Guido Tans

Overview

Best Publications

• The role of phospholipids and factor Va in the prothrombinase complex.

  J Rosing;G Tans;J W Govers-Riemslag;R F Zwaal

  809
  Citations

• The role of phospholipid and factor VIIIa in the activation of bovine factor X.

  G van Dieijen;G Tans;J Rosing;H C Hemker

  728
  Citations

• Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second- and third-generation oral contraceptives

  J. Rosing;G. Tans;G.A.F. Nicolaes;M.C.G.L.D. Thomassen

  456
  Citations

• Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles.

  G Tans;J Rosing;MC Thomassen;MJ Heeb

  388
  Citations

• Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor

  Tilman M. Hackeng;Kristin M. Seré;Guido Tans;Jan Rosing

  353
  Citations

• Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study.

  Jan Rosing;Saskia Middeldorp;Joyce Curvers;M Christella L GDlig

  335
  Citations

• Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C.

  Gerry A.F. Nicolaes;Guido Tans;M. Christella L.G.D. Thomassen;H. Coenraad Hemker

  306
  Citations

• Effects of Protein S and Factor Xa on Peptide Bond Cleavages during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

  Jan Rosing;Lico Hoekema;Gerry A.F. Nicolaes;M. Christella L. G. D. Thomassen

  303
  Citations

• Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.

  M J Heeb;R M Mesters;G Tans;J Rosing

  290
  Citations

• A Randomized Cross-over Study on the Effects of Levonorgestrel- and Desogestrel-containing Oral Contraceptives on the Anticoagulant Pathways

  G. Tans;J. Curvers;S. Middeldorp;M. C. L. G. D. Thomassen

  264
  Citations

• Effects on Coagulation of Levonorgestrel- and Desogestrel-containing Low Dose Oral Contraceptives: a Cross-over Study

  S. Middeldorp;J. C. M. Meijers;A. E. Van Den Ende;A. Van Enk

  261
  Citations

• Venous Thrombosis and Changes of Hemostatic Variables during Cross-Sex Hormone Treatment in Transsexual People

  A. W. F. T. Toorians;M. C. L. G. D. Thomassen;S. Zweegman;E. J. P. Magdeleyns

  258
  Citations

• Protein S binds to and inhibits factor Xa

  Mary J. Heeb;Jan Rosing;Harry M. Bakker;Jose A. Fernandez

  226
  Citations

• Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial.

  Jeanet M. Kemmeren;Ale Algra;Joost C. M. Meijers;Guido Tans

  191
  Citations

• Increased fibrinolytic activity during use of oral contraceptives is counteracted by an enhanced factor XI-independent down regulation of fibrinolysis: a randomized cross-over study of two low-dose oral contraceptives.

  J. C. M. Meijers;S. Middeldorp;W. Tekelenburg;A. E. Van Den Ende

  190
  Citations

• Activated protein C resistance determined with a thrombin generation‐based test predicts for venous thrombosis in men and women

  Guido Tans;Astrid Van Hylckama Vlieg;M. Christella L. G. D. Thomassen;Joyce Curvers

  178
  Citations

• Sulfatide-dependent autoactivation of human blood coagulation Factor XII (Hageman Factor).

  G Tans;J Rosing;J H Griffin

  174
  Citations

• Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

  Joke Konings;José W P Govers-Riemslag;Helen Philippou;Nicola J Mutch

  164
  Citations

• Formation of meizothrombin as intermediate in factor Xa-catalyzed prothrombin activation.

  J Rosing;R F Zwaal;G Tans

  157
  Citations

• Factor V enhances the cofactor function of protein S in the APC-mediated inactivation of factor VIII: influence of the factor VR506Q mutation.

  K Váradi;J Rosing;G Tans;I Pabinger

  153
  Citations