World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
71
Citations
22046
World Ranking
1814
National Ranking
774

Medicine

D-Index
76
Citations
26577
World Ranking
18663
National Ranking
9299

Overview

Leon G. Epstein is affiliated with Northwestern University in the United States and has contributed extensively to the field of medicine, focusing on various subfields including general health professions, public health, environmental and occupational health, pediatrics, perinatology and child health, molecular biology, and economics and econometrics.

Their research encompasses several main topics, including ethics and legal issues in pediatric healthcare, ethics in medical practice, palliative care and end-of-life issues, health systems, economic evaluations, quality of life, disaster response and management, organ donation and transplantation, and patient dignity and privacy.

Leon G. Epstein has published in a range of academic venues, with frequent publications in:

  • Annals of Clinical and Translational Neurology
  • Neurology
  • Brain
  • Developmental Medicine & Child Neurology
  • Pediatric Neurology

The scientist's recent papers include:

  • Updated research nosology for HIV-associated neurocognitive disorders, 2020, UNC Libraries
  • Clinical Guidance in Neuropalliative Care, 2022, Neurology
  • Ethical Considerations in Dementia Diagnosis and Care, 2021, Neurology
  • Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes, 2024, Nature Neuroscience
  • Use of Social Media in Health Care-Opportunities, Challenges, and Ethical Considerations, 2021, Neurology

Collaborative work is a significant aspect of Epstein's research activities. Frequent co-authors include:

  • John A. Kessler
  • Jennifer Graves
  • Ahmet Höke
  • Johns Hopkins
  • Puneet Opal

Best Publications

  • Updated research nosology for HIV-associated neurocognitive disorders

    A. Antinori;G. Arendt;J. T. Becker;B. J. Brew

  • Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

    Richard S. Finkel;Eugenio Mercuri;Basil T. Darras;Anne M. Connolly

  • HTLV-III infection in brains of children and adults with AIDS encephalopathy

    George M. Shaw;Mary E. Harper;Beatrice H. Hahn;Leon G. Epstein

  • Human Herpesvirus-6 Infection in Children -- A Prospective Study of Complications and Reactivation

    Caroline Breese Hall;Christine E. Long;Kenneth C. Schnabel;Mary T. Caserta

  • Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection.

    Jaap Goudsmit;DeborahA. Paul;JoepM.A. Lange;Hans Speelman

  • HIV-associated cognitive impairment before and after the advent of combination therapy

    Ned Sacktor;Ned Sacktor;Michael P. McDermott;Karen Marder;Giovanni Schifitto

  • Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection

    Robert S. Janssen;David R. Cornblath;Leon G. Epstein;Richard P. Foa

  • Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patients.

    D. Carleton Gajdusek;Clarence J. Gibbs;Pamela Rodgers-Johnson;Herbert L. Amyx

  • Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease.

    Peter Genis;Marti Jett;Edward W. Bernton;Thomas Boyle

  • Neurologic Manifestations of Human Immunodeficiency Virus Infection in Children

    L. G. Epstein;Leroy Sharer;James Oleske;E. M. Connor

  • Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms.

    Leon G. Epstein;Howard E. Gendelman

  • Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues

    Y. Saito;L. R. Sharer;L. G. Epstein;J. Michaels

  • Tumor Necrosis Factor α Inhibits Glutamate Uptake by Primary Human Astrocytes IMPLICATIONS FOR PATHOGENESIS OF HIV-1 DEMENTIA

    Steven M. Fine;Robert A. Angel;Seth W. Perry;Leon G. Epstein

  • HIV-associated disease of the nervous system: review of nomenclature and proposal for neuropathology-based terminology.

    Herbert Budka;Clayton A. Wiley;Paul Kleihues;Juan Artigas

  • Depressive Symptoms as Predictors of Medical Outcomes in HIV Infection

    Constantine G. Lyketsos;Donald R. Hoover;Marcella Guccione;Walton Senterfitt

  • Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA.

    Angela K. Talley;Stephen Dewhurst;Seth W. Perry;Sheila C. Dollard

  • Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo.

    Peter Westervelt;D. B. Trowbridge;L. G. Epstein;B. M. Blumberg

  • Human herpesvirus 6 limbic encephalitis after stem cell transplantation.

    Mark S. Wainwright;Paul L. Martin;Richard P. Morse;Mary Lacaze

  • Hippocampal sclerosis after febrile status epilepticus: The FEBSTAT study

    Darrell V. Lewis;Shlomo Shinnar;Dale C. Hesdorffer;Emilia Bagiella

  • HIV-1 V3 domain variation in brain and spleen of children with AIDS: tissue-specific evolution within host-determined quasispecies.

    Leon G. Epstein;Carla Kuiken;Benjamin M. Blumberg;Susan Hartman

  • Multinucleated giant cells and HTLV-III in AIDS encephalopathy

    Leroy R. Sharer;Eun-Sook Cho;Eun-Sook Cho;Leon G. Epstein;Leon G. Epstein

Frequent Co-Authors

Harris A. Gelbard
Harris A. Gelbard University of Rochester Medical Center
Justin C. McArthur
Justin C. McArthur Johns Hopkins University School of Medicine
Bruce Cohen
Bruce Cohen Northwestern University
Jaap Goudsmit
Jaap Goudsmit Harvard University
Stephen Dewhurst
Stephen Dewhurst University of Rochester
Michael P. McDermott
Michael P. McDermott University of Rochester
Robert R. Edelman
Robert R. Edelman Northwestern University
Karl Kieburtz
Karl Kieburtz University of Rochester Medical Center
Karen Marder
Karen Marder Columbia University
James M. Oleske
James M. Oleske Rutgers, The State University of New Jersey

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