Akira Nagafuchi

Overview

Best Publications

• Occludin: a novel integral membrane protein localizing at tight junctions.

  M Furuse;T Hirase;M Itoh;A Nagafuchi

  3157
  Citations

• Cell binding function of E-cadherin is regulated by the cytoplasmic domain.

  A Nagafuchi;M Takeichi

  1171
  Citations

• Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

  M Furuse;M Itoh;T Hirase;A Nagafuchi

  1147
  Citations

• Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

  Akira Nagafuchi;Yasuaki Shirayoshi;Kenji Okazaki;Kunio Yasuda

  1048
  Citations

• alpha-Catenin as a tension transducer that induces adherens junction development.

  Shigenobu Yonemura;Yuko Wada;Toshiyuki Watanabe;Akira Nagafuchi

  1036
  Citations

• Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments.

  Masahiko Itoh;Akira Nagafuchi;Seiji Moroi;Shoichiro Tsukita

  967
  Citations

• Expressed recombinant cadherins mediate cell sorting in model systems.

  Akinao Nose;Akira Nagafuchi;Masatoshi Takeichi

  946
  Citations

• The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy.

  M Itoh;A Nagafuchi;S Yonemura;T Kitani-Yasuda

  819
  Citations

• Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.

  N Matsuyoshi;M Hamaguchi;S Taniguchi;A Nagafuchi

  752
  Citations

• The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression

  Akira Nagafuchi;Masatoshi Takeichi;Shoichiro Tsukita

  722
  Citations

• Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

  A Nagafuchi;M Takeichi

  607
  Citations

• The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules.

  A Nagafuchi;S Ishihara;S Tsukita

  571
  Citations

• Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family.

  Kohei Hatta;Akinao Nose;Akira Nagafuchi;Masatoshi Takeichi

  531
  Citations

• Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.

  Mitsuko Watabe;Akira Nagafuchi;Sachiko Tsukita;Masatoshi Takeichi

  510
  Citations

• Cadherin Dysfunction in a Human Cancer Cell Line: Possible Involvement of Loss of α-Catenin Expression in Reduced Cell-Cell Adhesiveness

  Yutaka Shimoyama;Akira Nagafuchi;Shin Fujita;Masahiro Gotoh

  488
  Citations

• Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells

  Shigenobu Yonemura;Masahiko Itoh;Akira Nagafuchi;Shoichiro Tsukita

  484
  Citations

• A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

  N. Sato;N. Funayama;A. Nagafuchi;S. Yonemura

  460
  Citations

• Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions.

  Shoichiro Tsukita;Sachiko Tsukita;Akira Nagafuchi;Shigenobu Yonemura

  454
  Citations

• Reduction of E-Cadherin Levels and Deletion of the α-Catenin Gene in Human Prostate Cancer Cells

  Ronald A. Morton;Charles M. Ewing;Charles M. Ewing;Akira Nagafuchi;Shoichiro Tsukita

  440
  Citations

• α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells

  Mitsuko Watabe-Uchida;Naoshige Uchida;Yuzo Imamura;Akira Nagafuchi

  426
  Citations