Paul Comfurius

Overview

Best Publications

• Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

  M. Galli;T. Barbui;P. Comfurius;C. Maassen

  1748
  Citations

• The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy

  A.J Verkleij;R.F.A Zwaal;B Roelofsen;P Comfurius

  1545
  Citations

• Surface exposure of phosphatidylserine in pathological cells.

  R. F. A. Zwaal;P. Comfurius;E. M. Bevers

  990
  Citations

• Changes in membrane phospholipid distribution during platelet activation

  Edouard M. Bevers;Paul Comfurius;Robert F.A. Zwaal

  804
  Citations

• Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin

  E M Bevers;M Galli;T Barbui;P Comfurius

  766
  Citations

• Generation of prothrombin-converting activity and the exposure of phosphatidylserine at the outer surface of platelets.

  Edouard M. Bevers;Paul Comfurius;Jan L.M.L. van Rijn;H. Coenraad Hemker

  634
  Citations

• Lipid translocation across the plasma membrane of mammalian cells

  Edouard M Bevers;Paul Comfurius;David W.C Dekkers;Robert F.A Zwaal

  620
  Citations

• Organization of phospholipids in human red cell membranes as detected by the action of various purified phospholipases.

  R.F.A. Zwaal;B. Roelofsen;P. Comfurius;L.L.M. van Deenen

  525
  Citations

• Lipid-protein interactions in blood coagulation.

  Robert F.A Zwaal;Paul Comfurius;Edouard M Bevers

  427
  Citations

• Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase.

  Paul Comfurius;Joan M.G. Senden;Roland H.J. Tilly;Alan J. Schroit

  412
  Citations

• The role of activated human platelets in prothrombin and factor X activation.

  J Rosing;JL van Rijn;EM Bevers;G van Dieijen

  337
  Citations

• Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids.

  Robert F.A Zwaal;Paul Comfurius;Edouard M Bevers

  303
  Citations

• Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes.

  George M. Willems;Marie P. Janssen;Maurice M. A. L. Pelsers;Paul Comfurius

  276
  Citations

• Complete purification and some properties of phospholipase C from Bacillus cereus

  R.F.A. Zwaal;B. Roelofsen;P. Comfurius;L.L.M. Van Deenen

  263
  Citations

• Uncoupling of the membrane skeleton from the lipid bilayer. The cause of accelerated phospholipid flip-flop leading to an enhanced procoagulant activity of sickled cells.

  P F Franck;E M Bevers;B H Lubin;P Comfurius

  252
  Citations

• Anticoagulant activity of beta 2-glycoprotein I is potentiated by a distinct subgroup of anticardiolipin antibodies.

  Monica Galli;Paul Comfurius;Tiziano Barbui;Robert F A Zwaal

  247
  Citations

• Continuous analysis of the mechanism of activated transbilayer lipid movement in platelets.

  Patrick Williamson;Edouard M. Bevers;Edgar F. Smeets;Paul Comfurius

  247
  Citations

• Platelet procoagulant activity: physiological significance and mechanisms of exposure

  E.M. Bevers;P. Comfurius;R.F.A. Zwaal

  240
  Citations

• Platelet procoagulant activity and microvesicle formation. Its putative role in hemostasis and thrombosis

  Robert F.A. Zwaal;Paul Comfurius;Edouard M. Bevers

  231
  Citations

• Defective Ca(2+)-induced microvesiculation and deficient expression of procoagulant activity in erythrocytes from a patient with a bleeding disorder: a study of the red blood cells of Scott syndrome

  Edouard M. Bevers;Therese Wiedmer;Paul Comfurius;Sanford J. Shattil

  207
  Citations