What is he best known for?
The fields of study he is best known for:
- Enzyme
- Internal medicine
- Biochemistry
His main research concerns Biochemistry, Glutathione, Oxidative stress, Internal medicine and Cytotoxicity.
His study in Reactive oxygen species, Hepatocyte, Mitochondrion, Antioxidant and Metabolism is done as part of Biochemistry.
His Antioxidant study combines topics from a wide range of disciplines, such as Toxicity and Folk medicine.
His work deals with themes such as Lipid peroxidation, Autoxidation, Peroxidase, Meclofenamic acid and Redox, which intersect with Glutathione.
His Oxidative stress study incorporates themes from Glyoxal, Metabolite, Glycation and Pharmacology, Tolfenamic acid.
His Internal medicine study combines topics in areas such as Endocrinology, Sorbitol dehydrogenase and Cardiology.
His most cited work include:
- Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia (1203 citations)
- Molecular mechanisms of quinone cytotoxicity. (849 citations)
- Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. (763 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Biochemistry, Glutathione, Cytotoxicity, Internal medicine and Oxidative stress.
His Biochemistry study frequently draws connections between adjacent fields such as Pharmacology.
Radical and Photochemistry is closely connected to Peroxidase in his research, which is encompassed under the umbrella topic of Glutathione.
His Cytotoxicity research is multidisciplinary, incorporating perspectives in In vivo, Toxicity, High-content screening and Metabolism.
The study incorporates disciplines such as Endocrinology and Cardiology in addition to Internal medicine.
His Oxidative stress research incorporates themes from Metabolite, Glycation, Glyoxal and Methylglyoxal.
He most often published in these fields:
- Biochemistry (50.78%)
- Glutathione (25.39%)
- Cytotoxicity (25.08%)
What were the highlights of his more recent work (between 2007-2020)?
- Biochemistry (50.78%)
- Cytotoxicity (25.08%)
- Oxidative stress (17.87%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Biochemistry, Cytotoxicity, Oxidative stress, Pharmacology and Internal medicine.
His study in Reactive oxygen species, Glutathione, Protein Carbonylation, Lipid peroxidation and Hepatocyte falls under the purview of Biochemistry.
His study in Glutathione is interdisciplinary in nature, drawing from both Reactivity, Autoxidation, Aldehyde dehydrogenase and Electrophile.
The various areas that Peter J. O'Brien examines in his Cytotoxicity study include In vivo, Caco-2, Intracellular and High-content screening.
His research integrates issues of Metabolite, Toxicity and Metabolism in his study of Oxidative stress.
He combines subjects such as Gastroenterology, Cardiology, Endocrinology and Pathology with his study of Internal medicine.
Between 2007 and 2020, his most popular works were:
- Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity. (199 citations)
- Design of Hybrid MnO2‐Polymer‐Lipid Nanoparticles with Tunable Oxygen Generation Rates and Tumor Accumulation for Cancer Treatment (117 citations)
- Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model. (100 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Internal medicine
- Biochemistry
Peter J. O'Brien mainly focuses on Biochemistry, Glutathione, Cytotoxicity, Protein Carbonylation and Oxidative stress.
His work in Reactive oxygen species, Methylglyoxal, Lipid peroxidation, Glycation and Metabolite is related to Biochemistry.
His Glutathione research includes themes of Catalase, Electrophile, Aldehyde dehydrogenase and Reactivity.
His Cytotoxicity research is multidisciplinary, incorporating elements of Toxicity, Caco-2, Pharmacology and High-content screening.
His Protein Carbonylation research integrates issues from Glyoxal, Hepatocyte and Bovine serum albumin.
His Hepatocyte research is multidisciplinary, relying on both Peroxidase and Ferritin.
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