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Microbiology

D-Index
52
Citations
10884
World Ranking
4182
National Ranking
374

Overview

Peter Balfe is affiliated with the University of Oxford in the United Kingdom. Their research spans Medicine and Biochemistry, Genetics and Molecular Biology, with a primary focus on epidemiology, molecular biology, hepatology, cancer research, and infectious diseases.

Their work explores several main topics, including hepatitis B virus studies, hepatitis C virus research, cancer, hypoxia, and metabolism, liver disease diagnosis and treatment, circadian rhythm and melatonin, tryptophan and brain disorders, and RNA modifications and cancer.

Selected recent publications by Peter Balfe include the following:

  • Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells (2021) published in Cell Reports
  • Time of Day of Vaccination Affects SARS-CoV-2 Antibody Responses in an Observational Study of Health Care Workers (2021) published in Journal of Biological Rhythms
  • Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter (2021) published in Journal of Hepatology
  • Circadian control of hepatitis B virus replication (2021) published in Nature Communications
  • Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication (2020) published in Scientific Reports

Their frequent coauthors include:

  • Jane A. McKeating
  • James Michael Harris
  • Peter A. C. Wing
  • Xiaodong Zhuang
  • Andrea Magrì

Peter Balfe often publishes their research in venues such as bioRxiv (Cold Spring Harbor Laboratory), Viruses, Nature Communications, PLoS Pathogens, and iScience. Their contributions have made an interdisciplinary link between virology, immunology, and molecular mechanisms underlying infectious diseases and cancer.

Best Publications

  • Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers.

    P Simmonds;P Balfe;J F Peutherer;C A Ludlam

  • Neutralizing antibody response during acute and chronic hepatitis C virus infection

    Carine Logvinoff;M E Major;D Oldach;S Heyward

  • Hepatitis C Virus Continuously Escapes From Neutralizing Antibody and T-Cell Responses During Chronic Infection In Vivo

    Thomas von Hahn;Joo Chun Yoon;Harvey Alter;Charles M. Rice

  • Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies.

    Jennifer M. Timpe;Zania Stamataki;Adam Jennings;Ke Hu

  • Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1.

    Peter Simmonds;P Balfe;Ca Ludlam;Jo Bishop

  • Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

    Claire L. Brimacombe;Joe Grove;Luke W. Meredith;Ke Hu

  • Concurrent evolution of human immunodeficiency virus type 1 in patients infected from the same source: rate of sequence change and low frequency of inactivating mutations.

    P Balfe;Peter Simmonds;Ca Ludlam;Jo Bishop

  • Claudin Association with CD81 Defines Hepatitis C Virus Entry

    Helen J Harris;Christopher Davis;Jonathan G L Mullins;Ke Hu

  • CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry

    Helen J. Harris;Michelle J. Farquhar;Christopher J. Mee;Christopher Davis

  • Discontinuous sequence change of human immunodeficiency virus (HIV) type 1 env sequences in plasma viral and lymphocyte-associated proviral populations in vivo: implications for models of HIV pathogenesis.

    P. Simmonds;Lin Qi Zhang;F. Mcomish;P. Balfe

  • Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier

    Nicola F. Fletcher;Garrick K. Wilson;Jacinta Murray;Ke Hu

  • Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users.

    P Simmonds;S Rebus;G.H Leadbetter;J.F Peutherer

  • Diverse Hepatitis C Virus Glycoproteins Mediate Viral Infection in a CD81-Dependent Manner

    Jane A McKeating;L Q Zhang;L Q Zhang;C Logvinoff;M Flint

  • Diverse CD81 Proteins Support Hepatitis C Virus Infection

    Mike Flint;Thomas von Hahn;Jie Zhang;Michelle Farquhar

  • Genetic analysis of human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) mixed infections in India reveals a recent spread of HIV-1 and HIV-2 from a single ancestor for each of these viruses.

    M Grez;U Dietrich;P Balfe;H von Briesen

  • Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity

    Joe Grove;Thierry Huby;Zania Stamataki;Thomas Vanwolleghem

  • Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120.

    J A McKeating;C Shotton;J Cordell;S Graham

  • Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies

    Joe Grove;Søren Nielsen;Jin Zhong;Margaret F. Bassendine

  • Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis

    Michelle J. Farquhar;Ke Hu;Helen J. Harris;Christopher Davis

  • Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in china.

    Linqi Zhang;Zhiwei Chen;Yunzhen Cao;Yunzhen Cao;Jian Yu

Frequent Co-Authors

Jane A. McKeating
Jane A. McKeating University of Oxford
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg
Peter Simmonds
Peter Simmonds University of Oxford
Stefan G. Hubscher
Stefan G. Hubscher University of Birmingham
Charles M. Rice
Charles M. Rice Rockefeller University
Andrew J. Leigh Brown
Andrew J. Leigh Brown University of Edinburgh
Koichi Watashi
Koichi Watashi National Institute of Infectious Diseases
Persephone Borrow
Persephone Borrow University of Oxford
Peter J. Ratcliffe
Peter J. Ratcliffe The Francis Crick Institute
Ulrike Protzer
Ulrike Protzer Technical University of Munich

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