D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 84 Citations 25,046 201 World Ranking 555 National Ranking 276

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Internal medicine
  • Biochemistry

Charles G. Cochrane mostly deals with Biochemistry, Immunology, Antibody, Molecular biology and Antigen. His Biochemistry study frequently links to other fields, such as Factor XII. His Immunology research incorporates elements of Acetylcholine receptor, Postsynaptic potential and Neuromuscular transmission.

His Antibody research incorporates elements of Glomerulonephritis, Immune system and Globulin. His work deals with themes such as DNA damage, Platelet-activating factor receptor, Conserved sequence, cDNA library and Nicotinamide adenine dinucleotide, which intersect with Molecular biology. The concepts of his Antigen study are interwoven with issues in Vasculitis and Guinea pig.

His most cited work include:

  • LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS THE ROLE OF IGE, BASOPHILS, AND A PLATELET-ACTIVATING FACTOR (1059 citations)
  • Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide. (549 citations)
  • Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. (482 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Biochemistry, Immunology, Molecular biology, Antibody and Pulmonary surfactant. His research ties Factor XII and Biochemistry together. In Immunology, Charles G. Cochrane works on issues like Bronchoalveolar lavage, which are connected to ARDS.

His Molecular biology research integrates issues from In vitro and DNA damage. His studies in Antibody integrate themes in fields like Guinea pig, Immune system, Antigen and Pathology. His work in Pulmonary surfactant covers topics such as Respiratory distress which are related to areas like Lung.

He most often published in these fields:

  • Biochemistry (36.26%)
  • Immunology (29.77%)
  • Molecular biology (20.61%)

What were the highlights of his more recent work (between 1989-2017)?

  • Biochemistry (36.26%)
  • Pulmonary surfactant (12.98%)
  • Receptor (10.69%)

In recent papers he was focusing on the following fields of study:

Charles G. Cochrane mainly focuses on Biochemistry, Pulmonary surfactant, Receptor, Cell biology and Molecular biology. His Biochemistry study often links to related topics such as Transfection. He has researched Pulmonary surfactant in several fields, including Amino acid residue, Phospholipid, Respiratory distress and Sequence.

His Molecular biology research incorporates themes from cDNA library and Interleukin 8. Interleukin 8 is a subfield of Immunology that Charles G. Cochrane tackles. His Immunology study combines topics in areas such as Kininogen, Function and Histamine.

Between 1989 and 2017, his most popular works were:

  • Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation (293 citations)
  • Pulmonary surfactant protein B (SP-B): structure-function relationships. (272 citations)
  • Cellular injury by oxidants (235 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Internal medicine
  • Biochemistry

Charles G. Cochrane mainly investigates Receptor, Biochemistry, Anesthesia, Molecular biology and Bronchoalveolar lavage. His Receptor study incorporates themes from In vitro and Cell biology. His research in NAD+ kinase, DNA, Oxidative phosphorylation, DNA damage and Glyceraldehyde 3-phosphate dehydrogenase are components of Biochemistry.

His research integrates issues of Inflammation, Interleukin, Interleukin 8, Cytokine and Lipopolysaccharide in his study of Molecular biology. His studies deal with areas such as ARDS and Surgery as well as Bronchoalveolar lavage. Charles G. Cochrane has included themes like Neutrophil elastase, Elastase, Pulmonary Injury and Immunology in his ARDS study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS THE ROLE OF IGE, BASOPHILS, AND A PLATELET-ACTIVATING FACTOR

Jacques Benveniste;Peter M. Henson;Charles G. Cochrane.
Journal of Experimental Medicine (1972)

1710 Citations

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

P A Hyslop;D B Hinshaw;W A Halsey;I U Schraufstätter.
Journal of Biological Chemistry (1988)

868 Citations

Immune Complex Disease in Experimental Animals and Man

C G Cochrane;D Koffler.
Advances in Immunology (1973)

759 Citations

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

I U Schraufstatter;D B Hinshaw;P A Hyslop;R G Spragg.
Journal of Clinical Investigation (1986)

747 Citations

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

Ingrid U. Schraufstatter;Paul A. Hyslop;Daniel B. Hinshaw;Roger G. Spragg.
Proceedings of the National Academy of Sciences of the United States of America (1986)

669 Citations

Depletion of Plasma Complement in Vivo by a Protein of Cobra Venom: Its Effect on Various Immunologic Reactions

Charles G. Cochrane;Hans J. Müller-Eberhard;Barbara S. Aikin.
Journal of Immunology (1970)

610 Citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

Charles A. Parkos;Rodger A. Allen;Charles G. Cochrane;Algirdas J. Jesaitis.
Journal of Clinical Investigation (1987)

605 Citations

THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT

C. G. Cochrane;H. J. Müller-Eberhard.
Journal of Experimental Medicine (1968)

597 Citations

Isolation of a fragment (C3a) of the third component of human complement containing anaphylatoxin and chemotactic activity and description of an anaphylatoxin inactivator of human serum.

Viktor A. Bokisch;Hans J. Müller-Eberhard;Charles G. Cochrane.
Journal of Experimental Medicine (1969)

560 Citations

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS.

Charles G. Cochrane;Emil R. Unanue;Frank J. Dixon.
Journal of Experimental Medicine (1965)

550 Citations

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