John B. Imboden mostly deals with T cell, Molecular biology, Jurkat cells, Cell biology and Biochemistry. His studies in T cell integrate themes in fields like Cell surface receptor and Intracellular. His studies deal with areas such as Antigen, Signal transduction, Tyrosine phosphorylation, CD28 and SH3 domain as well as Molecular biology.
His Jurkat cells research integrates issues from Interleukin 2 and Inositol trisphosphate receptor. His Cell biology study frequently links to other fields, such as Lymphokine. His Biochemistry study frequently draws connections to adjacent fields such as T lymphocyte.
John B. Imboden focuses on Rheumatoid arthritis, Cell biology, T cell, Molecular biology and Jurkat cells. His work deals with themes such as Wrist, Radiology and Nuclear medicine, which intersect with Rheumatoid arthritis. His Cell biology research incorporates themes from Natural killer T cell, Biochemistry and Lymphokine-activated killer cell.
His T cell study combines topics from a wide range of disciplines, such as Cell surface receptor and Lymphokine, Antigen. The various areas that John B. Imboden examines in his Molecular biology study include Cytoplasm and Interleukin 2, Receptor, Signal transduction, Tyrosine phosphorylation. In his research, Inositol phosphate is intimately related to Receptor complex, which falls under the overarching field of Jurkat cells.
His primary areas of investigation include Rheumatoid arthritis, Quantitative computed tomography, Wrist, Internal medicine and Radiology. John B. Imboden interconnects Methotrexate, Radiography, Arthritis, Nuclear medicine and Magnetic resonance imaging in the investigation of issues within Rheumatoid arthritis. The concepts of his Radiography study are interwoven with issues in Erythrocyte sedimentation rate, Coefficient of variation and Urology.
The Wrist study which covers Tumor necrosis factor alpha that intersects with Baseline time, Joint destruction and Wrist joints. His work carried out in the field of Internal medicine brings together such families of science as Gastroenterology and Physical therapy. His study in the field of 3 Tesla Magnetic Resonance Imaging and Conventional radiographs is also linked to topics like Correlation.
John B. Imboden mainly investigates Rheumatoid arthritis, Quantitative computed tomography, Wrist, Internal medicine and Peripheral. John B. Imboden integrates Rheumatoid arthritis and Decision-making in his research. His Quantitative computed tomography research includes elements of Radiology, Nuclear medicine and Magnetic resonance imaging.
In general Radiology, his work in Radiography is often linked to Metacarpophalangeal joint and In vivo linking many areas of study. His work on Rheumatology, Retrospective cohort study and Endothelial dysfunction as part of general Internal medicine research is frequently linked to Reactive hyperemia, thereby connecting diverse disciplines of science. His Rheumatology research includes themes of Arthritis, Physical therapy and Intensive care medicine.
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Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.
J B Imboden;J D Stobo.
Journal of Experimental Medicine (1985)
The Role of the T3/Antigen Receptor Complex in T-Cell Activation
Arthur Weiss;John Imboden;Kenneth Hardy;Bernhard Manger.
Annual Review of Immunology (1986)
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium
Arthur Weiss;John Imboden;Dolores Shoback;John Stobo.
Proceedings of the National Academy of Sciences of the United States of America (1984)
Cell surface molecules and early events involved in human T lymphocyte activation.
Arthur Weiss;John B. Imboden.
Advances in Immunology (1987)
The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium.
J B Imboden;A Weiss;J D Stobo.
Journal of Immunology (1985)
Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphosphate and cytoplasmic free calcium.
John B. Imboden;Dolores M. Shoback;Gregory Pattison;John D. Stobo.
Proceedings of the National Academy of Sciences of the United States of America (1986)
The Immunopathogenesis of Rheumatoid Arthritis
John B. Imboden.
Annual Review of Pathology-mechanisms of Disease (2009)
CD28 Mediates Transcriptional Upregulation of the Interleukin-2 (IL-2) Promoter through a Composite Element Containing the CD28RE and NF-IL-2B AP-1 Sites
Virginia Smith Shapiro;Kenneth E. Truitt;John B. Imboden;Arthur Weiss.
Molecular and Cellular Biology (1997)
CD28 ligation in T-cell activation: evidence for two signal transduction pathways.
Jeffrey A. Ledbetter;John B. Imboden;Gary L. Schieven;Laura S. Grosmaire.
Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells.
K E Truitt;C M Hicks;J B Imboden.
Journal of Experimental Medicine (1994)
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