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Medicine

D-Index
106
Citations
39267
World Ranking
6565
National Ranking
3487

Overview

Pinchas Cohen is affiliated with the University of Southern California in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on subfields such as Physiology, Rheumatology, Molecular Biology, Cancer Research, and Immunology.

Their research topics cover several key areas including:

  • GDF15 and Related Biomarkers
  • Nutrition and Health in Aging
  • Mitochondrial Function and Pathology
  • Diet and metabolism studies
  • Genetics, Aging, and Longevity in Model Organisms
  • Muscle Physiology and Disorders
  • Fatty Acid Research and Health

Frequent co-authors who have collaborated extensively with Cohen include Kelvin Yen, Junxiang Wan, Hiroshi Kumagai, Hemal H. Mehta, and Brendan Miller.

Their publications appear regularly in venues such as Aging, Cancer Research, Scientific Reports, Molecular Psychiatry, and the Journal of Clinical Oncology, highlighting an active engagement with diverse biomedical research outlets.

Recent notable papers authored or co-authored by Pinchas Cohen include:

  • "Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway," 2020, Molecular Therapy - Nucleic Acids
  • "The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan," 2020, Aging
  • "Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples," 2021, Scientific Reports
  • "Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications," 2020, Experimental Cell Research
  • "Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models," 2022, Cell Reports

The body of work evident from these publications illustrates a blend of molecular biology, mitochondrial research, aging mechanisms, and metabolic studies, frequently intersecting with clinical and translational outcomes.

Best Publications

  • Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: Summary statement of the GH research society

    Kenneth M. Attie;Bengt Ake Bengtsson;Sandra L. Blethen;Werner Blum

  • Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

    Morgan E. Levine;Jorge A. Suarez;Sebastian Brandhorst;Priya Balasubramanian

  • A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

    Sebastian Brandhorst;In Young Choi;Min Wei;Chia Wei Cheng

  • Functionally significant insulin-like growth factor I receptor mutations in centenarians

    Yousin Suh;Gil Atzmon;Mi Ook Cho;David Hwang

  • Insulin-like Growth Factor (IGF)-binding Protein-3 Induces Apoptosis and Mediates the Effects of Transforming Growth Factor-β1 on Programmed Cell Death through a p53- and IGF-independent Mechanism

    Roopmathy Rajah;Barbara Valentinis;Pinchas Cohen

  • Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.

    Jaime Guevara-Aguirre;Priya Balasubramanian;Marco Guevara-Aguirre;Min Wei

  • Role of insulin‐like growth factors and their binding proteins in growth control and carcinogenesis

    Adda Grimberg;Pinchas Cohen

  • Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults

    Julio Licinio;Sinan Caglayan;Metin Ozata;Bulent O. Yildiz

  • Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.

    Pinchas Cohen;Howard C.B. Graves;Donna M. Peehl;Mehdi Kamarei

  • The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

    Changhan Lee;Jennifer Zeng;Brian G. Drew;Tamer Sallam

  • Consensus Statement on the Diagnosis and Treatment of Children with Idiopathic Short Stature: A Summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop

    P. Cohen;A. D. Rogol;C. L. Deal;P. Saenger

  • Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.

    Min Wei;Sebastian Brandhorst;Mahshid Shelehchi;Hamed Mirzaei

  • EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3

    Alexandre Prieur;Franck Tirode;Pinchas Cohen;Olivier Delattre

  • Fasting and cancer treatment in humans: A case series report

    Fernando M. Safdie;Tanya Dorff;David Quinn;Luigi Fontana

  • Surgical removal of visceral fat reverses hepatic insulin resistance.

    Nir Barzilai;Li She;Bing Qian Liu;Patricia Vuguin

  • Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells.

    Pinchas Cohen;Donna M. Peehl;George Lamson;Ron G. Rosenfeld

  • Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

    Sarah J. Mitchell;Julio Madrigal-Matute;Morten Scheibye-Knudsen;Morten Scheibye-Knudsen;Evandro Fang

  • The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene.

    Barbara Valentinis;Ajay Bhala;Tiziana DeAngelis;Renato Baserga

  • Direct Functional Interactions between Insulin-like Growth Factor-binding Protein-3 and Retinoid X Receptor-α Regulate Transcriptional Signaling and Apoptosis

    Bingrong Liu;Ho Young Lee;Stuart A. Weinzimer;David R. Powell

  • Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.

    Maaria Ikonen;Bingrong Liu;Yuichi Hashimoto;Liqun Ma

Frequent Co-Authors

Ron G. Rosenfeld
Ron G. Rosenfeld Oregon Health & Science University
William J. Aronson
William J. Aronson University of California, Los Angeles
Valter D. Longo
Valter D. Longo University of Southern California
Nir Barzilai
Nir Barzilai Albert Einstein College of Medicine
Jonathan W. Said
Jonathan W. Said University of California, Los Angeles
David Elashoff
David Elashoff University of California, Los Angeles
Stephen J. Freedland
Stephen J. Freedland Cedars-Sinai Medical Center
Amir Lerman
Amir Lerman Mayo Clinic
Donna M. Peehl
Donna M. Peehl University of California, San Francisco
Susanne M. Henning
Susanne M. Henning University of California, Los Angeles

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