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Marcella Mottolese

Marcella Mottolese

D-Index & Metrics

Molecular Biology

D-Index
62
Citations
11155
World Ranking
1866
National Ranking
37

Overview

Marcella Mottolese is affiliated with the IRCCS Regina Elena Institute in Italy. Their research predominantly spans the field of Medicine, with a specific focus on Oncology. The scientist's work includes contributions in subfields such as Oncology, Physiology, Pathology and Forensic Medicine, Neurology, and Cancer Research.

Their research topics include:

  • Cancer-related Molecular Pathways
  • Colorectal Cancer Surgical Treatments
  • Telomeres, Telomerase, and Senescence
  • Genetic factors in colorectal cancer
  • Neuroblastoma Research and Treatments
  • Cytokine Signaling Pathways and Interactions
  • Breast Cancer Treatment Studies

Marcella Mottolese has published papers in several journals, including:

  • Journal of Experimental & Clinical Cancer Research
  • Oncology Reports
  • Clinical Breast Cancer

Notable recent publications include:

  • TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients, 2020, Journal of Experimental & Clinical Cancer Research
  • HIPK2 is a potential predictive marker of a favorable response for adjuvant chemotherapy in stage II colorectal cancer, 2020, Oncology Reports
  • p53 and BLC2 Immunohistochemical Expression Across Molecular Subtypes in 1099 Early Breast Cancer Patients With Long-Term Follow-up: An Observational Study, 2020, Clinical Breast Cancer

The scientist has collaborated frequently with several co-authors, including:

  • Simonetta Buglioni
  • Carla Azzurra Amoreo
  • Isabella Sperduti
  • Giuliana Di Rocco
  • Alessandra Verdina

Best Publications

  • Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

    Silvia Di Agostino;Sabrina Strano;Velia Emiliozzi;Valentina Zerbini

  • The α3β1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (mmp‐9) activity

    Monica Morini;Marcella Mottolese;Nicoletta Ferrari;Federica Ghiorzo

  • TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells.

    M Bartucci;R Dattilo;C Moriconi;A Pagliuca

  • The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

    Enzo Medico;Mariangela Russo;Gabriele Picco;Carlotta Cancelliere

  • Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

    Erica Salvati;Carlo Leonetti;Angela Rizzo;Marco Scarsella

  • The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis

    Giulia Fontemaggi;Stefania Dell'Orso;Daniela Trisciuoglio;Tal Shay

  • miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer

    A Sacconi;F Biagioni;V Canu;F Mori

  • KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.

    Emanuele Valtorta;Sandra Misale;Andrea Sartore-Bianchi;Iris D. Nagtegaal

  • Immunohistochemical expression of p16 INK4a is predictive of HR-HPV infection in cervical low-grade lesions

    Maria Benevolo;Marcella Mottolese;Ferdinando Marandino;Giuseppe Vocaturo

  • Breast cancer is associated with loss of the c-kit oncogene product.

    P. G. Natali;M. R. Nicotra;I. Sures;M. Mottolese

  • Clinical outcome of patients with brain metastases from HER2-positive breast cancer treated with lapatinib and capecitabine

    G. Metro;J. Foglietta;M. Russillo;L. Stocchi

  • c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings.

    Annamaria Biroccio;Barbara Benassi;Igea D’Agnano;Carmen D’Angelo

  • Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line

    Annamaria Biroccio;Antonio Candiloro;Marcella Mottolese;Orazio Sapora

  • A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

    Abeer M. Shaaban;Graham R. Ball;Rebecca A. Brannan;Rebecca A. Brannan;Gabor Cserni

  • Diagnostic and prognostic value of peritoneal immunocytology in gastric cancer.

    Maria Benevolo;Marcella Mottolese;Maurizio Cosimelli;Manfredo Tedesco

  • Increase of cisplatin sensitivity by c-myc antisense oligodeoxynucleotides in a human metastatic melanoma inherently resistant to cisplatin.

    Carlo Leonetti;Annamaria Biroccio;Antonio Candiloro;Gennaro Citro

  • Triple positive breast cancer: a distinct subtype?

    Patrizia Vici;Laura Pizzuti;Clara Natoli;Teresa Gamucci

  • Endothelial NOS, estrogen receptor β, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer

    Simona Nanni;Valentina Benvenuti;Annalisa Grasselli;Carmen Priolo

  • Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: Independent prognostic role of p53 and bcl-2

    Simonetta Buglioni;Igea D'Agnano;Maurizio Cosimelli;Stefania Vasselli

  • Cyclooxygenase-2 (COX-2), epidermal growth factor receptor (EGFR), and Her-2/neu expression in ovarian cancer.

    G. Ferrandina;F.O. Ranelletti;L. Lauriola;F. Fanfani

Frequent Co-Authors

Pier Giorgio Natali
Pier Giorgio Natali PharmaMab S.r.l.
Diana Giannarelli
Diana Giannarelli Sapienza University of Rome
Francesco Cognetti
Francesco Cognetti Sapienza University of Rome
Ruggero De Maria
Ruggero De Maria Catholic University of the Sacred Heart
Gabriella Zupi
Gabriella Zupi École Normale Supérieure de Lyon
Michele Milella
Michele Milella University of Verona
Giovanni Blandino
Giovanni Blandino McMaster University
Paolo Visca
Paolo Visca Roma Tre University
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
Patrizio Giacomini
Patrizio Giacomini Sapienza University of Rome

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