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Genetics

D-Index
62
Citations
21633
World Ranking
2947
National Ranking
1289

Overview

Victor V. Lobanenkov is affiliated with the National Institutes of Health in the United States, focusing primarily on the field of Biochemistry, Genetics, and Molecular Biology. Their research covers a broad range of subfields including Molecular Biology, Genetics, Surgery, Cancer Research, and Plant Science.

The primary topics of their work include:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • Testicular diseases and treatments
  • Sexual Differentiation and Disorders
  • Cancer Genomics and Diagnostics

Lobanenkov has contributed to several peer-reviewed publications in highly regarded venues. Notable frequent publication platforms include:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Molecular Neuroscience
  • Genome Biology

Their recent papers demonstrate a focus on chromatin structure, gene regulation, and the molecular mechanisms underlying spermatogenesis and chromosome stability. Key publications include:

  • "CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention," 2020, Proceedings of the National Academy of Sciences
  • "The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis," 2021, Nature Communications
  • "Ectopic expression of meiotic cohesin generates chromosome instability in cancer cell line," 2022, Proceedings of the National Academy of Sciences
  • "An updated catalog of CTCF variants associated with neurodevelopmental disorder phenotypes," 2023, Frontiers in Molecular Neuroscience
  • "BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites," 2024, Genome Biology

Their research collaborations include frequent partnerships with several co-authors who have contributed extensively alongside them. These frequent collaborators are:

  • Elena M. Pugacheva
  • Dmitri Loukinov
  • Alexander Strunnikov
  • Md Tajmul
  • Samuel Rivero-Hinojosa

Lobanenkov's work encompasses a blend of fundamental molecular biology and applied biomedical research, addressing mechanisms of chromatin organization, epigenetic regulation, and their implications for reproductive biology and cancer. Their contributions span over two decades and cover a comprehensive range of molecular genetic topics and emerging biomedical issues.

Best Publications

  • Histone Modifications at Human Enhancers Reflect Global Cell-Type-Specific Gene Expression

    Nathaniel D. Heintzman;Gary C. Hon;R. David Hawkins;Pouya Kheradpour

  • Chromatin architecture reorganization during stem cell differentiation

    Jesse R. Dixon;Inkyung Jung;Siddarth Selvaraj;Yin Shen

  • A map of the cis-regulatory sequences in the mouse genome

    Yin Shen;Feng Yue;David F. McCleary;Zhen Ye

  • Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome

    Tae Hoon Kim;Ziedulla K. Abdullaev;Andrew D. Smith;Keith A. Ching

  • An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.

    G N Filippova;S Fagerlie;E M Klenova;C Myers

  • CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

    Rolf Ohlsson;Rainer Renkawitz;Victor Lobanenkov

  • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

    Sreenivasulu Kurukuti;Vijay Kumar Tiwari;Gholamreza Tavoosidana;Elena Pugacheva

  • Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

    Chandrasekhar Kanduri;Vinod Pant;Dmitri Loukinov;Elena Pugacheva

  • BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

    Dmitri I. Loukinov;Elena Pugacheva;Sergei Vatolin;Svetlana D. Pack

  • A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene.

    V V Lobanenkov;R H Nicolas;V V Adler;H Paterson

  • CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus

    Galina N. Filippova;Cortlandt P. Thienes;Bennett H. Penn;Diane H. Cho

  • The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer.

    Elena M Klenova;Herbert C Morse;Rolf Ohlsson;Victor V Lobanenkov

  • A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code

    Hirotaka Nakahashi;Kyong Rim Kieffer Kwon;Wolfgang Resch;Laura Vian

  • CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms.

    E M Klenova;R H Nicolas;H F Paterson;A F Carne

  • Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation

    Wenqiang Yu;Vasudeva Ginjala;Vinod Pant;Igor Chernukhin

  • CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator

    Hanlim Moon;Galina Filippova;Dmitry Loukinov;Elena Pugacheva

  • Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

    S. Renaud;D. Loukinov;Z. Abdullaev;I. Guilleret

  • Conditional Expression of the CTCF-Paralogous Transcriptional Factor BORIS in Normal Cells Results in Demethylation and Derepression of MAGE-A1 and Reactivation of Other Cancer-Testis Genes

    Sergei Vatolin;Ziedulla Abdullaev;Svetlana D. Pack;Patrick T. Flanagan

  • The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains

    Vinod Pant;Piero Mariano;Chandrasekhar Kanduri;Anita Mattsson

  • Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells.

    Julie A. Hong;Yang Kang;Ziedulla Abdullaev;Patrick T. Flanagan

Frequent Co-Authors

Rolf Ohlsson
Rolf Ohlsson Karolinska Institute
Svetlana Pack
Svetlana Pack National Institutes of Health
Herbert C. Morse
Herbert C. Morse National Institute of Allergy and Infectious Diseases
Bing Ren
Bing Ren New York Genome Center
Graham H. Goodwin
Graham H. Goodwin Institute of Cancer Research
Paul E. Neiman
Paul E. Neiman Fred Hutchinson Cancer Research Center
Rainer Renkawitz
Rainer Renkawitz University of Giessen
John E.J. Rasko
John E.J. Rasko Centenary Institute of Cancer Medicine and Cell Biology
Steven J. Collins
Steven J. Collins University of Melbourne
Andrew P. Feinberg
Andrew P. Feinberg Johns Hopkins University

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