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Biology and Biochemistry

D-Index
65
Citations
13535
World Ranking
9253
National Ranking
4094

Overview

Erik L. Hewlett is affiliated with the University of Virginia in the United States. Their research primarily spans the fields of immunology and microbiology, biochemistry, genetics and molecular biology, and medicine. This multidisciplinary approach is reflected in the various topics and subfields associated with their work.

The main fields of study covered by their publications include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader areas, their subfields of study are:

  • Microbiology
  • Endocrinology
  • Immunology
  • Immunology and Allergy
  • Radiology, Nuclear Medicine and Imaging

Erik L. Hewlett's research focuses on several main topics, indicating a strong emphasis on infectious diseases and the immune response. These topics include:

  • Bacterial Infections and Vaccines
  • Cell Adhesion Molecules Research
  • Complement system in diseases
  • Escherichia coli research studies
  • Legionella and Acanthamoeba research
  • Monoclonal and Polyclonal Antibodies Research
  • Force Microscopy Techniques and Applications

The scientist has contributed to several recent papers, highlighting ongoing involvement in investigating microbial pathogenesis and immune mechanisms. Notable recent publications include:

  • "Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils," 2023, Journal of Leukocyte Biology
  • "The CHO Cell Clustering Response to Pertussis Toxin: History of Its Discovery and Recent Developments in Its Use," 2021, Toxins
  • "Four single-basepair mutations in the ptx promoter of Bordetella bronchiseptica are sufficient to activate the expression of pertussis toxin," 2021, Scientific Reports
  • "Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro," 2024, UNC Libraries
  • "Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils," 2022, bioRxiv (Cold Spring Harbor Laboratory)

The venues where Erik L. Hewlett frequently publishes reflect a mix of peer-reviewed journals and institutional repositories, including:

  • UNC Libraries
  • Journal of Leukocyte Biology
  • Toxins
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaboration appears to be a component of their research, with frequent coauthors such as Mary C. Gray, Joshua C. Eby, Asya Smirnov, Kylene P. Daily, and Stephanie A. Ragland appearing in multiple works.

Best Publications

  • A fully integrated microfluidic genetic analysis system with sample-in–answer-out capability

    Christopher J. Easley;James M. Karlinsey;Joan M. Bienvenue;Lindsay A. Legendre

  • Virulence factors of Bordetella pertussis.

    and A A Weiss;E L Hewlett

  • Tn5-induced mutations affecting virulence factors of Bordetella pertussis.

    A A Weiss;E L Hewlett;G A Myers;S Falkow

  • Clinical practice. Pertussis--not just for kids.

    Erik L Hewlett;Kathryn M Edwards

  • Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin.

    E L Hewlett;K T Sauer;G A Myers;J L Cowell

  • Pertussis Toxin and Extracytoplasmic Adenylate Cyclase as Virulence Factors of Bordetella pertussis

    Alison A. Weiss;Erik L. Hewlett;Gwendolyn A. Myers;Stanley Falkow

  • Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin.

    V M Gordon;S H Leppla;E L Hewlett

  • Internal Lysine Palmitoylation in Adenylate Cyclase Toxin from Bordetella pertussis

    Murray Hackett;Lin Guo;Jeffrey Shabanowitz;Donald F. Hunt

  • Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators.

    Guillermo Romero;Louis Luttrell;Alan Rogol;Konrad Zeller

  • ADP-ribosylation of adenylate cyclase by pertussis toxin. Effects on inhibitory agonist binding.

    J A Hsia;J Moss;E L Hewlett;M Vaughan

  • Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells.

    D L Burns;E L Hewlett;J Moss;M Vaughan

  • Whole-Genome Sequencing in Outbreak Analysis

    Carol A. Gilchrist;Stephen D. Turner;Margaret F. Riley;William A. Petri

  • Role of Ni in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes.

    Bonnie F. Pobiner;Erik L. Hewlett;James C. Garrison

  • Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation.

    E M Barry;A A Weiss;I E Ehrmann;M C Gray

  • Rhodopsin-enhanced GTPase activity of the inhibitory GTP-binding protein of adenylate cyclase.

    Y Kanaho;S C Tsai;R Adamik;E L Hewlett

  • Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein).

    J Moss;S J Stanley;D L Burns;J A Hsia

  • Extracytoplasmic adenylate cyclase of Bordetella pertussis.

    E L Hewlett;M A Urban;C R Manclark;J Wolff

  • Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin.

    R D Pearson;P Symes;M Conboy;A A Weiss

  • Niclosamide Therapy for Tapeworm Infections

    Richard D. Pearson;Erik L. Hewlett

  • Adenylate cyclase toxin from Bordetella pertussis: Identification and purification of the holotoxin molecule

    E L Hewlett;V M Gordon;J D McCaffery;J D McCaffery;W M Sutherland

Frequent Co-Authors

Joel Moss
Joel Moss National Institutes of Health
Alison A. Weiss
Alison A. Weiss University of Cincinnati
Michael O. Thorner
Michael O. Thorner University of Virginia
Alan D. Rogol
Alan D. Rogol University of Virginia
Jason A. Papin
Jason A. Papin University of Virginia
Martha Vaughan
Martha Vaughan National Institutes of Health
Paul A. Watkins
Paul A. Watkins Kennedy Krieger Institute
Stanley Falkow
Stanley Falkow Stanford University
William A. Petri
William A. Petri University of Virginia
Richard L. Guerrant
Richard L. Guerrant University of Virginia

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