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Microbiology

D-Index
52
Citations
8266
World Ranking
4246
National Ranking
291

Overview

Michael Mach is affiliated with the University of Erlangen-Nuremberg in Germany. Their research predominantly focuses on medical science, with specializations in epidemiology, immunology, infectious diseases, hematology, and genetics. The scientist's work has significant contributions in the study of cytomegalovirus and herpesvirus, herpesvirus infections and treatments, hematopoietic stem cell transplantation, virus-based gene therapy research, neonatal health and biochemistry, immunotherapy and immune responses, and Toxoplasma gondii research studies.

Their recent papers showcase a range of topics within virology and immunology. These include:

  • Adult and Cord Blood-Derived High-Affinity gB-CAR-T Cells Effectively React Against Human Cytomegalovirus Infections (2020, Human Gene Therapy)
  • SARS-CoV-2 Spike Protein Is Capable of Inducing Cell-Cell Fusions Independent from Its Receptor ACE2 and This Activity Can Be Impaired by Furin Inhibitors or a Subset of Monoclonal Antibodies (2023, Viruses)
  • Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV (2020, PLoS Pathogens)
  • Neutralizing Antibodies Limit Cell-Associated Spread of Human Cytomegalovirus in Epithelial Cells and Fibroblasts (2022, Viruses)
  • Cell Fusion Induced by a Fusion-Active Form of Human Cytomegalovirus Glycoprotein B (gB) Is Inhibited by Antibodies Directed at Antigenic Domain 5 in the Ectodomain of gB (2020, Journal of Virology)

The scientist frequently collaborates with notable peers in their field. Key coauthors include William J. Britt, Barbara Kropff, Nina Reuter, Thomas Winkler, and Marco Thomas.

Michael Mach publishes in various scientific journals, with repeated contributions to the following venues:

  • Viruses (3 publications)
  • Journal of Virology (3 publications)
  • PLoS Pathogens (2 publications)
  • Human Gene Therapy (1 publication)
  • Annals of Hematology (1 publication)

Their main area of study is medicine, with a bulk of their research grounded in epidemiology. The subfields of epidemiology and immunology are particularly prominent, aligning with their work on virus-related diseases and immune responses.

Best Publications

  • Intrauterine Transmission of Cytomegalovirus to Infants of Women With Preconceptional Immunity

    Suresh B. Boppana;Lisa B. Rivera;Karen B. Fowler;Michael Mach

  • Human cytomegalovirus glycoproteins.

    William J. Britt;Michael Mach

  • Complex Formation by Human Cytomegalovirus Glycoproteins M (gpUL100) and N (gpUL73)

    M. Mach;B. Kropff;P. Dal Monte;W. Britt

  • Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies

    Mats Ohlin;Vivi Anne Sundqvist;Michael Mach;Britta Wahren

  • B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.

    Sonja Pötzsch;Nadja Spindler;Anna-Katharina Wiegers;Tanja Fisch

  • The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific.

    M Urban;W Britt;M Mach

  • Glycoprotein gp116 of human cytomegalovirus contains epitopes for strain-common and strain-specific antibodies

    H. Meyer;V.-A. Sundqvist;L. Pereira;M. Mach

  • Human Cytomegalovirus Infection Elicits a Glycoprotein M (gM)/gN-Specific Virus-Neutralizing Antibody Response

    Masako Shimamura;Michael Mach;William J. Britt

  • Identification of a neutralizing epitope on glycoprotein gp58 of human cytomegalovirus.

    U Utz;W Britt;L Vugler;M Mach

  • The Humoral Immune Response against Human Cytomegalovirus Is Characterized by a Delayed Synthesis of Glycoprotein-Specific Antibodies

    Konrad Schoppel;Barbara Kropff;Christian Schmidt;Rolf Vornhagen

  • Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry.

    Yiquan Wu;Adrian Prager;Simone Boos;Moritz Resch

  • Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus.

    G Jahn;T Kouzarides;M Mach;B C Scholl

  • Dense bodies of human cytomegalovirus induce both humoral and cellular immune responses in the absence of viral gene expression.

    S Pepperl;J Münster;M Mach;J R Harris

  • Protection from CMV infection in immunodeficient hosts by adoptive transfer of memory B cells.

    Karin Klenovsek;Florian Weisel;Andrea Schneider;Uwe Appelt

  • Glycoprotein H of human cytomegalovirus is a major antigen for the neutralizing humoral immune response.

    Urban M;Klein M;Britt Wj;Hassfurther E

  • Activation of Virus-specific Memory B Cells in the Absence of T Cell Help

    Barbara J. Hebeis;Karin Klenovsek;Peter Rohwer;Uwe Ritter

  • UL74 of Human Cytomegalovirus Contributes to Virus Release by Promoting Secondary Envelopment of Virions

    Xiao Jing Jiang;Barbara Adler;Kerstin Laib Sampaio;Margarete Digel

  • Distribution of linear antigenic sites on glycoprotein gp55 of human cytomegalovirus.

    N Kniess;M Mach;J Fay;W J Britt

  • Light chain shuffling of a high affinity antibody results in a drift in epitope recognition

    Mats Ohlin;Henrik Owman;Michael Mach;Carl A.K. Borrebaeck

  • Human cytomegalovirus glycoprotein N (gpUL73-gN) genomic variants: identification of a novel subgroup, geographical distribution and evidence of positive selective pressure

    S. Pignatelli;P. Dal Monte;G. Rossini;S. Chou

Frequent Co-Authors

William J. Britt
William J. Britt University of Alabama at Birmingham
Thomas H. Winkler
Thomas H. Winkler University of Erlangen-Nuremberg
Gerhard Jahn
Gerhard Jahn University of Tübingen
Heinrich Sticht
Heinrich Sticht University of Erlangen-Nuremberg
Carl A. K. Borrebaeck
Carl A. K. Borrebaeck Lund University
Andreas Mackensen
Andreas Mackensen University of Erlangen-Nuremberg
Michael Meyer-Hermann
Michael Meyer-Hermann Technische Universität Braunschweig
Martin Messerle
Martin Messerle Hannover Medical School
Philip G. Stevenson
Philip G. Stevenson University of Queensland
Suresh B. Boppana
Suresh B. Boppana University of Alabama at Birmingham

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