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Göran Akusjärvi

Göran Akusjärvi

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
7709
World Ranking
18447
National Ranking
289

Overview

Göran Akusjärvi is affiliated with Uppsala University in Sweden and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their research output includes a total of 19 publications focused primarily on molecular biology and genetics, with additional work in immunology, cardiology and cardiovascular medicine, and animal science and zoology.

The scientist's most frequent research topics encompass RNA research and splicing, RNA modifications and cancer, virus-based gene therapy, nuclear structure and function, interferon and immune responses, RNA and protein synthesis mechanisms, and viral infections and immunology research.

Göran Akusjärvi's recent publications include the following:

  • Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections, 2020, Viruses
  • The Human Adenovirus 2 Transcriptome: an Amazing Complexity of Alternatively Spliced mRNAs, 2020, Journal of Virology
  • Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs, 2020, Viruses
  • ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression, 2022, Frontiers in Immunology
  • The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts, 2023, Journal of Biological Chemistry

Frequent co-authors in their research include:

  • Tanel Punga
  • Zamaneh Hajikhezri
  • Mahmoud Darweesh
  • Shady Younis
  • Leif Andersson

The scholarly work of Göran Akusjärvi has been published in a variety of journals, with repeated contributions to:

  • Viruses
  • Journal of Virology
  • Frontiers in Immunology
  • Journal of Biological Chemistry
  • Cancer Gene Therapy

The research primarily emphasizes viral infections, adenovirus biology, RNA processing mechanisms, and their implications in immune response and cancer pathways. The work encompasses detailed molecular studies of RNA binding proteins, zinc finger proteins, and alternative splicing events in adenovirus transcriptomes.

Best Publications

  • Suppression of RNA Interference by Adenovirus Virus-Associated RNA

    M. Gunnar Andersson;P. C. Joost Haasnoot;Ning Xu;Saideh Berenjian

  • Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

    Michel Perricaudet;Göran Akusjärvi;Anders Virtanen;Ulf Pettersson

  • Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

    T Carvalho;J S Seeler;K Ohman;P Jordan

  • Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA

    Arvydas Kanopka;Oliver Mühlemann;Göran Akusjärvi

  • Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

    Arvydas Kanopka;Oliver Mühlemann;Svend Petersen-Mahrt;Camilla Estmer

  • The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA

    Peter Aleström;Goran Akusjärvi;Michel Perricaudet;Michael B. Mathews

  • The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation.

    Svend K. Petersen-Mahrt;Camilla Estmer;Christina Öhrmalm;David A. Matthews

  • Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

    Oleg Dyachok;Olof Idevall-Hagren;Jenny Sågetorp;Geng Tian

  • Controls of RNA splicing and termination in the major late adenovirus transcription unit.

    Göran Akusjärvi;Håkan Persson

  • Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2

    G Akusjärvi;M B Mathews;P Andersson;B Vennström

  • The sequence of the 3′ non-coding region of the hexon mRNA discloses a novel adenovirus gene

    Göran Akusjärvi;Jan Zabielski;Michel Perricaudet;Ulf Pettersson

  • Adenovirus 3 fiber polypeptide gene: implications for the structure of the fiber protein.

    C Signäs;G Akusjärvi;U Pettersson

  • The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins

    Camilla Estmer Nilsson;Svend Petersen‐Mahrt;Svend Petersen‐Mahrt;Céline Durot;Ronit Shtrichman;Ronit Shtrichman

  • Adenovirus virus-associated RNAII-derived small RNAs are efficiently incorporated into the rna-induced silencing complex and associate with polyribosomes.

    Ning Xu;Bo Segerman;Xiaofu Zhou;Göran Akusjärvi

  • A Consensus Sequence for the Adenovirus-2 Genome

    R. J. Roberts;G. Akusjarvi;P. Alestrom;R. E. Gelinas

  • Cisplatin Induces the Proapoptotic Conformation of Bak in a ΔMEKK1-Dependent Manner

    Aleksandra Mandic;Kristina Viktorsson;Magnus Molin;Göran Akusjärvi

  • Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs.

    K Nordqvist;K Ohman;G Akusjärvi

  • A novel adenovirus-2 E1A mRNA encoding a protein with transcription activation properties.

    P. J. Ulfendahl;S. Linder;J. P. Kreivi;K. Nordqvist

  • Sequence analysis of adenovirus DNA: Complete nucleotide sequence of the spliced 5′ noncoding region of adenovirus 2 hexon messenger RNA

    Göran Akusjärvi;Ulf Pettersson

  • Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter.

    M Bondesson;K Ohman;M Manervik;S Fan

Frequent Co-Authors

Ulf Pettersson
Ulf Pettersson Uppsala University
Stig Linder
Stig Linder Linköping University
Camilla I. Svensson
Camilla I. Svensson Karolinska Institute
Michel Perricaudet
Michel Perricaudet Institut Gustave Roussy
Leif Andersson
Leif Andersson Texas A&M University
Gunnar Andersson
Gunnar Andersson Stockholm University
Louis H. Philipson
Louis H. Philipson University of Chicago
Stefan Schwartz
Stefan Schwartz Lund University
David A. Matthews
David A. Matthews University of Bristol
Richard J. Roberts
Richard J. Roberts New England Biolabs

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