Juan J. Lafaille

Overview

Best Publications

• The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

  Ivaylo I. Ivanov;Brent S. McKenzie;Liang Zhou;Carlos E. Tadokoro

  6624
  Citations

• Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

  Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas

  2798
  Citations

• Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

  Maria A. Curotto de Lafaille;Juan J. Lafaille

  1517
  Citations

• Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

  Peter Mombaerts;Alan R. Clarke;Michael A. Rudnicki;John Iacomini

  1339
  Citations

• Interleukin 2 signaling is required for CD4(+) regulatory T cell function.

  Gláucia C. Furtado;Maria A. Curotto de Lafaille;Nino Kutchukhidze;Juan J. Lafaille

  925
  Citations

• Correction: Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers

  Leigh Jones;Wen Qi Ho;Sze Ying;Lakshmi Ramakrishna

  845
  Citations

• High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

  Juan J. Lafaille;Kumiko Nagashima;Motoya Katsuki;Susumu Tonegawa

  787
  Citations

• Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

  Juan J. Lafaille;Amy DeCloux;Marc Bonneville;Yohtaroh Takagaki

  762
  Citations

• Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

  Angelina M. Bilate;Juan J. Lafaille

  755
  Citations

• Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

  Jonathan M. Weiss;Angelina M. Bilate;Michael Gobert;Yi Ding

  735
  Citations

• Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

  Carlos E. Tadokoro;Guy Shakhar;Shiqian Shen;Yi Ding

  684
  Citations

• Oral tolerance in the absence of naturally occurring Tregs

  Daniel Mucida;Nino Kutchukhidze;Agustin Erazo;Momtchilo Russo

  635
  Citations

• Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

  Juan J. Lafaille;Fabienne Van de Keere;Albert L. Hsu;Jody L. Baron

  628
  Citations

• Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

  Shigeyoshi Itohara;Shigeyoshi Itohara;Shigeyoshi Itohara;Andrew G. Farr;Andrew G. Farr;Andrew G. Farr;Juan J. Lafaille;Juan J. Lafaille;Juan J. Lafaille;Marc Bonneville;Marc Bonneville;Marc Bonneville

  624
  Citations

• T cell receptor δ gene mutant mice : independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

  Shigeyoshi Itohara;Peter Mombaerts;Juan Lafaille;John Iacomini

  618
  Citations

• Digoxin and its derivatives suppress Th17 cell differentiation by antagonizing RORγt activity

  Jun R. Huh;Monica W. L. Leung;Pengxiang Huang;Daniel A. Ryan

  613
  Citations

• Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

  Yi Yang;Miriam B. Torchinsky;Michael Gobert;Huizhong Xiong

  582
  Citations

• CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

  Maria A. Curotto de Lafaille;Andreia C. Lino;Nino Kutchukhidze;Juan J. Lafaille

  537
  Citations

• Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation.

  Maria A. Curotto de Lafaille;Nino Kutchukhidze;Shiqian Shen;Yi Ding

  522
  Citations

• Regulatory CD4+ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis

  Danyvid Olivares-Villagómez;Yijie Wang;Juan J. Lafaille

  439
  Citations

• CD4(+) regulatory T cells in autoimmunity and allergy.

  Maria A Curotto de Lafaille;Juan J Lafaille

  332
  Citations

• Protein kinase C-θ mediates negative feedback on regulatory T cell function

  Alexandra Zanin-Zhorov;Yi Ding;Sudha Kumari;Mukundan Attur

  321
  Citations

• Sequential class switching is required for the generation of high affinity IgE antibodies

  Huizhong Xiong;Jayashree Dolpady;Matthias Wabl;Maria A. Curotto de Lafaille

  278
  Citations