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Biology and Biochemistry

D-Index
68
Citations
13630
World Ranking
7942
National Ranking
585

Overview

Wolfgang A. Schulz is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with an emphasis on molecular biology within these areas. Schulz's scholarly activity also touches on subfields such as surgery, plant science, oncology, and law.

Their main research topics include:

  • Epigenetics and DNA Methylation
  • Histone Deacetylase Inhibitors Research
  • Bladder and Urothelial Cancer Treatments
  • RNA modifications and cancer
  • Chromosomal and Genetic Variations
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors

Frequent co-authors collaborating with Schulz consist of:

  • Michèle J. Hoffmann
  • Günter Niegisch
  • Karl Köhrer
  • Patcharawalai Whongsiri
  • Patrick Petzsch

Schulz has published numerous papers across multiple scientific journals, with a higher concentration in journals such as Cancers and the International Journal of Molecular Sciences. Other notable publication venues include Scientific Reports, Zenodo (CERN European Organization for Nuclear Research), and Anticancer Research. Examples of recent publications include:

  • Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1, 2020, Cancers
  • Alterations of Chromatin Regulators in the Pathogenesis of Urinary Bladder Urothelial Carcinoma, 2021, Cancers
  • Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells, 2021, Genes
  • Many Different LINE-1 Retroelements Are Activated in Bladder Cancer, 2020, International Journal of Molecular Sciences
  • In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi), 2020, International Journal of Molecular Sciences

Best Publications

  • Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen

    Thomas P. A. Devasagayam;Steen Steenken;Maik S. W. Obendorf;Wolfgang A. Schulz

  • Tumour class prediction and discovery by microarray-based DNA methylation analysis

    Péter Adorján;Jürgen Distler;Evelyne Lipscher;Fabian Model

  • DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas.

    A R Florl;R Löwer;B J Schmitz-Dräger;W A Schulz

  • Causes and consequences of DNA hypomethylation in human cancer.

    Michèle J Hoffmann;Wolfgang A Schulz

  • Methylation of endogenous human retroelements in health and disease.

    W. A. Schulz;Christine Steinhoff;A. R. Florl

  • Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation.

    A R Florl;C Steinhoff;M. M. L. Müller;H-H Seifert

  • Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignancies.

    Wolfgang A. Schulz;Angelika Krummeck;Ingrid Rösinger;Peter Eickelmann

  • High frequency of alterations in DNA methylation in adenocarcinoma of the prostate.

    Simon Santourlidis;Andrea Florl;Rolf Ackermann;Hans-Christian Wirtz

  • Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma.

    Wolfgang A. Schulz;Jussi P. Elo;Andrea R. Florl;Sari Pennanen

  • Hypomethylation of L1 LINE sequences prevailing in human urothelial carcinoma.

    Bettina Jürgens;Bernd J. Schmitz-Dräger;Wolfgang A. Schulz

  • Understanding urothelial carcinoma through cancer pathways.

    Wolfgang A. Schulz

  • Epigenetics of prostate cancer: beyond DNA methylation.

    W A Schulz;J Hatina

  • Fibroblast Growth Factors and Their Receptors in Urological Cancers: Basic Research and Clinical Implications

    M.V Cronauer;W.A Schulz;H.-H Seifert;R Ackermann

  • DNA Methylation Signatures for Prediction of Biochemical Recurrence After Radical Prostatectomy of Clinically Localized Prostate Cancer

    Christa Haldrup;Kamilla Mundbjerg;Else Marie Vestergaard;Philippe Lamy

  • DKC1 overexpression associated with prostate cancer progression

    P Sieron;C Hader;J Hatina;R Engers

  • Downregulation of several fibulin genes in prostate cancer.

    Agnes Wlazlinski;Rainer Engers;Michèle J. Hoffmann;Christiane Hader

  • L1 Retrotransposons in Human Cancers

    Wolfgang A. Schulz

  • Glutathione transferase isozyme genotypes in patients with prostate and bladder carcinoma.

    Christine Steinhoff;Knut H. Franke;Klaus Golka;Ricarda Thier

  • Epigenetic control of CTCFL/BORIS and OCT4 expression in urogenital malignancies.

    Michèle J. Hoffmann;Mirko Müller;Rainer Engers;Wolfgang A. Schulz

  • The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

    Julie Earl;Daniel Rico;Enrique Carrillo-de-Santa-Pau;Benjamín Rodríguez-Santiago

Frequent Co-Authors

Helmut Sies
Helmut Sies Heinrich Heine University Düsseldorf
Peter J. Wild
Peter J. Wild Frankfurt Institute for Advanced Studies
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Tapio Visakorpi
Tapio Visakorpi Tampere University
Victoria Kolb-Bachofen
Victoria Kolb-Bachofen Heinrich Heine University Düsseldorf
Francisco X. Real
Francisco X. Real Pompeu Fabra University
Torben F. Ørntoft
Torben F. Ørntoft Aarhus University
Dieter Niederacher
Dieter Niederacher Heinrich Heine University Düsseldorf
Matthias U. Kassack
Matthias U. Kassack Heinrich Heine University Düsseldorf

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