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D-Index
41
Citations
4826
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17814
National Ranking
1407

Overview

Shunji Aoki is affiliated with Hyogo University of Health Sciences in Japan. Their research predominantly covers topics within the fields of Medicine and Environmental Science, with particular focus on Environmental Chemistry and Sensory Systems, as well as Complementary and Alternative Medicine, Biochemistry, and Pharmacology as subfields.

The main research topics addressed by Shunji Aoki include:

  • Ion Channels and Receptors
  • Herbal Medicine Research Studies
  • Phytochemicals and Antioxidant Activities
  • Piperaceae Chemical and Biological Studies
  • Essential Oils and Antimicrobial Activity
  • Antibiotic Resistance in Bacteria
  • Aquatic Ecosystems and Phytoplankton Dynamics

The scientist's publication record comprises recent papers in several distinct journals. These include:

  • "Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation," published in 2021 in the International Journal of Molecular Sciences
  • "Piperine, an active ingredient of white pepper, suppresses the growth of multidrug-resistant toxigenic Vibrio cholerae and other pathogenic bacteria," published in 2022 in Letters in Applied Microbiology
  • "Acteoside from Conandron ramondioides Reduces Microcystin-LR Cytotoxicity by Inhibiting Intracellular Uptake Mediated by OATP1B3," published in 2023 in Planta Medica

Frequent publication venues for Shunji Aoki's work are:

  • International Journal of Molecular Sciences
  • Letters in Applied Microbiology
  • Planta Medica

Among frequent coauthors, the following collaborators have appeared multiple times or contributed to significant works alongside Aoki:

  • Emiko Iwaoka
  • Hirosato Kanda
  • Yanjing Yang
  • Shaoqi Duan
  • Yoko Kogure

The publication topics suggest a strong interdisciplinary approach combining studies in pharmacological mechanisms, antimicrobial resistance, and environmental toxicology. Specific research has examined bioactive compounds such as atractylodin affecting ion channels, piperine's antibacterial properties against resistant bacteria, and the cytotoxic reduction of microcystin toxins through natural plant derivatives.

Best Publications

  • Cortistatins A, B, C, and D, Anti-angiogenic Steroidal Alkaloids, from the Marine Sponge Corticium simplex

    Shunji Aoki;Yasuo Watanabe;Mami Sanagawa;Andi Setiawan

  • Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter

    Zhe Sheng Chen;Takeshi Kawabe;Mayumi Ono;Shunji Aoki;Shunji Aoki

  • Marine natural products. XXXIV. Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum.

    Motomasa Kobayashi;Shunji Aoki;Katsuhiko Gato;Katsuyoshi Matsunami

  • Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum

    Motomasa Kobayashi;Shunji Aoki;Haruhiko Sakai;Kazuyoshi Kawazoe

  • ARENASTATIN A, A POTENT CYTOTOXIC DEPSIPEPTIDE FROM THE OKINAWAN MARINE SPONGE DYSIDEA ARENARIA

    Motomasa Kobayashi;Shunji Aoki;Naoki Ohyabu;Michio Kurosu

  • Absolute stereostructures of altohyrtin A and its congeners, potent cytotoxic macrolides from the Okinawan marine sponge hyrtios altum

    Motomasa Kobayashi;Shunji Aoki;Isao Kitagawa

  • Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids.

    Shunji Aoki;Yasuo Watanabe;Daiki Tanabe;Masayoshi Arai

  • Callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

    Motomasa Kobayashi;Kouichi Higuchi;Nobutoshi Murakami;Hisashi Tajima

  • Cortistatins E, F, G, and H, four novel steroidal alkaloids from marine sponge Corticium simplex

    Yasuo Watanabe;Shunji Aoki;Daiki Tanabe;Andi Setiawan

  • Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum.

    Motomasa Kobayashi;Shunji Aoki;Haruhiko Sakai;Noriaki Kihara

  • Cortistatins J, K, L, novel abeo-9(10-19)-androstane-type steroidal alkaloids with isoquinoline unit, from marine sponge Corticium simplex

    Shunji Aoki;Yasuo Watanabe;Daiki Tanabe;Andi Setiawan

  • Melophlins A and B, Novel Tetramic Acids Reversing the Phenotype of ras-Transformed Cells, from the Marine Sponge Melophlus sarassinorum

    Shunji Aoki;Kouichi Higuchi;Ying Ye;Rachmaniar Satari

  • Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells

    Motoi Mukai;Xiao Fang Che;Tatsuhiko Furukawa;Tomoyuki Sumizawa

  • Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs.

    Syuhei Nakao;Miyuki Mabuchi;Tadashi Shimizu;Yoshihiro Itoh

  • Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp.

    Shunji Aoki;Yasuhiro Yoshioka;Yasuhisa Miyamoto;Kouichi Higuchi

  • New Rev-transport inhibitor with anti-HIV activity from Valerianae Radix

    Nobutoshi Murakami;Ying Ye;Motoyuki Kawanishi;Shunji Aoki

  • Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis.

    Shunji Aoki;Hong Wei;Kouhei Matsui;Rachmaniar Rachmat

  • Marine Natural Products. XXXVIII. Absolute Stereostructures of Altohyrtins A, B, and C and 5-Desacetylaltohyrtin A, Potent Cytotoxic Macrolides, from the Okinawan Marine Sponge Hyrtios altum.

    Motomasa Kobayashi;Shunji Aoki;Katsuhiko Gato;Isao Kitagawa

  • Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner.

    Shunji Aoki;Dexin Kong;Hideaki Suna;Yoshihiro Sowa

  • Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function.

    Zhe-Sheng Chen;Shunji Aoki;Masaharu Komatsu;Kazumitsu Ueda

  • Absolute stereostructure of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

    Nobutoshi Murakami;Weiqi Wang;Masashi Aoki;Yasuhiro Tsutsui

Frequent Co-Authors

Motomasa Kobayashi
Motomasa Kobayashi Osaka University
Isao Kitagawa
Isao Kitagawa Osaka University
Tatsuhiko Furukawa
Tatsuhiko Furukawa Kagoshima University
Tomoyuki Sumizawa
Tomoyuki Sumizawa Kagoshima University
Zhe-Sheng Chen
Zhe-Sheng Chen St. John's University
Shin-ichi Akiyama
Shin-ichi Akiyama Kagoshima University
Toshiyuki Sakai
Toshiyuki Sakai Kyoto Prefectural University of Medicine
Yi Dai
Yi Dai Hyogo University of Health Sciences
Shinsaku Nakagawa
Shinsaku Nakagawa Osaka University
Koichi Noguchi
Koichi Noguchi Hyogo College of Medicine

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