World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
41
Citations
6433
World Ranking
7881
National Ranking
364

Overview

What is she best known for?

The fields of study she is best known for:

  • Genetics
  • Neuron
  • Central nervous system

Isabelle Dusart focuses on Neuroscience, Lesion, Glial scar, Pathology and Spinal cord. The study of Neuroscience is intertwined with the study of Cell biology in a number of ways. Her biological study spans a wide range of topics, including Macrophage and Neuroglia.

Her study in Axon extends to Glial scar with its themes. Her work in Cerebellum tackles topics such as Postsynaptic potential which are related to areas like Axotomy. Her work focuses on many connections between Synaptogenesis and other disciplines, such as Apoptosis, that overlap with her field of interest in Cell.

Her most cited work include:

  • Microglia promote the death of developing Purkinje cells. (509 citations)
  • Secondary Cell Death and the Inflammatory Reaction After Dorsal Hemisection of the Rat Spinal Cord (482 citations)
  • The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion (254 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Neuroscience, Purkinje cell, Cell biology, Cerebellum and Programmed cell death. Her biological study deals with issues like Regeneration, which deal with fields such as Axon, Glial scar and Myelin. Her Purkinje cell study incorporates themes from Hormone and Thyroid.

Her Cell biology research is multidisciplinary, relying on both Oligodendrocyte differentiation and Immunology. Her Cerebellum research includes elements of Neurogenesis and Axotomy. The Spinal cord study combines topics in areas such as Lesion and Pathology.

She most often published in these fields:

  • Neuroscience (68.42%)
  • Purkinje cell (52.63%)
  • Cell biology (47.37%)

What were the highlights of her more recent work (between 2012-2021)?

  • Neuroscience (68.42%)
  • Corticospinal tract (9.21%)
  • Cell biology (47.37%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Neuroscience, Corticospinal tract, Cell biology, Axon guidance and Commissure. Her study on Neurogenesis, Cerebellum and Cerebellar cortex is often connected to Structural organization and Coordinated movement as part of broader study in Neuroscience. Her Cerebellum study combines topics in areas such as Survival rate and Period.

Her studies deal with areas such as Climbing fiber and Purkinje cell as well as Cell biology. Her work carried out in the field of Purkinje cell brings together such families of science as Soma and Dendrite. As part of the same scientific family, Isabelle Dusart usually focuses on Commissure, concentrating on Lateralization of brain function and intersecting with Gait and Corpus callosum.

Between 2012 and 2021, her most popular works were:

  • Consensus Paper: Cerebellar Development. (172 citations)
  • Consensus Paper: Cerebellar Development. (172 citations)
  • The corticospinal tract: Evolution, development, and human disorders (96 citations)

In her most recent research, the most cited papers focused on:

  • Genetics
  • Neuron
  • Central nervous system

Her main research concerns Neuroscience, Cerebellum, Neurogenesis, Structural organization and Soma. Isabelle Dusart mostly deals with Motor skill in her studies of Neuroscience. The study incorporates disciplines such as Axon guidance, Anatomy, Motor control and Brainstem in addition to Motor skill.

Her study in Motor control is interdisciplinary in nature, drawing from both Pyramidal tracts and Spinal cord. Her studies in Soma integrate themes in fields like Climbing fiber, Purkinje cell and Dendrite, Cell biology. Her Metabotropic glutamate receptor 5 study combines topics from a wide range of disciplines, such as Metabotropic glutamate receptor 6, Metabotropic glutamate receptor 7 and Class C GPCR.

Best Publications

  • Microglia promote the death of developing Purkinje cells.

    José Luis Marı́n-Teva;Isabelle Dusart;Catherine Colin;Annie Gervais

  • Secondary Cell Death and the Inflammatory Reaction After Dorsal Hemisection of the Rat Spinal Cord

    I. Dusart;M. E. Schwab

  • Consensus Paper: Cerebellar Development.

    Ketty Leto;Marife Arancillo;Esther B. E. Becker;Annalisa Buffo

  • The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

    Moreau-Fauvarque C;Kumanogoh A;Camand E;Jaillard C

  • The corticospinal tract: Evolution, development, and human disorders

    Quentin Welniarz;Isabelle Dusart;Emmanuel Roze

  • Glial changes following an excitotoxic lesion in the CNS--I. Microglia/macrophages.

    S. Marty;I. Dusart;M. Peschanski

  • Purkinje cell survival and axonal regeneration are age dependent: An in vitro study

    Isabelle Dusart;Matti S. Airaksinen;Constantino Sotelo

  • Glial changes following an excitotoxic lesion in the CNS—II. Astrocytes

    I. Dusart;S. Marty;M. Peschanski

  • Long‐term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord

    Emeline Camand;Emeline Camand;Marie-Pierre Morel;Marie-Pierre Morel;Andréas Faissner;Constantino Sotelo;Constantino Sotelo

  • Intrinsic versus extrinsic determinants during the development of Purkinje cell dendrites

    C. Sotelo;I. Dusart

  • Expression of netrin-1, slit-1 and slit-3 but not of slit-2 after cerebellar and spinal cord lesions.

    Rosine Wehrle;Emeline Camand;Alain Chedotal;Constantino Sotelo

  • Lack of Purkinje cell loss in adult rat cerebellum following protracted axotomy: Degenerative changes and regenerative attempts of the severed axons

    Isabelle Dusart;Constantino Sotelo

  • Retinoid-related orphan receptor alpha controls the early steps of Purkinje cell dendritic differentiation.

    Fatiha Boukhtouche;Sonja Janmaat;Guilan Vodjdani;Vanessa Gautheron

  • Late axonal sprouting of injured Purkinje cells and its temporal correlation with permissive changes in the glial scar.

    Isabelle Dusart;Marie Pierre Morel;Rosine Wehrlé;Constantino Sotelo

  • Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum

    A. M. Ghoumari;I. Dusart;M. El-Etr;F. Tronche

  • RAD51 haploinsufficiency causes congenital mirror movements in humans.

    Christel Depienne;Delphine Bouteiller;Aurélie Méneret;Ségolène Billot

  • Purkinje cell death: differences between developmental cell death and neurodegenerative death in mutant mice.

    Isabelle Dusart;Jean Louis Guenet;Constantino Sotelo

  • Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors.

    Visou Ady;Julie Perroy;Julie Perroy;Ludovic Tricoire;Claire Piochon

  • Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and kruppel-like factor 9 in Purkinje cells.

    Hasan X. Avci;Clement Lebrun;Rosine Wehrlé;Mohamed Doulazmi

  • Inhibition of Protein Kinase C Prevents Purkinje Cell Death But Does Not Affect Axonal Regeneration

    Abdel M. Ghoumari;Rosine Wehrlé;Chris I. De Zeeuw;Constantino Sotelo

  • Stathmin: cellular localization of a major phosphoprotein in the adult rat and human CNS.

    Marc Peschanski;Etienne Hirsch;Isabelle Dusart;Valérie Doye

Frequent Co-Authors

Constantino Sotelo
Constantino Sotelo Sorbonne University
Marc Peschanski
Marc Peschanski Grenoble Alpes University
Jean Mariani
Jean Mariani Sorbonne University
Alain Chédotal
Alain Chédotal Institut de la Vision
Laure Rondi-Reig
Laure Rondi-Reig Centre national de la recherche scientifique, CNRS
Sabine Meunier
Sabine Meunier Université Paris Cité
Christel Depienne
Christel Depienne Essen University Hospital
William B. Dobyns
William B. Dobyns University of Minnesota
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital
Alexis Brice
Alexis Brice Institut du Cerveau

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