2023 - Research.com Biology and Biochemistry in Italy Leader Award
His primary areas of investigation include Longevity, Genetics, Allele, Immunology and Endocrinology. His study with Longevity involves better knowledge in Gerontology. His studies deal with areas such as Genetic predisposition, Transition, Interleukin 6, Centenarian and Genotype as well as Allele.
Massimiliano Bonafè has researched Immunology in several fields, including Phenotype, Disease and Microvesicles. The various areas that Massimiliano Bonafè examines in his Endocrinology study include Drosophila melanogaster, Internal medicine, Cytokine and Yeast. His study in Immunosenescence is interdisciplinary in nature, drawing from both Network theory of aging, Innate immune system and Immunity.
Genetics, Internal medicine, Longevity, Cancer research and Immunology are his primary areas of study. His biological study spans a wide range of topics, including Endocrinology and Oncology. His work carried out in the field of Endocrinology brings together such families of science as Receptor and Cytokine.
His research on Longevity also deals with topics like
His primary areas of study are Cancer research, Cancer, Breast cancer, Internal medicine and Immunology. Massimiliano Bonafè interconnects Molecular biology, Urinary system and Pathology in the investigation of issues within Cancer. The study incorporates disciplines such as Immunohistochemistry, Cancer stem cell, Androgen receptor and ErbB Receptors in addition to Breast cancer.
His Internal medicine research is multidisciplinary, incorporating elements of Endocrinology, Gerontology and Oncology. Many of his studies on Immunology involve topics that are commonly interrelated, such as Mitochondrial DNA. Massimiliano Bonafè studies Immune system, focusing on Immunosenescence in particular.
His scientific interests lie mostly in Cancer research, Cancer, Immunology, Microvesicles and Breast cancer. Massimiliano Bonafè combines subjects such as Multicellular organism, High Throughput Assay and Anticancer drug with his study of Cancer research. His Cancer research is multidisciplinary, incorporating perspectives in Gerontology, Oncology and Pathology.
His work on Immunosenescence, Immune system and Tumor necrosis factor alpha as part of general Immunology study is frequently connected to Plasminogen activator inhibitor-1, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His study in Microvesicles is interdisciplinary in nature, drawing from both Phenotype, Metastasis, Mitochondrial DNA and Cell biology. His studies deal with areas such as Cancer cell and Cancer stem cell as well as Breast cancer.
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Inflamm‐aging: An Evolutionary Perspective on Immunosenescence
Claudio Franceschi;Massimiliano Bonafè;Silvana Valensin;Fabiola Olivieri.
Annals of the New York Academy of Sciences (2006)
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
Pasquale Sansone;Gianluca Storci;Simona Tavolari;Tiziana Guarnieri.
Journal of Clinical Investigation (2007)
Bone Marrow Cells Differentiate in Cardiac Cell Lineages After Infarction Independently of Cell Fusion
Jan Kajstura;Marcello Rota;Brian Whang;Stefano Cascapera.
Circulation Research (2004)
Human immunosenescence: The prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
Claudio Franceschi;Massimiliano Bonafè;Silvana Valensin.
Vaccine (2000)
Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans
Michelangela Barbieri;Massimiliano Bonafè;Claudio Franceschi;Giuseppe Paolisso.
American Journal of Physiology-endocrinology and Metabolism (2003)
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans
G. De Benedictis;G. Rose;G. Carrieri;M. De Luca.
The FASEB Journal (1999)
The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis
Qing Chang;Eirini Bournazou;Pasquale Sansone;Marjan Berishaj.
Neoplasia (2013)
The network and the remodeling theories of aging: historical background and new perspectives
C Franceschi;S Valensin;M Bonafè;G Paolisso.
Experimental Gerontology (2000)
Centenarians as a model for healthy aging
C. Franceschi;M. Bonafè.
Biochemical Society Transactions (2003)
A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity.
Massimiliano Bonafè;Fabiola Olivieri;Luca Cavallone;Simona Giovagnetti.
European Journal of Immunology (2001)
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