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Frederic J. Seidler

Frederic J. Seidler

D-Index & Metrics

Medicine

D-Index
101
Citations
27186
World Ranking
8078
National Ranking
4195

Overview

Frederic J. Seidler is affiliated with Duke University in the United States and has contributed to research primarily within the field of Environmental Science. Their scholarly work focuses on Health, Toxicology and Mutagenesis, with additional involvement in Plant Science, Cell Biology, Pharmacology, and Pediatrics, Perinatology, and Child Health.

Their work addresses various topics including Environmental Toxicology and Ecotoxicology, Pesticide Exposure and Toxicity, Zebrafish Biomedical Research Applications, Cannabis and Cannabinoid Research, Prenatal Substance Exposure Effects, Neurotransmitter Receptor Influence on Behavior, and Neuroscience of respiration and sleep.

Frederic J. Seidler has published multiple research articles, with recent papers covering the following:

  • Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish (2020) in Neurotoxicology and Teratology
  • Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring (2020) in Toxicological Sciences
  • Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? (2021) in Neurotoxicology and Teratology
  • Paternal Cannabis Exposure Prior to Mating, but Not Δ9-Tetrahydrocannabinol, Elicits Deficits in Dopaminergic Synaptic Activity in the Offspring (2021) in Toxicological Sciences
  • Persistent neurobehavioral and neurochemical anomalies in middle-aged rats after maternal diazinon exposure (2022) in Toxicology

Their frequent collaborators include Theodore A. Slotkin, Edward D. Levin, Andrew B. Hawkey, Cassandra Dean, and Zade Holloway.

Frederic J. Seidler has published predominantly in the following venues:

  • Neurotoxicology and Teratology
  • Toxicological Sciences
  • Toxicology
  • Birth Defects Research
  • UNC Libraries

Best Publications

  • Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.

    Laura V. Dishaw;Christina M. Powers;Ian T. Ryde;Simon C. Roberts

  • Developmental neurotoxicity of chlorpyrifos: cellular mechanisms.

    Karl Whitney;F. J. Seidler;T. A. Slotkin

  • Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions

    J.A Trauth;F.J Seidler;E.C McCook;T.A Slotkin

  • Comparative Developmental Neurotoxicity of Organophosphates In Vivo: Transcriptional Responses of Pathways for Brain Cell Development, Cell Signaling, Cytotoxicity and Neurotransmitter Systems

    Theodore A. Slotkin;Frederic J. Seidler

  • Cellular Mechanisms for Developmental Toxicity of Chlorpyrifos: Targeting the Adenylyl Cyclase Signaling Cascade☆

    X. Song;F.J. Seidler;J.L. Saleh;J. Zhang

  • Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats.

    Edward D Levin;Nii Addy;Aya Nakajima;N.Channelle Christopher

  • Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.

    Hernan Navarro;FJ Seidler;JP Eylers;FE Baker

  • Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro

    Theodore A. Slotkin;Emiko A. MacKillop;Ronald L. Melnick;Kristina A. Thayer

  • Adrenomedullary function in the neonatal rat: responses to acute hypoxia.

    F J Seidler;T A Slotkin

  • Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression.

    Justin E. Aldridge;Edward D. Levin;Frederic J. Seidler;Theodore A. Slotkin

  • Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations.

    Edward D Levin;Nii Addy;Avanti Baruah;Alana Elias

  • Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity.

    K. Dam;F.J. Seidler;T.A. Slotkin

  • Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: Implications for sudden infant death syndrome

    T.A. Slotkin;S.E. Lappi;E.C. McCook;B.A. Lorber

  • Fetal and adolescent nicotine administration: effects on CNS serotonergic systems

    Z Xu;F.J Seidler;S.F Ali;S.F Ali;W Slikker;W Slikker

  • Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells.

    Dan Qiao;Frederic J. Seidler;Theodore A. Slotkin

  • Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways

    Kristina Dam;Stephanie J Garcia;Frederic J Seidler;Theodore A Slotkin

  • Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps.

    T A Slotkin;L Orband-Miller;K L Queen;W L Whitmore

  • Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation.

    T.L Crumpton;F.J Seidler;T.A Slotkin

  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells.

    X. Song;J.D. Violin;F.J. Seidler;T.A. Slotkin

  • Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition.

    Christina M. Powers;Appala R. Badireddy;Ian T. Ryde;Frederic J. Seidler

Frequent Co-Authors

Theodore A. Slotkin
Theodore A. Slotkin Duke University
Edward D. Levin
Edward D. Levin Duke University
Joseph Yanai
Joseph Yanai Hebrew University of Jerusalem
Garth Bissette
Garth Bissette Duke University
Kent E. Pinkerton
Kent E. Pinkerton University of California, Davis
Charles B. Nemeroff
Charles B. Nemeroff The University of Texas at Austin
Heather M. Stapleton
Heather M. Stapleton Duke University
Syed F. Ali
Syed F. Ali National Center for Toxicological Research
Kyle R. Gee
Kyle R. Gee Thermo Fisher Scientific (Norway)
Andrew W. Zimmerman
Andrew W. Zimmerman University of Massachusetts Chan Medical School

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