2026 Patrizia Mecocci: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Best Female Scientists	113	772	738	15	15	533	50528
Medicine	115	4497	4219	135	124	515	55584

Research.com Recognitions

2025 - Research.com Best Female Scientists Award

Overview

Patrizia Mecocci is affiliated with the University of Perugia in Italy. Their research primarily focuses on medical science with a strong emphasis on neurodegenerative diseases, particularly Alzheimer's disease. Their work spans various subfields including physiology, psychiatry and mental health, molecular biology, genetics, and neurology.

The scientist has made notable contributions to the understanding of dementia and cognitive impairment, with a significant portion of their research dedicated to Alzheimer's disease and related treatments. Their main topics of research include:

Dementia and Cognitive Impairment Research
Alzheimer's disease research and treatments
Genetic Associations and Epidemiology
Diet and metabolism studies
Geriatric Care and Nursing Homes
Frailty in Older Adults
Tryptophan and brain disorders

Patrizia Mecocci has published extensively in several well-known academic venues. The most frequent publication venues include:

Alzheimer s & Dementia
Aging Clinical and Experimental Research
Journal of Alzheimer s Disease
Nutrients
bioRxiv (Cold Spring Harbor Laboratory)

Their recent research papers demonstrate the range and focus of their work. Selected recent publications include:

"The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease" (2021), Alzheimer's & Dementia
"Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease" (2022), Nature Genetics
"The reliability of a deep learning model in clinical out-of-distribution MRI data: A multicohort study" (2020), Medical Image Analysis
"Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer's disease" (2021), Alzheimer's Research & Therapy
"Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders" (2021), Genome Biology

The scientist frequently collaborates with other researchers in the field. Among their frequent co-authors are:

Virginia Boccardi
Magda Tsolaki
Hilkka Soininen
Philip Scheltens
Davide Seripa

With a total of 184 publications in medicine, the scope of Patrizia Mecocci's work covers extensive research efforts across multiple intersecting domains of neurodegeneration, genetics, metabolism, and clinical applications. Their contributions support ongoing exploration of diagnostic biomarkers, genetic risk factors, metabolic changes, and neuroimaging approaches in Alzheimer's disease and other neurodegenerative disorders.

Best Publications

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

4855
Citations
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

P Mecocci;U MacGarvey;M F Beal

1611
Citations
Alzheimer's disease: clinical trials and drug development

Francesca Mangialasche;Francesca Mangialasche;Alina Solomon;Alina Solomon;Bengt Winblad;Patrizia Mecocci

1538
Citations
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

1401
Citations
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

1090
Citations
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain

P Mecocci;U MacGarvey;A E Kaufman;D Koontz

999
Citations
Common genetic variants influence human subcortical brain structures.

Derrek P. Hibar;Jason L. Stein;Jason L. Stein;Miguel E. Renteria;Alejandro Arias-Vasquez

933
Citations
Oxidative stress in brain aging, neurodegenerative and vascular diseases : An overview

E. Mariani;M.C. Polidori;A. Cherubini;P. Mecocci

872
Citations
Clinical trials and late-stage drug development for Alzheimer's disease : an appraisal from 1984 to 2014

Lon S. Schneider;Francesca Mangialasche;Francesca Mangialasche;Niels Andreasen;Niels Andreasen;Howard Feldman

832
Citations
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer’s disease

P. Rinaldi;M.C. Polidori;A. Metastasio;E. Mariani

739
Citations
Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review.

Katrin Jekel;Marinella Damian;Carina Wattmo;Lucrezia Hausner

665
Citations
Marked Decrease in Plasma Antioxidants in Aged Osteoporotic Women: Results of a Cross-Sectional Study

Dario Maggio;Mauro Barabani;Marco Pierandrei;M. Cristina Polidori

631
Citations
Potential markers of oxidative stress in stroke.

Antonio Cherubini;Carmelinda Ruggiero;M. Cristina Polidori;Patrizia Mecocci

596
Citations
Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle

Patrizia Mecocci;Giorgio Fanó;Stefania Fulle;Usha MacGarvey

580
Citations
Neuropsychiatric syndromes in dementia: Results from the European Alzheimer disease Consortium: Part I

Pauline Aalten;Frans R.J. Verhey;Marina Boziki;Roger Bullock

504
Citations
Validation of the five-item geriatric depression scale in elderly subjects in three different settings

Patrizia Rinaldi;Patrizia Mecocci;Claudia Benedetti;Sara Ercolani

503
Citations
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

Madhav Thambisetty;Andrew Simmons;Latha Velayudhan;Abdul Hye

501
Citations
Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.

Stephanie J B Vos;Frans Verhey;Lutz Frölich;Johannes Kornhuber

413
Citations
Plasma antioxidants and longevity: a study on healthy centenarians.

Patrizia Mecocci;M.Cristina Polidori;Leonarda Troiano;Antonio Cherubini

404
Citations
Antioxidant Profile and Early Outcome in Stroke Patients

Antonio Cherubini;Maria Cristina Polidori;Mario Bregnocchi;Salvatore Pezzuto

388
Citations

Frequent Co-Authors

Simon Lovestone University of Oxford

Hilkka Soininen University of Eastern Finland

Magda Tsolaki Aristotle University of Thessaloniki

Andrew Simmons King's College London

Bruno Vellas Federal University of Toulouse Midi-Pyrénées

Eric Westman Karolinska Institute

Antonio Cherubini University of Perugia

Lars-Olof Wahlund Karolinska Institute

Christian Spenger Karolinska Institute

John Powell King's College London

External Links

Personal website of Patrizia Mecocci

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