalla-Navarro
  • Erica Hurtado

The primary publication venues for their research contributions are:

  • FEBS Journal
  • Epigenomics
  • iScience
  • Marine Mammal Science
  • Epigenetics

Best Publications

  • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

    Yurij Ionov;Miguel A. Peinado;Sergei Malkhosyan;Darryl Shibata

  • Insights into social insects from the genome of the honeybee Apis mellifera

    George M. Weinstock;Gene E. Robinson;Richard A. Gibbs;Kim C. Worley

  • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

    Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour

  • Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

    Manel Esteller;Andrew Sparks;Minoru Toyota;Montserrat Sanchez-Cespedes

  • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

    Manel Esteller;Minoru Toyota;Montserrat Sanchez-Cespedes;Gabriel Capella

  • Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.

    Manel Esteller;Silvia Tortola;Minoru Toyota;Gabriel Capella

  • Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation.

    Shibata D;Peinado Ma;Ionov Y;Malkhosyan S

  • DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

    Manel Esteller;Mario F. Fraga;Mingzhou Guo;Jesus Garcia-Foncillas

  • regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests

    Bernat Gel;Anna Díez-Villanueva;Eduard Serra;Marcus Buschbeck

  • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band

    Jordi Frigola;Jenny Song;Clare Stirzaker;Rebecca A Hinshelwood

  • Promoter Hypermethylation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase Is Associated with the Presence of G:C to A:T Transition Mutations in p53 in Human Colorectal Tumorigenesis

    Manel Esteller;Rosa Ana Risques;Minoru Toyota;Gabriel Capella

  • Chromosomal Instability Correlates with Genome-wide DNA Demethylation in Human Primary Colorectal Cancers

    Jairo Rodriguez;Jordi Frigola;Elisenda Vendrell;Rosa Ana Risques

  • Functional CpG Methylation System in a Social Insect

    Ying Wang;Mireia Jorda;Peter L. Jones;Rjrszard Maleszka

  • K-ras and p16 Aberrations Confer Poor Prognosis in Human Colorectal Cancer

    M. Esteller;S. González;R. A. Risques;E. Marcuello

  • p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas.

    Luis Hernandez;Thierry Fest;Maite Cazorla;Julie Teruya-Feldstein

  • Germ-Line Variants in Methyl-Group Metabolism Genes and Susceptibility to DNA Methylation in Normal Tissues and Human Primary Tumors

    Maria F. Paz;Sonia Avila;Mario F. Fraga;Marina Pollan

  • Comparative analysis of mutations in the p53 and K‐ras genes in pancreatic cancer

    Georgina Berrozpe;James Schaeffer;Miguel Angel Peinado;Francisco X. Real

  • Epigenetics of host-pathogen interactions: the road ahead and the road behind.

    Elena Gómez-Díaz;Mireia Jordà;Miguel Angel Peinado;Ana Rivero

  • A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA.

    Federica Gemignani;Federica Gemignani;Victor Moreno;Stefano Landi;Stefano Landi;Norman Moullan

  • Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer.

    Manel Esteller;Mingzhou Guo;Victor Moreno;Miquel Angel Peinado

Frequent Co-Authors

Gabriel Capellá
Gabriel Capellá Institut d'Investigació Biomédica de Bellvitge
Victor Moreno
Victor Moreno University of Barcelona
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Manuel Perucho
Manuel Perucho Discovery Institute
James G. Herman
James G. Herman University of Pittsburgh
Stephen B. Baylin
Stephen B. Baylin Johns Hopkins University
Denis F. Hochstrasser
Denis F. Hochstrasser University of Geneva
Michael McClelland
Michael McClelland University of California, Irvine
Susan J. Clark
Susan J. Clark Garvan Institute of Medical Research
Mario F. Fraga
Mario F. Fraga University of Oviedo

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