World's Best Scientists 2026 revealed!
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Microbiology
Czechia
2026

D-Index & Metrics

Microbiology

D-Index
53
Citations
8726
World Ranking
4125
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Microbiology in Czechia Leader Award
  • 2025 - Research.com Microbiology in Czechia Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Peter Sebo is affiliated with the Czech Academy of Sciences in the Czech Republic. Their research spans multiple interconnected fields, primarily focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these fields, their work concentrates on subfields such as Microbiology, Epidemiology, Molecular Biology, Endocrinology, and Infectious Diseases.

The scientist's research topics encompass various areas including Bacterial Infections and Vaccines, Pneumonia and Respiratory Infections, Escherichia coli research studies, Peripheral Neuropathies and Disorders, Influenza Virus Research Studies, Bacterial Genetics and Biotechnology, and Streptococcal Infections and Treatments.

Peter Sebo has contributed to several recent publications, with notable papers including:

  • Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis (2023, Cell Reports)
  • Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice (2020, Vaccines)
  • Overcoming Waning Immunity in Pertussis Vaccines: Workshop of the National Institute of Allergy and Infectious Diseases (2020, The Journal of Immunology)
  • Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue (2020, PLoS Pathogens)
  • Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins (2020, Journal of Biological Chemistry)

The scientist frequently publishes in venues such as the Journal of Biological Chemistry, mSphere, PLoS Pathogens, International Journal of Molecular Sciences, and Frontiers in Immunology.

Peter Sebo collaborates regularly with several coauthors, including Jana Holubová, Radim Osička, Ondřej Staněk, Ladislav Bumba, and Jiří Mašín, with whom they have numerous joint publications.

Recognition of their work includes membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • RTX proteins: a highly diverse family secreted by a common mechanism.

    Irena Linhartová;Ladislav Bumba;Jiří Mašín;Marek Basler

  • Bordetella adenylate cyclase toxin: a swift saboteur of host defense.

    Jana Vojtova;Jana Kamanova;Peter Sebo

  • Interaction of Calcium with Bordetella pertussis Adenylate Cyclase Toxin CHARACTERIZATION OF MULTIPLE CALCIUM-BINDING SITES AND CALCIUM-INDUCED CONFORMATIONAL CHANGES

    Thierry Rose;Peter Sebo;Jacques Bellalou;Daniel Ladant

  • Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli.

    R Benz;E Maier;D Ladant;A Ullmann

  • Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis

    Aisling Dunne;Pádraig J. Ross;Eva Pospisilova;Jiri Masin

  • Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain.

    Mohammed El-Azami-El-Idrissi;Cécile Bauche;Jirina Loucka;Radim Osicka

  • Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts

    Ladislav Bumba;Jiri Masin;Pavel Macek;Tomas Wald

  • Delivery of CD8+ T-Cell Epitopes into Major Histocompatibility Complex Class I Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase: Delineation of Cell Invasive Structures and Permissive Insertion Sites

    Radim Osička;Adriana Osičková;Tümay Basar;Pierre Guermonprez

  • Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin.

    Xaver Sewald;Bettina Gebert-Vogl;Sandra Prassl;Iris Barwig

  • In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes.

    C Fayolle;P Sebo;D Ladant;A Ullmann

  • Adenylate Cyclase Toxin Subverts Phagocyte Function by RhoA Inhibition and Unproductive Ruffling

    Jana Kamanova;Olga Kofronova;Jiri Masin;Harald Genth

  • An Increase in Antimycobacterial Th1-Cell Responses by Prime-Boost Protocols of Immunization Does Not Enhance Protection against Tuberculosis

    Laleh Majlessi;Marcela Simsova;Zdenka Jarvis;Priscille Brodin

  • Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities.

    H Sakamoto;J Bellalou;P Sebo;D Ladant

  • RTX cytotoxins recognize β2 integrin receptors through N-linked oligosaccharides

    Jana Morova;Radim Osicka;Jiri Masin;Peter Sebo

  • High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection.

    Sandra Hervas-Stubbs;Sandra Hervas-Stubbs;Laleh Majlessi;Laleh Majlessi;Marcela Simsova;Jana Morova

  • Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus.

    M. F. Saron;C. Fayolle;P. Sebo;D. Ladant

  • CyaC-mediated activation is important not only for toxic but also for protective activities of Bordetella pertussis adenylate cyclase-hemolysin.

    F Betsou;P Sebo;N Guiso

  • An Amphipathic α-Helix Including Glutamates 509 and 516 Is Crucial for Membrane Translocation of Adenylate Cyclase Toxin and Modulates Formation and Cation Selectivity of Its Membrane Channels

    Adriana Osic̆ková;Radim Osic̆ka;Elke Maier;Roland Benz

  • Hemolytic, but Not Cell-invasive Activity, of Adenylate Cyclase Toxin Is Selectively Affected by Differential Fatty-acylation in Escherichia coli

    Murray Hackett;Carthene B. Walker;Lin Guo;Mary C. Gray

  • Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.

    Marek Basler;Jiri Masin;Radim Osicka;Peter Sebo

  • Bordetella pertussis adenylate cyclase: a toxin with multiple talents.

    Sophie Goyard;Peter Šebo;Olivier D'Andria;Daniel Ladant

Frequent Co-Authors

Daniel Ladant
Daniel Ladant Institut Pasteur
Roland Benz
Roland Benz Jacobs University
Agnes Ullmann
Agnes Ullmann Institut Pasteur
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Bernhard Fleischer
Bernhard Fleischer Bernhard Nocht Institute for Tropical Medicine
Katalin A. Wilkinson
Katalin A. Wilkinson The Francis Crick Institute
Kingston H. G. Mills
Kingston H. G. Mills Trinity College Dublin
Volker Heussler
Volker Heussler University of Bern
Nicole Guiso
Nicole Guiso Institut Pasteur

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