Dirk W. Heinz

Overview

Best Publications

• Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect.

  A. E. Eriksson;W. A. Baase;X. J. Zhang;D. W. Heinz

  1219
  Citations

• Structure and function of enzymes in heme biosynthesis.

  Gunhild Layer;Joachim Reichelt;Dieter Jahn;Dirk W. Heinz

  419
  Citations

• Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin

  Wolf Dieter Schubert;Claus Urbanke;Thilo Ziehm;Viola Beier

  366
  Citations

• Targeting DnaN for tuberculosis therapy using novel griselimycins

  Angela Kling;Peer Lukat;Deepak V. Almeida;Armin Bauer

  331
  Citations

• Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes

  Gunhild Layer;Jürgen Moser;Dirk W. Heinz;Dieter Jahn

  330
  Citations

• Extending the Host Range of Listeria monocytogenes by Rational Protein Design

  Thomas Wollert;Bastian Pasche;Maike Rochon;Stefanie Deppenmeier

  265
  Citations

• Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.

  Isabel Astner;Jörg O Schulze;Joop van den Heuvel;Dieter Jahn

  264
  Citations

• Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol.

  D W Heinz;M Ryan;T L Bullock;O H Griffith

  219
  Citations

• Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb

  Hartmut H. Niemann;Volker Jäger;P. Jonathan G. Butler;Joop van den Heuvel

  186
  Citations

• Plasmin(Ogen)-Binding Alpha-Enolase from Streptococcus Pneumoniae: Crystal Structure and Evaluation of Plasmin(Ogen)-Binding Sites

  Stefanie Ehinger;Wolf-Dieter Schubert;Simone Bergmann;Sven Hammerschmidt

  185
  Citations

• Adhesins and invasins of pathogenic bacteria: a structural view

  Hartmut H Niemann;Wolf Dieter Schubert;Dirk W Heinz

  173
  Citations

• Structural and Mechanistic Comparison of Prokaryotic and Eukaryotic Phosphoinositide-specific Phospholipases C

  Dirk W. Heinz;Lars-Oliver Essen;Roger L. Williams

  157
  Citations

• V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis.

  Jürgen Moser;Jürgen Moser;Wolf-Dieter Schubert;Viola Beier;Ingo Bringemeier

  149
  Citations

• Structure and function of radical SAM enzymes

  Gunhild Layer;Dirk W Heinz;Dieter Jahn;Wolf-Dieter Schubert

  142
  Citations

• Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain.

  Wolf-Dieter Schubert;Gero Göbel;Meikel Diepholz;Ayub Darji

  138
  Citations

• The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases

  Gregor Hagelueken;Thorsten M. Adams;Thorsten M. Adams;Lutz Wiehlmann;Ute Widow

  136
  Citations

• The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.

  Susanne Frese;Wolf-Dieter Schubert;Antje C. Findeis;Tobias Marquardt

  133
  Citations

• In situ structural analysis of the Yersinia enterocolitica injectisome

  Mikhail Kudryashev;Marco Stenta;Stefan Schmelz;Marlise Amstutz

  130
  Citations

• High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.

  Nicole Frankenberg;Peter T. Erskine;Jon B. Cooper;Peter M. Shoolingin-Jordan

  117
  Citations

• The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA‐binding affinity by stabilizing the HTH motif

  Marina Eiting;Gregor Hagelüken;Wolf-Dieter Schubert;Dirk W. Heinz

  112
  Citations