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Immunology

D-Index
102
Citations
36598
World Ranking
678
National Ranking
22

Medicine

D-Index
104
Citations
37337
World Ranking
7095
National Ranking
206

Overview

Kenneth G. C. Smith is affiliated with the University of Cambridge in the United Kingdom. Their research focuses primarily on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Within these areas, subfields include infectious diseases, immunology, genetics, molecular biology, and neurology.

The scientist has contributed extensively to the study of SARS-CoV-2 and COVID-19, including clinical research investigations and analysis of the long-term effects of COVID-19. Their research also covers immune cell function and interaction, inflammatory bowel disease, immunodeficiency, autoimmune disorders, and the immunology of T-cell and B-cell responses.

Key recent publications include:

  • "Single-cell multi-omics analysis of the immune response in COVID-19" (2021, Nature Medicine)
  • "Whole-genome sequencing of patients with rare diseases in a national health system" (2020, Nature)
  • "A thermostable, closed SARS-CoV-2 spike protein trimer" (2020, Nature Structural & Molecular Biology)
  • "Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease" (2021, Immunity)
  • "A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial" (2024, The Lancet. Gastroenterology & Hepatology)

Frequent coauthors collaborating with Kenneth G. C. Smith include:

  • Paul Lyons
  • John R. Bradley
  • Laura Bergamaschi
  • Eoin McKinney
  • Federica Mescia

Publications often appear in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes Care
  • SSRN Electronic Journal
  • Nature Immunology
  • Cell Reports

Their research spans multiple topics including:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Immune Cell Function and Interaction
  • Inflammatory Bowel Disease
  • Immunodeficiency and Autoimmune Disorders
  • T-cell and B-cell Immunology

Best Publications

  • Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

    Unknown

  • Foxp3+ follicular regulatory T cells control the germinal center response

    Michelle A. Linterman;Wim Pierson;Sau K. Lee;Axel Kallies

  • Competence and competition : the challenge of becoming a long-lived plasma cell

    Andreas Radbruch;Gwendolin Muehlinghaus;Elke O. Luger;Ayako Inamine

  • Genetically Distinct Subsets within ANCA-Associated Vasculitis

    Paul A Lyons;Tim F Rayner;Sapna Trivedi;Julia U Holle

  • Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer.

    E.R. Horak;N. Klenk;R. Leek;S. LeJeune

  • microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells

    Elena Vigorito;Kerry L. Perks;Cei Abreu-Goodger;Sam Bunting

  • SARS-CoV-2 evolution during treatment of chronic infection.

    Steven A. Kemp;Dami A. Collier;Dami A. Collier;Rawlings P. Datir;Isabella A. T. M. Ferreira

  • Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2.

    Dami A Collier;Dami A Collier;Isabella A T M Ferreira;Prasanti Kotagiri;Rawlings P Datir;Rawlings P Datir

  • T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

    Eoin F. McKinney;James C. Lee;David R. W. Jayne;Paul A. Lyons

  • FcγRIIB in autoimmunity and infection: evolutionary and therapeutic implications

    Kenneth G. C. Smith;Menna R. Clatworthy

  • Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

    Dami A. Collier;Dami A. Collier;Anna De Marco;Isabella A. T. M. Ferreira;Bo Meng

  • Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission.

    Lucy Rivett;Lucy Rivett;Sushmita Sridhar;Sushmita Sridhar;Dominic Sparkes;Dominic Sparkes;Matthew Routledge;Matthew Routledge

  • Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment.

    K. G. C. Smith;R. B. Jones;S. M. Burns;D. R. W. Jayne

  • The extent of affinity maturation differs between the memory and antibody‐forming cell compartments in the primary immune response

    Ken G C Smith;Amanda Light;Gustav Victor Joseph Nossal;David Tarlinton

  • A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

    Kim Newton;Alan W. Harris;Mary L. Bath;Kenneth G.C. Smith

  • The phenotype and fate of the antibody‐forming cells of the splenic foci

    Kenneth G. C. Smith;Timothy D. Hewitson;G. J. V. Nossal;David M. Tarlinton

  • A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis

    Rachel B. Jones;Alastair J. Ferraro;Afzal N. Chaudhry;Paul Brogan

  • A CD8 + T cell transcription signature predicts prognosis in autoimmune disease

    Eoin F McKinney;Paul A Lyons;Edward J Carr;Jane L Hollis

  • Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

    Ball Pulendran;George Kannourakis;Sara Nouri;Kenneth G. C. Smith;Kenneth G. C. Smith

  • Whole-genome sequencing of patients with rare diseases in a national health system

    Ernest Turro;William J Astle;Karyn Megy;Stefan Graf

  • Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts.

    R Andres Floto;Menna R Clatworthy;Karen R Heilbronn;Dalya R Rosner

  • Foxp3(+) follicular regulatory T cells control the germinal centre response

    M. A Linterman;Wim Pierson;S. K Lee;A Kallies

Frequent Co-Authors

Paul A. Lyons
Paul A. Lyons University of Cambridge
James Lee
James Lee The Francis Crick Institute
Menna R. Clatworthy
Menna R. Clatworthy University of Cambridge
David M. Tarlinton
David M. Tarlinton Monash University
Gordon Dougan
Gordon Dougan University of Cambridge
David Jayne
David Jayne University of Cambridge
Michelle A. Linterman
Michelle A. Linterman Babraham Institute
Peter J. Friend
Peter J. Friend University of Oxford
Paul J. Lehner
Paul J. Lehner University of Cambridge
Paul A. MacAry
Paul A. MacAry National University of Singapore

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