World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
70
Citations
15257
World Ranking
1961
National Ranking
830

Molecular Biology

D-Index
70
Citations
15258
World Ranking
1436
National Ranking
730

Overview

William S. M. Wold is a researcher affiliated with Saint Louis University in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant focus on Epidemiology, Genetics, Infectious Diseases, Cardiology and Cardiovascular Medicine, and Immunology.

Their research topics cover a range of areas including:

  • Cytomegalovirus and herpesvirus research
  • Virus-based gene therapy research
  • Herpesvirus infections and treatments
  • Viral infections and immunology research
  • Respiratory viral infections research
  • Immunodeficiency and autoimmune disorders
  • SARS-CoV-2 and COVID-19 research

Recent papers authored or coauthored by William S. M. Wold include:

  • Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses, 2020, Antimicrobial Agents and Chemotherapy
  • Generation and characterization of an IL2RG knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients, 2020, Disease Models & Mechanisms
  • NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin, 2022, Molecular Pharmaceutics
  • Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters, 2024, Antiviral Research
  • Oral Usc-093, a Novel Homoserinamide Analogue of the Tyrosinamide (S)-Hpmpa Prodrug Usc-087 Has Decreased Nephrotoxicity While Maintaining Antiviral Efficacy Against Human Adenovirus Infection of Syrian Hamsters, 2023, SSRN Electronic Journal

Frequent coauthors collaborating with William S. M. Wold include:

  • Jacqueline F. Spencer
  • Ann E. Tollefson
  • Károly Tóth
  • Baoling Ying
  • Mark N. Prichard

Their publications have appeared in several distinct scientific venues, such as:

  • Molecular Pharmaceutics
  • Antimicrobial Agents and Chemotherapy
  • Disease Models & Mechanisms
  • Antiviral Research
  • SSRN Electronic Journal

Best Publications

  • Adenovirus Vectors for Gene Therapy, Vaccination and Cancer Gene Therapy

    William S M Wold;Karoly Toth

  • The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells.

    A E Tollefson;A Scaria;T W Hermiston;J S Ryerse

  • The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha

    Eileen White;P. Sabbatini;M. Debbas;W. S.M. Wold

  • Role of early region 3 (E3) in pathogenesis of adenovirus disease.

    Harold S. Ginsberg;Ulla Lundholm-Beauchamp;Robert L. Horswood;Benvenuto Pernis

  • Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions.

    William S.M. Wold;Linda R. Gooding

  • A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor

    Linda R. Gooding;Lynne W. Elmore;Ann E. Tollefson;Helen A. Brady

  • The E3-11.6-kDa Adenovirus Death Protein (ADP) Is Required for Efficient Cell Death: Characterization of Cells Infected withadpMutants

    Ann E. Tollefson;Jan S. Ryerse;Abraham Scaria;Terry W. Hermiston

  • Tumor-Specific, Replication-Competent Adenovirus Vectors Overexpressing the Adenovirus Death Protein

    Konstantin Doronin;Karoly Toth;Mohan Kuppuswamy;Peter Ward

  • Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells

    Ann E. Tollefson;Terry W. Hermiston;Terry W. Hermiston;Drew L. Lichtenstein;Clarence F. Colle

  • Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

    William Sm Wold;Konstantin Doronin;Karoly Toth;Mohan Kuppuswamy

  • A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum.

    Svante Pääbo;Bheem M. Bhat;William S.M. Wold;Per A. Peterson

  • FUNCTIONS AND MECHANISMS OF ACTION OF THE ADENOVIRUS E3 PROTEINS

    Drew L. Lichtenstein;Karoly Toth;Konstantin Doronin;Ann E. Tollefson

  • Immunological identification of two adenovirus 2-induced early proteins possibly involved in cell transformation.

    Zvee Gilead;Yun Hua Jeng;William S M Wold;Kenji Sugawara

  • Thirty-one human adenovirus serotypes (Ad1-Ad31) form five groups (A-E) based upon DNA genome homologies.

    Maurice Green;Jesse K. Mackey;William S.M. Wold;Patricia Rigden

  • Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors.

    Maria A. Thomas;Jacqueline F. Spencer;Marie C. La Regina;Debanjan Dhar

  • The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor.

    L. R. Gooding;T. S. Ranheim;A. E. Tollefson;L. Aquino

  • Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy

    Konstantin Doronin;Mohan Kuppuswamy;Karoly Toth;Ann E. Tollefson

  • Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor.

    P Duerksen-Hughes;W S Wold;L R Gooding

  • Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus.

    Konstantin Doronin;Karoly Toth;Mohan Kuppuswamy;Peter Krajcsi

  • Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

    Maria A Thomas;Jacqueline F Spencer;Karoly Toth;John E Sagartz

  • Activation of intracellular proteases is an early event in TNF-induced apoptosis.

    C. Voelkel-Johnson;A. J. Entingh;W. S. M. Wold;L. R. Gooding

Frequent Co-Authors

Maurice Green
Maurice Green Saint Louis University
Nicholas R. Lemoine
Nicholas R. Lemoine Queen Mary University of London
Ralph A. Tripp
Ralph A. Tripp University of Georgia
Gregory A. Prince
Gregory A. Prince National Institutes of Health
Carl W. Anderson
Carl W. Anderson Brookhaven National Laboratory
G. Chinnadurai
G. Chinnadurai Saint Louis University
Gérard Orth
Gérard Orth Institut Pasteur
John C. Hierholzer
John C. Hierholzer Centers for Disease Control and Prevention
Elliot J. Lefkowitz
Elliot J. Lefkowitz University of Alabama at Birmingham
Eileen White
Eileen White Rutgers, The State University of New Jersey

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students interested in molecular biology often explore related disciplines and alternative science careers. Many fields offer online degree pathways, making transitions smoother for motivated students from various academic backgrounds.

For example, those curious about the healthcare side of science may consider asha accredited slpa programs. These fully online options provide an accelerated route to careers in speech-language pathology, ensuring standards required by the American Speech-Language-Hearing Association are met.

If you hold a non-slp bachelor's degree but want to pivot careers, several speech pathology bridge programs online can help you meet prerequisites quickly and efficiently.

Similarly, those outside of nursing, but interested in healthcare, may choose non nursing degree to bsn online programs, which let students earn a nursing degree in a reduced timeframe.

Career paths can lead toward advanced practice as well. For example, a DNP can open doors in psychiatric nursing—explore average earnings with this guide to dnp psychiatric nurse practitioner salary by state.

Best Scientists Citing William S. M. Wold

Trending Scientists