World's Best Scientists 2026 revealed!
Nobuhisa Iwata

Nobuhisa Iwata

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
19654
World Ranking
11136
National Ranking
764

Nobuhisa Iwata publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Nobuhisa Iwata sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 170 publications — 36th percentile

36% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Nobuhisa Iwata D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Nobuhisa Iwata sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 61 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Nobuhisa Iwata is affiliated with Nagasaki University in Japan and primarily conducts research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Physiology, Neurology, Immunology, Cellular and Molecular Neuroscience, and Genetics.

The scientist's research encompasses a range of main topics such as:

  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Computational Drug Discovery Methods
  • Genetics and Neurodevelopmental Disorders
  • Galectins and Cancer Biology
  • Macrophage Migration Inhibitory Factor

Nobuhisa Iwata has contributed to several recent papers, including:

  • "Recent Advances in the Modeling of Alzheimer's Disease", 2022, Frontiers in Neuroscience
  • "Galectin 3-binding protein suppresses amyloid-β production by modulating β-cleavage of amyloid precursor protein", 2020, Journal of Biological Chemistry
  • "The dopaminergic system promotes neprilysin-mediated degradation of amyloid-β in the brain", 2024, Science Signaling
  • "Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice", 2020, npj Vaccines
  • "The role of TREM2 N-glycans in trafficking to the cell surface and signal transduction of TREM2", 2022, The Journal of Biochemistry

In their publishing record, the most frequent venues where work has appeared include:

  • The Journal of Biochemistry
  • Biological and Pharmaceutical Bulletin
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Neuroscience
  • Science Signaling

Nobuhisa Iwata collaborates regularly with several researchers, with the most frequent co-authors being:

  • Keiro Shirotani
  • Takaomi C. Saido
  • Kaori Watanabe
  • Naoto Watamura
  • Daisuke Hatta

Best Publications

  • Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

    Yasumasa Yoshiyama;Makoto Higuchi;Bin Zhang;Shu-Ming Huang

  • Metabolic Regulation of Brain Aβ by Neprilysin

    Nobuhisa Iwata;Satoshi Tsubuki;Yoshie Takaki;Keiro Shirotani

  • Single App knock-in mouse models of Alzheimer's disease

    Takashi Saito;Yukio Matsuba;Naomi Mihira;Jiro Takano

  • Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition.

    Nobuhisa Iwata;Satoshi Tsubuki;Yoshie Takaki;Kaori Watanabe

  • Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

    Takayuki Kondo;Masashi Asai;Masashi Asai;Kayoko Tsukita;Yumiko Kutoku

  • Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

    Masahiro Maruyama;Hitoshi Shimada;Tetsuya Suhara;Hitoshi Shinotoh

  • Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.

    Takashi Saito;Nobuhisa Iwata;Satoshi Tsubuki;Yoshie Takaki

  • 19F and 1H MRI detection of amyloid beta plaques in vivo.

    Makoto Higuchi;Nobuhisa Iwata;Yukio Matsuba;Kumi Sato

  • Aβ Secretion and Plaque Formation Depend on Autophagy

    Per Nilsson;Krishnapriya Loganathan;Misaki Sekiguchi;Yukio Matsuba

  • Reply to: 'Clearance of amyloid β-peptide from brain: transport or metabolism?'

    Nobuhisa Iwata;Satoshi Tsubuki;Emi Hama;Yoshie Takaki

  • Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography

    Jun Maeda;Bin Ji;Toshiaki Irie;Takami Tomiyama

  • Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

    Keiro Shirotani;Satoshi Tsubuki;Nobuhisa Iwata;Yoshie Takaki

  • Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain

    Nobuhisa Iwata;Hiroaki Mizukami;Keiro Shirotani;Yoshie Takaki

  • Potent amyloidogenicity and pathogenicity of Aβ43

    Takashi Saito;Takahiro Suemoto;Nathalie Brouwers;Kristel Sleegers

  • Metabolism of amyloid-β peptide and Alzheimer's disease

    Nobuhisa Iwata;Makoto Higuchi;Takaomi C. Saido

  • Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.

    Chiho Hirata-Fukae;Hui Fang Li;Hyang Sook Hoe;Audrey J. Gray

  • The potential role of amyloid βin the pathogenesis of age-related macular degeneration

    Takeshi Yoshida;Kyoko Ohno-Matsui;Shizuko Ichinose;Tetsuji Sato

  • Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

    Nobuhisa Iwata;Yoshie Takaki;Shinjiro Fukami;Shinjiro Fukami;Satoshi Tsubuki

  • Neprilysin-sensitive Synapse-associated Amyloid-β Peptide Oligomers Impair Neuronal Plasticity and Cognitive Function *

    Shu Ming Huang;Akihiro Mouri;Hideko Kokubo;Hideko Kokubo;Ryuichi Nakajima

  • Calpain Mediates Excitotoxic DNA Fragmentation via Mitochondrial Pathways in Adult Brains EVIDENCE FROM CALPASTATIN MUTANT MICE

    Jiro Takano;Masanori Tomioka;Satoshi Tsubuki;Makoto Higuchi

Frequent Co-Authors

Takaomi C. Saido
Takaomi C. Saido RIKEN Center for Brain Science
Makoto Higuchi
Makoto Higuchi National Institutes for Quantum and Radiological Science and Technology
Takashi Saito
Takashi Saito Nagoya City University
Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Toshiji Mukai
Toshiji Mukai Kobe University
Yukihiro Noda
Yukihiro Noda Meijo University
Tetsuya Suhara
Tetsuya Suhara National Institutes for Quantum and Radiological Science and Technology
Shoichi Ishiura
Shoichi Ishiura University of Tokyo
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Shin-ichi Muramatsu
Shin-ichi Muramatsu Jichi Medical University

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