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Microbiology

D-Index
88
Citations
28567
World Ranking
758
National Ranking
354

Overview

Charles G. Cochrane is affiliated with the Scripps Research Institute in the United States. Their research primarily centers on the field of Immunology and Microbiology, with a specific focus on Immunology as a subfield.

The scientist's work addresses topics related to neutrophils, myeloperoxidase, and oxidative mechanisms. These themes have been highlighted across multiple publications, indicating a sustained interest in cellular oxidative processes and immune cell function.

Their publication record includes research such as the paper titled "Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA", published in 2020 in UNC Libraries. This work addresses mechanisms of superoxide generation in chronic granulomatous disease, reflecting a molecular and cellular approach within immunological research.

Frequent collaborators in their research include:

  • Friedrich E. Maly
  • Cornelia C. Schuerer-Maly
  • Lawrence A. Quilliam
  • Peter E. Newburger
  • John T. Curnutte

Their publications have appeared in venues such as:

  • UNC Libraries

The topics they study demonstrate a focus on the biochemical and cellular aspects of immune function, particularly relating to oxidative responses in immune cells. Their work contributes to an understanding of immune deficiencies and the molecular basis of related disorders.

Best Publications

  • LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS THE ROLE OF IGE, BASOPHILS, AND A PLATELET-ACTIVATING FACTOR

    Jacques Benveniste;Peter M. Henson;Charles G. Cochrane

  • Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

    P A Hyslop;D B Hinshaw;W A Halsey;I U Schraufstätter

  • Immune Complex Disease in Experimental Animals and Man

    C G Cochrane;D Koffler

  • Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

    I U Schraufstatter;D B Hinshaw;P A Hyslop;R G Spragg

  • Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

    Ingrid U. Schraufstatter;Paul A. Hyslop;Daniel B. Hinshaw;Roger G. Spragg

  • Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

    Charles A. Parkos;Rodger A. Allen;Charles G. Cochrane;Algirdas J. Jesaitis

  • Depletion of Plasma Complement in Vivo by a Protein of Cobra Venom: Its Effect on Various Immunologic Reactions

    Charles G. Cochrane;Hans J. Müller-Eberhard;Barbara S. Aikin

  • THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT

    C. G. Cochrane;H. J. Müller-Eberhard

  • Isolation of a fragment (C3a) of the third component of human complement containing anaphylatoxin and chemotactic activity and description of an anaphylatoxin inactivator of human serum.

    Viktor A. Bokisch;Hans J. Müller-Eberhard;Charles G. Cochrane

  • A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS.

    Charles G. Cochrane;Emil R. Unanue;Frank J. Dixon

  • Oxidant-induced DNA damage of target cells.

    I Schraufstätter;P A Hyslop;J H Jackson;C G Cochrane

  • THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO

    P A Ward;C G Cochrane;H J Mueller-Eberhard

  • Studies on the Pathogenesis of the Adult Respiratory Distress Syndrome

    William W. Mcguire;Roger G. Spragg;Allen B. Cohen;Charles G. Cochrane

  • ACTIVATION OF HAGEMAN FACTOR IN SOLID AND FLUID PHASES A CRITICAL ROLE OF KALLIKREIN

    C. G. Cochrane;S. D. Revak;K. D. Wuepper

  • Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid.

    C G Cochrane;R Spragg;S D Revak

  • Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

    Janis H. Jackson;Charles G. Cochrane;Jeffrey R. Bourne;Patricia A. Solski

  • Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia.

    T A Merritt;C G Cochrane;K Holcomb;B Bohl

  • Mechanisms for the involvement of high molecular weight kininogen in surface-dependent reactions of Hageman factor

    John H. Griffin;Charles G. Cochrane

  • Detection of Tissue Kallikrein in the Bronchoalveolar Lavage Fluid of Asthmatic Subjects

    S C Christiansen;D Proud;C G Cochrane

  • Cellular injury by oxidants

    Charles G. Cochrane

Frequent Co-Authors

Algirdas J. Jesaitis
Algirdas J. Jesaitis Montana State University
Larry A. Sklar
Larry A. Sklar University of New Mexico
Peter M. Henson
Peter M. Henson National Jewish Health
Richard J. Ulevitch
Richard J. Ulevitch Scripps Research Institute
John H. Griffin
John H. Griffin Scripps Research Institute
Richard D. Ye
Richard D. Ye Chinese University of Hong Kong, Shenzhen
Eric R. Prossnitz
Eric R. Prossnitz University of New Mexico
Oswald Quehenberger
Oswald Quehenberger University of California, San Diego
Mikko Hallman
Mikko Hallman Oulu University Hospital
Frank J. Dixon
Frank J. Dixon Scripps Health

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