World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
52
Citations
8243
World Ranking
13669
National Ranking
370

Molecular Biology

D-Index
52
Citations
8310
World Ranking
2451
National Ranking
77

Overview

Jeremy S. Lee is affiliated with the University of Saskatchewan in Canada and specializes in the field of Medicine, with a focus on Neurology and related subfields. Their work encompasses several interdisciplinary areas including Cellular and Molecular Neuroscience, Physiology, Organic Chemistry, and Polymers and Plastics.

Lee's research primarily addresses mechanisms and treatments related to Parkinson's Disease, a major topic within their portfolio. Additional key topics include neurological disorders and treatments, conducting polymers and applications, adenosine and purinergic signaling pathways, neuroscience and neuropharmacology research, and the applications of click chemistry.

Notable recent papers authored by or involving Lee include:

  • "Adenosine A1 receptor ligands bind to α-synuclein: implications for α-synuclein misfolding and α-synucleinopathy in Parkinson's disease," 2022, published in Translational Neurodegeneration
  • "Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds," 2021, published in Xenobiotica
  • "An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds," 2022, published in Xenobiotica

Frequent coauthors in Lee's research include Chukwunonso K. Nwabufo, Omozojie P. Aigbogun, Kevin J. Allen, Madeline N. Owens, and Christopher P. Phenix. These collaborations reflect a consistent team dynamic in Lee's investigative projects.

Their publications have appeared most frequently in the journals Xenobiotica and Translational Neurodegeneration. These venues indicate a focus on pharmacological, biochemical, and neurological aspects of their research interests.

Jeremy S. Lee's research contributions engage with complex biochemical and neurological mechanisms, particularly those related to Parkinson's disease pathology and diagnostics, as evidenced by their focus on α-synuclein binding compounds and metabolic probe design.

Best Publications

  • Metallic Conduction through Engineered DNA: DNA Nanoelectronic Building Blocks

    A. Rakitin;P. Aich;C. Papadopoulos;Yu. Kobzar

  • Review: ethidium fluorescence assays. Part 1. Physicochemical studies.

    A.R. Morgan;J.S. Lee;D.E. Pulleyblank;N.L. Murray

  • Poly(pyrimidine) poly(purine) synthetic DNAs containing 5-methylcytosine form stable triplexes at neutral pH

    J S Lee;M L Woodsworth;L J Latimer;A R Morgan

  • Transport of α-Helical Peptides through α-Hemolysin and Aerolysin Pores†

    Radu Stefureac;Yi-Tao Long;Heinz-Bernhard Kraatz;Peter Howard

  • M-DNA: A complex between divalent metal ions and DNA which behaves as a molecular wire.

    Palok Aich;Shaunivan L. Labiuk;Les W. Tari;Louis J.T. Delbaere

  • Complexes formed by (pyrimidine)n . (purine)n DNAs on lowering the pH are three-stranded.

    Jeremy S. Lee;Douglas A. Johnson;A. Richard Morgan

  • Structure of Peptides Investigated by Nanopore Analysis

    Todd C. Sutherland;Yi-Tao Long;Radu-Ioan Stefureac;Irene Bediako-Amoa

  • A cooperative conformational change in duplex DNA induced by Zn2+ and other divalent metal ions

    J. S. Lee;L. J. P. Latimer;R. S. Reid

  • Polyamines favor DNA triplex formation at neutral pH.

    Ken J. Hampel;Paul Crosson;Jeremy S. Lee

  • Coralyne binds tightly to both T.A.T- and C.G.C(+)-containing DNA triplexes.

    Jeremy S. Lee;Laura J. P. Latimer;Ken J. Hampel

  • Molecular mechanisms of binding and single-strand scission of DNA by the antitumor antibiotics saframycins A and C

    J. William Lown;Alummoottil V. Joshua;Jeremy S. Lee

  • AC impedance spectroscopy of native DNA and M-DNA.

    Yi-Tao Long;Chen-Zhong Li;Heinz-Bernhard Kraatz;Jeremy S. Lee

  • Electrochemical detection of single-nucleotide mismatches: application of M-DNA.

    Yi-Tao Long;Chen-Zhong Li;Todd C. Sutherland;Heinz-Bernhard Kraatz

  • A monoclonal antibody to triplex DNA binds to eucaryotic chromosomes.

    Jeremy S. Lee;Gary D. Burkholder;Laura J.P. Latimer;Brenda L. Haug

  • Evaluation of mutagenesis for epitope mapping. Structure of an antibody-protein antigen complex.

    Lata Prasad;Sadhana Sharma;M. Vandonselaar;J. W. Quail

  • Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies.

    Mizuki Ohno;Tatsuo Fukagawa;Jeremy S. Lee;Toshimichi Ikemura

  • Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation.

    Sathees C. Raghavan;Paul Chastain;Jeremy S. Lee;Balachandra G. Hegde

  • Triplex DNA in the nucleus: direct binding of triplex-specific antibodies and their effect on transcription, replication and cell growth.

    Yehenew M. Agazie;Gary D. Burkholder;Jeremy S. Lee

  • A Comparison of Electron-Transfer Rates of Ferrocenoyl-Linked DNA

    Yi-Tao Long;Chen-Zhong Li;Todd C. Sutherland;M'Hamed Chahma

  • The stability of polypurine tetraplexes in the presence of mono- and divalent cations

    Jeremy S. Lee

  • Antibodies to DNA

    Wayne F. Anderson;Miroslaw Cygler;Ralph P. Braun;Jeremy S. Lee

Frequent Co-Authors

Heinz-Bernhard Kraatz
Heinz-Bernhard Kraatz University of Toronto
Yi-Tao Long
Yi-Tao Long Nanjing University
Chen-Zhong Li
Chen-Zhong Li Chinese University of Hong Kong, Shenzhen
Wayne F. Anderson
Wayne F. Anderson Northwestern University
Neil R. Cashman
Neil R. Cashman University of British Columbia
Tim R. Mosmann
Tim R. Mosmann University of Rochester Medical Center
Thekkumkat Thomas
Thekkumkat Thomas Rutgers, The State University of New Jersey
Miroslaw Cygler
Miroslaw Cygler University of Saskatchewan
Jan Balzarini
Jan Balzarini KU Leuven
Jimmy Xu
Jimmy Xu Brown University

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