World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
48
Citations
5392
World Ranking
6280
National Ranking
2735

Overview

Lorraine Iacovitti is affiliated with Thomas Jefferson University in the United States. Their research spans multiple disciplines within the life sciences, particularly focusing on neuroscience, biochemistry, genetics, and molecular biology. The scientist's work integrates various subfields such as molecular biology, neurology, genetics, cellular and molecular neuroscience, and developmental neuroscience.

Research topics frequently addressed in their publications include:

  • Neuroinflammation and neurodegeneration mechanisms
  • Extracellular vesicles in disease
  • Neuroscience and neuropharmacology research
  • Mesenchymal stem cell research
  • Neurogenesis and neuroplasticity mechanisms
  • MicroRNA in disease regulation
  • Glioma diagnosis and treatment

Some of the scientist's more recent publications are:

  • "Facial grimace testing as an assay of neuropathic pain-related behavior in a mouse model of cervical spinal cord injury," 2020, published in Experimental Neurology
  • "Most recent advances and applications of extracellular vesicles in tackling neurological challenges," 2024, published in Medicinal Research Reviews
  • "GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults," 2024, published in npj Parkinson's Disease
  • "A stress-free strategy to correct point mutations in patient iPS cells," 2021, published in Stem Cell Research
  • "Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires repeated handling," 2024, published in PLoS ONE

The primary venues for this researcher's work include:

  • Experimental Neurology
  • Medicinal Research Reviews
  • PLoS ONE
  • npj Parkinson's Disease
  • Translational Stroke Research

Collaborations are a significant part of their research practice, with frequent co-authors being:

  • Yolanda Gómez-Gálvez
  • Elena Blanco-Suárez
  • Salvatore Fusco
  • Claudio Grassi
  • Amit K. Srivastava

This profile highlights the scientist's multidisciplinary approach in exploring neurological conditions and molecular mechanisms underlying neurodegeneration, stem cell biology, and cellular communication via extracellular vesicles. Their work contributes to understanding complex biological processes relevant to disease and therapy development.

Best Publications

  • Circumventricular Organs: A Novel Site of Neural Stem Cells in the Adult Brain

    Lori Bennett;Ming Yang;Grigori Enikolopov;Lorraine Iacovitti

  • Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats.

    Jingli Cai;Ming Yang;Elizabeth Poremsky;Sarah Kidd

  • A PROTOCOL FOR THE DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO DOPAMINERGIC NEURONS USING ONLY CHEMICALLY DEFINED HUMAN ADDITIVES: STUDIES IN VITRO AND IN VIVO

    Lorraine Iacovitti;Angela E. Donaldson;Cheryl E. Marshall;Sokreine Suon

  • N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data.

    Daniel A. Monti;George Zabrecky;Daniel Kremens;Tsao-Wei Liang

  • Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.

    Ming Yang;Natalie D. Stull;Mathew A. Berk;Evan Y. Snyder

  • Neurogenesis is enhanced by stroke in multiple new stem cell niches along the ventricular system at sites of high BBB permeability

    Ruihe Lin;Jingli Cai;Cody Nathan;Xiaotao Wei

  • Synergy between growth factors and transmitters required for catecholamine differentiation in brain neurons

    Xinyu Du;L. Iacovitti

  • Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats.

    Ming Yang;Xiaotao Wei;Jing Li;Lynn A Heine

  • Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress

    Lorraine Iacovitti;Natalie D Stull;Kelly Johnston

  • The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model.

    Jingli Cai;Angela E Donaldson;Ming Yang;Michael S German

  • Classic and novel stem cell niches in brain homeostasis and repair.

    Ruihe Lin;Lorraine Iacovitti

  • Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (ΔE) TorsinA in transgenic mice

    Michelle E. Page;Li Bao;Pierrette Andre;Joshua Pelta-Heller

  • Expression of tyrosine hydroxylase in neurons of cultured cerebral cortex: evidence for phenotypic plasticity in neurons of the CNS

    L Iacovitti;J Lee;TH Joh;DJ Reis

  • Brain-derived neurotrophic factor works coordinately with partner molecules to initiate tyrosine hydroxylase expression in striatal neurons

    Xinyu Du;Natalie D. Stull;Lorraine Iacovitti

  • Dual expression of neurotransmitter synthesis in cultured autonomic neurons

    L Iacovitti;TH Joh;DH Park;RP Bunge

  • Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation

    Svetlana Petruk;Jingli Cai;Robyn Sussman;Guizhi Sun

  • The human tyrosine hydroxylase gene promoter.

    Mark A. Kessler;Ming Yang;Kandace L. Gollomp;Hao Jin

  • Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

    Yulan Xiong;Stewart Neifert;Senthilkumar S. Karuppagounder;Qinfang Liu

  • Regulation of tyrosine hydroxylase gene expression during transdifferentiation of striatal neurons: changes in transcription factors binding the AP-1 site.

    Zheng Guo;Xinyu Du;Lorraine Iacovitti

  • Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model.

    Chia-Hsuan Fu;Daniel Maxim Iascone;Iraklis Petrof;Iraklis Petrof;Anupam Hazra

  • Expression of tyrosine hydroxylase in newly differentiated neurons from a human cell line (hNT).

    Lorraine Iacovitti;Natalie D. Stull

  • Transient differentiation of adult human bone marrow cells into neuron-like cells in culture: development of morphological and biochemical traits is mediated by different molecular mechanisms.

    Sokreine Suon;Hao Jin;Angela E Donaldson;E J Caterson

Frequent Co-Authors

Donald J. Reis
Donald J. Reis Cornell University
Tong H. Joh
Tong H. Joh Cornell University
Ashwini Sharan
Ashwini Sharan Thomas Jefferson University
Harold Burton
Harold Burton Washington University in St. Louis
Angelo C. Lepore
Angelo C. Lepore Thomas Jefferson University
Jeannie Chin
Jeannie Chin Baylor College of Medicine
Jin-Moo Lee
Jin-Moo Lee Washington University in St. Louis
Jay S. Schneider
Jay S. Schneider University of Pennsylvania
Bryce Vissel
Bryce Vissel St Vincent's Hospital Sydney
Valina L. Dawson
Valina L. Dawson Johns Hopkins University School of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring neuroscience can open doors to diverse online degree options and specialized career paths in the USA. If you’re interested in advancing to clinical or counseling roles, pursuing an online psy d program is a strong choice. These programs are designed for those aiming at psychologist licensure and private practice.

For those interested in therapy and family dynamics, online mft programs (Marriage and Family Therapy) provide flexible routes to licensure in a growing mental health field. Many programs now offer accelerated formats for quicker completion.

If you want to save time and enter the workforce sooner, consider 2 year accelerated bachelor degrees in related fields such as psychology or biology. These degrees can help you build foundational knowledge for graduate work or entry-level positions in neuroscience and allied sectors.

Lastly, students eager to maximize earning potential may want to review the top paying degrees at the bachelor’s level. Fields related to neuroscience, such as engineering and computer science, consistently rank among the highest earning options for graduates.

Best Scientists Citing Lorraine Iacovitti

Trending Scientists

Recently Published Articles