What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary areas of investigation include Internal medicine, Endocrinology, Molecular biology, ADP-ribosyl Cyclase and Cyclic ADP-ribose.
Hiroshi Okamoto is interested in Islet, which is a field of Endocrinology.
His Molecular biology study integrates concerns from other disciplines, such as Complementary DNA, Genetics, Gene, Northern blot and Pancreatic islets.
His studies deal with areas such as Biochemistry and Cyclase as well as ADP-ribosyl Cyclase.
His research in Cyclic ADP-ribose intersects with topics in Biophysics, Depolarization, Ca2 release and Caffeine.
His RAGE research is multidisciplinary, incorporating elements of Albuminuria and Diabetic nephropathy.
His most cited work include:
- Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. (565 citations)
- CD38 is critical for social behaviour by regulating oxytocin secretion (487 citations)
- Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice (427 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Internal medicine, Molecular biology, Endocrinology, Cyclic ADP-ribose and Biochemistry.
His work investigates the relationship between Internal medicine and topics such as Autoantibody that intersect with problems in Type 1 diabetes.
Hiroshi Okamoto has researched Molecular biology in several fields, including Gene expression, In situ hybridization, Complementary DNA, cDNA library and Gene.
His Endocrinology study focuses mostly on Insulin, Islet, Pancreatic islets, Diabetes mellitus and RAGE.
His work carried out in the field of Diabetes mellitus brings together such families of science as Autoimmunity and Immunology.
His Cyclic ADP-ribose study combines topics from a wide range of disciplines, such as Ryanodine receptor, Cyclase, Second messenger system, ADP-ribosyl Cyclase and NAD+ kinase.
He most often published in these fields:
- Internal medicine (32.30%)
- Molecular biology (29.19%)
- Endocrinology (27.95%)
What were the highlights of his more recent work (between 2005-2020)?
- Internal medicine (32.30%)
- Endocrinology (27.95%)
- Molecular biology (29.19%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Internal medicine, Endocrinology, Molecular biology, Immunology and Cyclic ADP-ribose.
His studies examine the connections between Internal medicine and genetics, as well as such issues in Cardiology, with regards to Incidence.
His study in Young adult extends to Endocrinology with its themes.
He combines subjects such as Signal transduction and Messenger RNA, Alternative splicing with his study of Molecular biology.
His Immunology research incorporates themes from Severe combined immunodeficiency and Transplantation.
His Cyclic ADP-ribose research includes themes of Ryanodine receptor and Intracellular.
Between 2005 and 2020, his most popular works were:
- CD38 is critical for social behaviour by regulating oxytocin secretion (487 citations)
- RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. (198 citations)
- Trichostatin A, an Inhibitor of Histone Deacetylase, Inhibits Smooth Muscle Cell Proliferation via Induction of p21WAF1 (80 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Hiroshi Okamoto mainly investigates Internal medicine, Endocrinology, Cell growth, RAGE and Autocrine signalling.
His Internal medicine research is multidisciplinary, relying on both Downregulation and upregulation and Streptozotocin.
His research is interdisciplinary, bridging the disciplines of Dialysis and Endocrinology.
His Cell growth research is multidisciplinary, incorporating perspectives in Regulator, Kinase and Phosphorylation.
His RAGE study incorporates themes from Retinopathy, Angiogenesis, Messenger RNA and Nephropathy.
As a part of the same scientific family, Hiroshi Okamoto mostly works in the field of Autocrine signalling, focusing on Signal transduction and, on occasion, Molecular biology.
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