His scientific interests lie mostly in Immunology, IL-2 receptor, FOXP3, Cell biology and Immune tolerance. In most of his Immunology studies, his work intersects topics such as Cellular differentiation. His research in FOXP3 tackles topics such as Inflammation which are related to areas like Immune system and Regulation of gene expression.
His Cell biology study often links to related topics such as Cytotoxic T cell. His work focuses on many connections between Immune tolerance and other disciplines, such as Allergic inflammation, that overlap with his field of interest in Homeostasis. Juan J. Lafaille interconnects Proinflammatory cytokine, T helper 17 cell and Cytokine in the investigation of issues within RAR-related orphan receptor gamma.
Immunology, Cell biology, IL-2 receptor, Antigen and T-cell receptor are his primary areas of study. Immunology is frequently linked to Cytotoxic T cell in his study. The concepts of his Cell biology study are interwoven with issues in Regulatory T cell, Proinflammatory cytokine and Cytokine.
Many of his studies involve connections with topics such as Interleukin 21 and IL-2 receptor. His Antigen research is multidisciplinary, incorporating elements of Flow cytometry, Immunoglobulin E and Germinal center. His T-cell receptor research also works with subjects such as
Juan J. Lafaille mainly investigates Immunology, Cell biology, Antigen, Germinal center and Antigen presentation. His Spleen, Immunoglobulin E, Inflammation, Colitis and Memory B cell study are his primary interests in Immunology. In the field of Cell biology, his study on Homeostasis overlaps with subjects such as Chemistry.
As a part of the same scientific study, Juan J. Lafaille usually deals with the Antigen, concentrating on Immune system and frequently concerns with Cytotoxic T cell and Secondary infection. His Germinal center study which covers Green fluorescent protein that intersects with B cell, BCL6 and Cytokine. Juan J. Lafaille usually deals with Antigen presentation and limits it to topics linked to FOXP3 and T cell.
The scientist’s investigation covers issues in Immunology, Germinal center, CD80, Immunoglobulin E and Memory B cell. His study brings together the fields of Cell type and Immunology. His work carried out in the field of Cell type brings together such families of science as T cell, Immune system, Transcription factor and Antigen.
His CD80 research is multidisciplinary, relying on both Plasma cell, Immunoglobulin class switching, Immunoglobulin G, Somatic hypermutation and CD23. His Innate immune system research incorporates themes from Neuroimmunology, Central nervous system, Inflammation and Motor learning. Juan J. Lafaille combines subjects such as Tumor necrosis factor alpha and Postsynaptic potential with his study of Motor learning.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.
Ivaylo I. Ivanov;Brent S. McKenzie;Liang Zhou;Carlos E. Tadokoro.
Cell (2006)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas.
Cell (2013)
Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?
Maria A. Curotto de Lafaille;Juan J. Lafaille.
Immunity (2009)
Interleukin 2 signaling is required for CD4(+) regulatory T cell function.
Gláucia C. Furtado;Maria A. Curotto de Lafaille;Nino Kutchukhidze;Juan J. Lafaille.
Journal of Experimental Medicine (2002)
Correction: Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers
Leigh Jones;Wen Qi Ho;Sze Ying;Lakshmi Ramakrishna.
Scientific Reports (2016)
Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance
Angelina M. Bilate;Juan J. Lafaille.
Annual Review of Immunology (2012)
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
Jonathan M. Weiss;Angelina M. Bilate;Michael Gobert;Yi Ding.
Journal of Experimental Medicine (2012)
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
Carlos E. Tadokoro;Guy Shakhar;Shiqian Shen;Yi Ding.
Journal of Experimental Medicine (2006)
Oral tolerance in the absence of naturally occurring Tregs
Daniel Mucida;Nino Kutchukhidze;Agustin Erazo;Momtchilo Russo.
Journal of Clinical Investigation (2005)
Digoxin and its derivatives suppress Th17 cell differentiation by antagonizing RORγt activity
Jun R. Huh;Monica W. L. Leung;Pengxiang Huang;Daniel A. Ryan.
Nature (2011)
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