Shin-ichi Akiyama

Overview

Best Publications

• A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation

  Ken Taniguchi;Morimasa Wada;Kimitoshi Kohno;Takanori Nakamura

  695
  Citations

• Reduced Drug Accumulation in Multiply Drug-resistant Human KB Carcinoma Cell Lines

  Antonio Fojo;Shin-ichi Akiyama;Michael M. Gottesman;Ira Pastan

  645
  Citations

• Angiogenic activity of enzymes

  Misako Haraguchi;Kazutaka Miyadera;Katsuo Uemura;Tomoyuki Sumizawa

  492
  Citations

• Clinicopathologic and Prognostic Significance of an Angiogenic Factor, Thymidine Phosphorylase, in Human Colorectal Carcinoma

  Yuji Takebayashi;Shin-ichi Akiyama;Suminori Akiba;Kazutaka Yamada

  490
  Citations

• Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance

  Masaharu Komatsu;Tomoyuki Sumizawa;Masato Mutoh;Zhe-Sheng Chen

  462
  Citations

• Role of Thymidine Phosphorylase Activity in the Angiogenic Effect of Platelet-derived Endothelial Cell Growth Factor/Thymidine Phosphorylase

  Kazutaka Miyadera;Tomoyuki Sumizawa;Misako Haraguchi;Hiroki Yoshida

  388
  Citations

• Multidrug Resistance and the Lung Resistance-Related Protein in Human Colon Carcinoma SW-620 Cells

  Masaki Kitazono;Tomoyuki Sumizawa;Yuji Takebayashi;Zhe-Sheng Chen

  271
  Citations

• Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter

  Zhe Sheng Chen;Takeshi Kawabe;Mayumi Ono;Shunji Aoki;Shunji Aoki

  258
  Citations

• Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

  Akihiko Yoshimura;Yasuo Kuwazuru;Tatsuhiko Furukawa;Hiroki Yoshida

  241
  Citations

• Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2).

  Takeshi Kawabe;Zhe Sheng Chen;Morimasa Wada;Takeshi Uchiumi

  224
  Citations

• Expression of the multidrug transporter, P-glycoprotein, in acute leukemia cells and correlation to clinical drug resistance

  Yasuo Kuwazuru;Akihiko Yoshimura;Shuichi Hanada;Atae Utsunomiya

  208
  Citations

• Breast Cancer Resistance Protein (BCRP/ABCG2) Induces Cellular Resistance to HIV-1 Nucleoside Reverse Transcriptase Inhibitors

  Xin Wang;Tatsuhiko Furukawa;Takao Nitanda;Mika Okamoto

  205
  Citations

• Thymidine phosphorylase activity associated with platelet-derived endothelial cell growth factor.

  Tomoyuki Sumizawa;Tatsuhiko Furukawa;Misako Haraguchi;Akihiko Yoshimura

  201
  Citations

• Elevated expression of vacuolar proton pump genes and cellular PH in cisplatin resistance.

  Tadashi Murakami;Izumi Shibuya;Tomoko Ise;Zhe-Sheng Chen

  197
  Citations

• Involvement of Mitogen-Activated Protein Kinase Signaling Pathways in Microcystin-LR–Induced Apoptosis after its Selective Uptake Mediated by OATP1B1 and OATP1B3

  Masaharu Komatsu;Tatsuhiko Furukawa;Ryuji Ikeda;Shota Takumi

  192
  Citations

• Cytoplasmic orientation and two-domain structure of the multidrug transporter, P-glycoprotein, demonstrated with sequence-specific antibodies.

  A Yoshimura;Y Kuwazuru;T Sumizawa;M Ichikawa

  180
  Citations

• Expression of thymidine phosphorylase in human gastric carcinoma.

  Yuji Takebayashi;Kazutaka Miyadera;Shin-ichi Akiyama;Shuichi Hokita

  161
  Citations

• Lung resistance protein (LRP) expression in human normal tissues in comparison with that of MDR1 and MRP.

  Isamu Sugawara;Shinichi Akiyama;Rik J. Scheper;Shinji Itoyama

  160
  Citations

• Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane.

  Jill K. Paterson;Suneet Shukla;Chelsea M. Black;Tokushi Tachiwada

  154
  Citations

• The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression

  Shin-ichi Akiyama;Tatsuhiko Furukawa;Tomoyuki Sumizawa;Yuji Takebayashi

  142
  Citations