D-Index & Metrics Best Publications
Massimiliano Bonafè

Massimiliano Bonafè

Biology and Biochemistry
Italy
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 20,549 176 World Ranking 3680 National Ranking 74

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

His primary areas of investigation include Longevity, Genetics, Allele, Immunology and Endocrinology. His study with Longevity involves better knowledge in Gerontology. His studies deal with areas such as Genetic predisposition, Transition, Interleukin 6, Centenarian and Genotype as well as Allele.

Massimiliano Bonafè has researched Immunology in several fields, including Phenotype, Disease and Microvesicles. The various areas that Massimiliano Bonafè examines in his Endocrinology study include Drosophila melanogaster, Internal medicine, Cytokine and Yeast. His study in Immunosenescence is interdisciplinary in nature, drawing from both Network theory of aging, Innate immune system and Immunity.

His most cited work include:

  • Inflamm‐aging: An Evolutionary Perspective on Immunosenescence (2549 citations)
  • IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland (644 citations)
  • Bone Marrow Cells Differentiate in Cardiac Cell Lineages After Infarction Independently of Cell Fusion (454 citations)

What are the main themes of his work throughout his whole career to date?

Genetics, Internal medicine, Longevity, Cancer research and Immunology are his primary areas of study. His biological study spans a wide range of topics, including Endocrinology and Oncology. His work carried out in the field of Endocrinology brings together such families of science as Receptor and Cytokine.

His research on Longevity also deals with topics like

  • Gene which is related to area like Insulin-like growth factor,
  • Chromosomal region, which have a strong connection to Tyrosine hydroxylase. His Cancer research research incorporates elements of Tumor necrosis factor alpha, Cancer stem cell, Breast cancer and Metastasis. As part of his studies on Immunology, Massimiliano Bonafè often connects relevant areas like Disease.

He most often published in these fields:

  • Genetics (26.32%)
  • Internal medicine (26.32%)
  • Longevity (23.98%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (24.56%)
  • Cancer (15.20%)
  • Breast cancer (15.20%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Cancer, Breast cancer, Internal medicine and Immunology. Massimiliano Bonafè interconnects Molecular biology, Urinary system and Pathology in the investigation of issues within Cancer. The study incorporates disciplines such as Immunohistochemistry, Cancer stem cell, Androgen receptor and ErbB Receptors in addition to Breast cancer.

His Internal medicine research is multidisciplinary, incorporating elements of Endocrinology, Gerontology and Oncology. Many of his studies on Immunology involve topics that are commonly interrelated, such as Mitochondrial DNA. Massimiliano Bonafè studies Immune system, focusing on Immunosenescence in particular.

Between 2015 and 2021, his most popular works were:

  • Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer (221 citations)
  • Self-renewal of CD133 hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer (95 citations)
  • Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. (59 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

His scientific interests lie mostly in Cancer research, Cancer, Immunology, Microvesicles and Breast cancer. Massimiliano Bonafè combines subjects such as Multicellular organism, High Throughput Assay and Anticancer drug with his study of Cancer research. His Cancer research is multidisciplinary, incorporating perspectives in Gerontology, Oncology and Pathology.

His work on Immunosenescence, Immune system and Tumor necrosis factor alpha as part of general Immunology study is frequently connected to Plasminogen activator inhibitor-1, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His study in Microvesicles is interdisciplinary in nature, drawing from both Phenotype, Metastasis, Mitochondrial DNA and Cell biology. His studies deal with areas such as Cancer cell and Cancer stem cell as well as Breast cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Inflamm‐aging: An Evolutionary Perspective on Immunosenescence

Claudio Franceschi;Massimiliano Bonafè;Silvana Valensin;Fabiola Olivieri.
Annals of the New York Academy of Sciences (2006)

4197 Citations

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Pasquale Sansone;Gianluca Storci;Simona Tavolari;Tiziana Guarnieri.
Journal of Clinical Investigation (2007)

846 Citations

Bone Marrow Cells Differentiate in Cardiac Cell Lineages After Infarction Independently of Cell Fusion

Jan Kajstura;Marcello Rota;Brian Whang;Stefano Cascapera.
Circulation Research (2004)

651 Citations

Human immunosenescence: The prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

Claudio Franceschi;Massimiliano Bonafè;Silvana Valensin.
Vaccine (2000)

531 Citations

Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans

Michelangela Barbieri;Massimiliano Bonafè;Claudio Franceschi;Giuseppe Paolisso.
American Journal of Physiology-endocrinology and Metabolism (2003)

519 Citations

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

G. De Benedictis;G. Rose;G. Carrieri;M. De Luca.
The FASEB Journal (1999)

466 Citations

The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

Qing Chang;Eirini Bournazou;Pasquale Sansone;Marjan Berishaj.
Neoplasia (2013)

400 Citations

The network and the remodeling theories of aging: historical background and new perspectives

C Franceschi;S Valensin;M Bonafè;G Paolisso.
Experimental Gerontology (2000)

387 Citations

Centenarians as a model for healthy aging

C. Franceschi;M. Bonafè.
Biochemical Society Transactions (2003)

381 Citations

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity.

Massimiliano Bonafè;Fabiola Olivieri;Luca Cavallone;Simona Giovagnetti.
European Journal of Immunology (2001)

354 Citations

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