What is she best known for?
The fields of study she is best known for:
Linda J. Van Eldik mainly investigates Cell biology, Astrocyte, Immunology, Neuroglia and Microglia.
The Cell biology study combines topics in areas such as Secretion, Nitric oxide synthase, Neurodegeneration and P3 peptide.
She focuses mostly in the field of Neurodegeneration, narrowing it down to matters related to Presenilin and, in some cases, Senile plaques.
Her work deals with themes such as Inflammation, Occipital lobe, Biochemistry and Cerebellum, which intersect with Astrocyte.
Linda J. Van Eldik has researched Neuroglia in several fields, including Neurotrophin and MAPK/ERK pathway, p38 mitogen-activated protein kinases.
Her studies in Microglia integrate themes in fields like Proinflammatory cytokine and Receptor.
Her most cited work include:
- Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. (1606 citations)
- The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain. (325 citations)
- Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric-oxide synthase by 15-deoxy-Δ12,14-prostaglandin J2 (315 citations)
What are the main themes of her work throughout her whole career to date?
Cell biology, Biochemistry, Neuroinflammation, Microglia and Neuroscience are her primary areas of study.
Her Cell biology research is multidisciplinary, incorporating elements of Nitric oxide synthase and Astrocyte.
Her research in Neuroinflammation focuses on subjects like Proinflammatory cytokine, which are connected to Downregulation and upregulation, Neurodegeneration, Central nervous system and Cancer research.
Her Microglia study combines topics from a wide range of disciplines, such as Interleukin, Cytokine, Neuroglia, Prostaglandin and Amyloid.
Her research in Amyloid intersects with topics in P3 peptide and Amyloid precursor protein.
Her Neuroscience study integrates concerns from other disciplines, such as Alzheimer's disease and Drug discovery.
She most often published in these fields:
- Cell biology (33.67%)
- Biochemistry (23.47%)
- Neuroinflammation (20.41%)
What were the highlights of her more recent work (between 2007-2016)?
- Proinflammatory cytokine (16.33%)
- Immunology (14.29%)
- Cell biology (33.67%)
In recent papers she was focusing on the following fields of study:
Linda J. Van Eldik focuses on Proinflammatory cytokine, Immunology, Cell biology, Cytokine and Chemokine.
Her Proinflammatory cytokine research includes elements of Neuroinflammation, MAPK/ERK pathway and Drug discovery.
Her Immunology study deals with Central nervous system intersecting with Drug target and Multiple sclerosis.
Her study in p38 mitogen-activated protein kinases and Protein kinase A is carried out as part of her studies in Cell biology.
Linda J. Van Eldik regularly ties together related areas like Microglia in her Cytokine studies.
Her Inflammation research incorporates elements of Peripheral and Endocrinology.
Between 2007 and 2016, her most popular works were:
- Targeting protein kinases in central nervous system disorders (193 citations)
- Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury (152 citations)
- Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes (151 citations)
In her most recent research, the most cited papers focused on:
Her primary areas of study are Immunology, Proinflammatory cytokine, Chemokine, Cell biology and Microglia.
The various areas that she examines in her Immunology study include Drug target, Neuroscience, Central nervous system and Pharmacoinformatics.
Her research integrates issues of Cytokine, Downregulation and upregulation, CCL7 and MAPK/ERK pathway, p38 mitogen-activated protein kinases in her study of Proinflammatory cytokine.
Her Chemokine study combines topics in areas such as Cell culture, Phagocyte, Phagocytosis, Neuroglia and Apoptosis.
Her study ties her expertise on Macrophage together with the subject of Cell biology.
Her study in Microglia is interdisciplinary in nature, drawing from both Neuroinflammation and Neuroprotection.
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